Matrin 3 Antibody

Matrin 3 is a nuclear matrix protein that has been observed to mediate multiple cellular processes. Matrin 3 can function to withhold defective RNAs within the nucleus by anchoring them to the nuclear matrix and modulate the promoter activity of genes proximal to matrix/scaffold attachment region (MAR/SAR). Matrin 3 has also been demonstrated to be the main PKA substrate following NMDA receptor activation in NMDA-induced neuronal cell death. Alternate names for Matrin 3 include MATR3, MGC9105, KIAA0723, DKFZp686K0542, and DKFZp686K23100.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 4 applications: ICC/IF, IP, KD, WB.

Showing Publications 1 - 10 of 13. Show All 13 Publications. Collapse Publications.

Publications using NB100-1761	Applications	Species
Guo Q, Han S The effect on m6A methylation writer complex by the reduced MATR3 in pterygium Acta histochemica 2023-10-30 [PMID: 37913560]
Haikerwal A, Barrera MD, Bhalla N et al. Inhibition of Venezuelan Equine Encephalitis Virus Using Small Interfering RNAs Viruses 2022-07-26 [PMID: 35893693] (IP, KD, WB, Human) Details: See Supplementary figure for KD	IP, KD, WB	Human
Moloney C, Rayaprolu S, Howard J et al. Analysis of spinal and muscle pathology in transgenic mice overexpressing wild-type and ALS-linked mutant MATR3 Acta Neuropathol Commun 2018-12-19 [PMID: 30563574] (WB, Mouse)	WB	Mouse
Marangi G, Lattante S, Doronzio PN et al. Matrin 3 variants are frequent in Italian ALS patients. Neurobiol Aging 2017-01-01 [PMID: 28029397]
Moloney C, Rayaprolu S, Howard J et al. Transgenic mice overexpressing the ALS-linked protein Matrin 3 develop a profound muscle phenotype. Acta Neuropathol Commun. 2016-11-18 [PMID: 27863507] (WB, Mouse)	WB	Mouse
Rayaprolu S, D'Alton S, Crosby K et al. Heterogeneity of Matrin 3 in the developing and aging murine central nervous system. J Comp Neurol 2016-10-01 [PMID: 26878116] (Mouse)		Mouse
Christopher A. Yarosh, Iulia Tapescu, Matthew G. Thompson et al. TRAP150 interacts with the RNA-binding domain of PSF and antagonizes splicing of numerous PSF-target genes in T cells. Nucleic Acid Research 2015-08-10 [PMID: 26261210] (WB, Human)	WB	Human
Moldovan JB, Moran JV. The Zinc-Finger Antiviral Protein ZAP Inhibits LINE and Alu Retrotransposition. PLoS Genet 2015-05-01 [PMID: 25951186] (ICC/IF, WB, Human)	ICC/IF, WB	Human
Depreux FF, Puckelwartz MJ, Augustynowicz A et al. Disruption of the lamin A and matrin-3 interaction by myopathic LMNA mutations. Hum. Mol. Genet. 2015-05-06 [PMID: 25948554] (IP, WB, Mouse)	IP, WB	Mouse
Lee YW, Terranova C, Birkaya B et al. A novel nuclear FGF Receptor-1 partnership with retinoid and Nur receptors during developmental gene programming of embryonic stem cells. J Cell Biochem 2012-09-01 [PMID: 22539306]
Salton M, Elkon R, Borodina T et al. Matrin 3 binds and stabilizes mRNA. PLoS One 2011-01-01 [PMID: 21858232]
Erazo A, Yee MB, Banfield BW et al. The alphaherpesvirus US3/ORF66 protein kinases direct phosphorylation of the nuclear matrix protein matrin 3. J Virol 2011-01-01 [PMID: 20962082]
Schessl J, Zou Y, McGrath MJ et al. Proteomic identification of FHL1 as the protein mutated in human reducing body myopathy. J Clin Invest 2008-03-01 [PMID: 18274675]
Show All 13 Publications. Collapse Publications.

Images	Ratings	Applications	Species	Date	Details
Enlarge	5 reviewed by: Jennifer Fox	IP	Human	09/12/2014	View Summary Application Immunoprecipitation Sample Tested Human fibroblasts Species Human Lot A1

Array NB100-1761

• Matrin 3 Antibodies
• Matrin 3 ELISA Kits
• Matrin 3 Lysates
• Matrin 3 Proteins