LIM Kinase 1/2 [p Thr508] Antibody - BSA Free Summary
Immunogen |
A peptide sequence around phosphorylation site of threonine 508 (R-Y-T (p) -V-V) derived from Human LIMK1 |
Modification |
p Thr508 |
Specificity |
This antibody detects endogenous level of LIM Kinase 1/2 only when phosphorylated at threonine 508. |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
LIMK1 |
Purity |
Epitope affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunocytochemistry/ Immunofluorescence 1:100-1:200
- Immunohistochemistry 1:50-1:100
- Immunohistochemistry-Paraffin 1:10-1:500
- Western Blot 1:500-1:1000
|
Theoretical MW |
72 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
Storage |
Store at -20 degrees C. Avoid freeze/thaw cycles. |
Buffer |
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, and 50% glycerol. |
Preservative |
0.02% Sodium Azide |
Concentration |
1 mg/ml |
Purity |
Epitope affinity purified |
Alternate Names for LIM Kinase 1/2 [p Thr508] Antibody - BSA Free
Background
Protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. Isoform 3 has a dominant negative effect on actin cytoskeletal changes. May be involved in brain development.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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