Human Total PDGF R alpha DuoSet IC ELISA, 2 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

PDGF R alpha (Platelet-Derived Growth Factor Receptor alpha) is a transmembrane receptor tyrosine kinase that can form homodimers or heterodimers with PDGF R beta when engaged by dimers of the PDGF ligands. PDGF R alpha binds to PDGF-AA, PDGF-AB, and PDGF-CC. It is strongly expressed in oligodendrocyte, lung, skin, and intestinal progenitor cells, at low levels in most mesenchymal cells, and can be induced by inflammation. PDGF R alpha function is important during formation of the cranial and cardiac neural crest, retina, gonads, lung alveoli, intestinal villi, skin, hair follicles, skeleton, teeth, palate, and interstitial kidney mesenchyme. Dysregulated PDGF R alpha signaling can result in spina bifida or cleft palate-type malformations. Postnatally, PDGF R alpha is implicated in gliomas and fibrotic disorders of lung, heart, and skin (scleroderma).

We have publications tested in 1 confirmed species: Human.

Showing Publication 1 - 1 of 1.

Publication using DYC322-2	Applications	Species
Aderhold C, Faber A, Grobschmidt G, Chakraborty A, Bockmayer A, Umbreit C, Birk R, Stern-Straeter J, Hormann K, Schultz J Small molecule-based chemotherapeutic approach in p16-positive and -negative HNSCC in vitro. Anticancer Res, 2013-12-01;33(12):5385-93. 2013-12-01 [PMID: 24324073] (Human)		Human

Array DYC322-2

• PDGFR alpha Antibodies
• PDGFR alpha Antibody Pair
• PDGFR alpha Lysate
• PDGFR alpha Protein
• PDGFR alpha ELISAs
• PDGFR alpha Proteins and Enzymes