Human CXCL12/SDF-1 DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

CXCL12/Stromal Cell-derived Factor 1 (SDF-1) is a member of the CXC chemokine ligand superfamily. Six alternatively spliced CXCL12/SDF-1 isoforms have been identified including, CXCL12/SDF-1 alpha, CXCL12/SDF-1 beta, and CXCL12/SDF-1 gamma. CXCL12/SDF-1 alpha is 89 amino acids (aa) in length with a predicted molecular weight of 10 kDa, CXCL12/SDF-1 beta is 93 aa in length with a predicted molecular weight of 10.6 kDa, and CXCL12/SDF-1 gamma is 119 aa in length with a predicted molecular weight of 13.7 kDa. The mouse CXCL12/SDF-1 orthologs share 99% aa sequence identity with the human protein. The alpha and beta isoforms are ubiquitously expressed while the gamma isoform is primarily expressed in the heart. CXCL12/SDF-1 isoforms are chemotactic for T lymphocytes and monocytes. It is cardio protective and has also been shown to hinder CXCR4-mediated HIV infection of T cells.

We have publications tested in 3 confirmed species: Human, Rat, Feline.

Showing Publications 1 - 10 of 33. Show All 33 Publications. Collapse Publications.

Publications using DY350	Applications	Species
Lai, TY;Chiang, TC;Lee, CY;Kuo, TC;Wu, CH;Chen, YI;Hu, CM;Maskey, M;Tang, SC;Jeng, YM;Tien, YW;Lee, EYP;Lee, WH; Unraveling the impact of cancer-associated fibroblasts on hypovascular pancreatic neuroendocrine tumors British journal of cancer 2024-02-10 [PMID: 38341509] (Human)		Human
Juhász, L;L?rincz, H;Szentpéteri, A;Tóth, N;Varga, É;Paragh, G;Harangi, M; Decreased Serum Stromal Cell-Derived Factor-1 in Patients with Familial Hypercholesterolemia and Its Strong Correlation with Lipoprotein Subfractions International journal of molecular sciences 2023-10-18 [PMID: 37894988] (Human)		Human
You, S;Chen, H;Miao, M;Du, J;Che, B;Xu, T;Liu, CF;Zhang, Y;He, J;Zhong, X;Cao, Y;Zhong, C; Prognostic significance of plasma SDF-1 in acute ischemic stroke patients with diabetes mellitus: the CATIS trial Cardiovascular diabetology 2023-10-10 [PMID: 37817149] (Human)		Human
SK Kim, JY Choe, KY Park CXCL12 and CXCR4 as Novel Biomarkers in Uric Acid-Induced Inflammation and Patients with Gouty Arthritis Biomedicines, 2023-02-21;11(3):. 2023-02-21 [PMID: 36979628] (Human)		Human
W Alturaiki, H Alkadi, S Alamri, ME Awadalla, A Alfaez, A Mubarak, MA Alanazi, FQ Alenzi, BF Flanagan, B Alosaimi Association between the expression of Toll-like receptors, cytokines, and homeostatic chemokines in SARS-CoV-2 infection and COVID-19 severity Heliyon, 2022-12-24;0(0):e12653. 2022-12-24 [PMID: 36589720] (Human)		Human
M Ackermann, JC Kamp, C Werlein, CL Walsh, H Stark, V Prade, R Surabattul, WL Wagner, C Disney, AJ Bodey, T Illig, DJ Leeming, MA Karsdal, A Tzankov, P Boor, MP Kühnel, FP Länger, SE Verleden, HM Kvasnicka, HH Kreipe, A Haverich, SM Black, A Walch, P Tafforeau, PD Lee, MM Hoeper, T Welte, B Seeliger, S David, D Schuppan, SJ Mentzer, DD Jonigk The fatal trajectory of pulmonary COVID-19 is driven by lobular ischemia and fibrotic remodelling EBioMedicine, 2022-10-04;85(0):104296. 2022-10-04 [PMID: 36206625] (Human)		Human
S Rutecki, P Szulc, M Paku?a, P Uruski, A Radziemski, E Naumowicz, R Moszy?ski, A Tykarski, J Miku?a-Pie, K Ksi??ek Pro-cancerogenic effects of spontaneous and drug-induced senescence of ovarian cancer cells in vitro and in vivo: a comparative analysis Journal of ovarian research, 2022-07-26;15(1):87. 2022-07-26 [PMID: 35883110] (Human)		Human
K D?bkowski, A ?ab?d?-Mas, B Do??gowska, K Safranow, M Budkowska, E Zuba-Surma, T Starzy?ska Evidence of Stem Cells Mobilization in the Blood of Patients with Pancreatitis: A Potential Link with Disease Severity Stem Cells International, 2022-07-08;2022(0):5395248. 2022-07-08 [PMID: 35846982] (Human)		Human
L Garcia-Ger, M García, A Garrido-Ga, S Gómez-Gonz, M Torrebadel, E Prada, G Pascual-Pa, O Muñoz, S Perez-Jaum, I Lemos, N Salvador, M Vila-Ubach, A Doncel-Req, M Suñol, AM Carcaboso, J Mora, C Lavarino MIF/CXCR4 signaling axis contributes to survival, invasion, and drug resistance of metastatic neuroblastoma cells in the bone marrow microenvironment BMC Cancer, 2022-06-17;22(1):669. 2022-06-17 [PMID: 35715791] (Human)		Human
D Bernareggi, Q Xie, BC Prager, J Yun, LS Cruz, TV Pham, W Kim, X Lee, M Coffey, C Zalfa, P Azmoon, H Zhu, P Tamayo, JN Rich, DS Kaufman CHMP2A regulates tumor sensitivity to natural killer cell-mediated cytotoxicity Nature Communications, 2022-04-07;13(1):1899. 2022-04-07 [PMID: 35393416] (Human)		Human
SF Mause, E Ritzel, A Deck, F Vogt, EA Liehn Engagement of the CXCL12-CXCR4 Axis in the Interaction of Endothelial Progenitor Cell and Smooth Muscle Cell to Promote Phenotype Control and Guard Vascular Homeostasis International Journal of Molecular Sciences, 2022-01-14;23(2):. 2022-01-14 [PMID: 35055054] (Human)		Human
VA Guarino, A Blau, J Alvarenga, J Loscalzo, YY Zhang A Crosslinked Dextran Sulfate-Chitosan Nanoparticle for Delivery of Therapeutic Heparin-binding Proteins International journal of pharmaceutics, 2021-11-11;0(0):121287. 2021-11-11 [PMID: 34775044] (Rat)		Rat
E Yeregui, C Viladés, P Domingo, A Ceausu, YM Pacheco, S Veloso, A Inciarte, J Vidal-Gonz, M Peraire, C Perpiñán, V Falcó, J Masip, V Alba, M Vargas, A Martí, L Reverté, J Mallolas, F Vidal, J Peraire, A Rull High circulating SDF-1and MCP-1 levels and genetic variations in CXCL12, CCL2 and CCR5: Prognostic signature of immune recovery status in treated HIV-positive patients EBioMedicine, 2020-11-06;62(0):103077. 2020-11-06 [PMID: 33166788] (Human)		Human
S Hässler, D Bachelet, J Duhaze, N Szely, A Gleizes, S Hacein-Bey, O Aktas, M Auer, J Avouac, M Birchler, Y Bouhnik, O Brocq, D Buck-Marti, G Cadiot, F Carbonnel, Y Chowers, M Comabella, T Derfuss, N De Vries, N Donnellan, A Doukani, M Guger, HP Hartung, E Kubala Hav, B Hemmer, T Huizinga, K Ingenhoven, PE Hyldgaard-, EC Jury, M Khalil, B Kieseier, A Laurén, R Lindberg, A Loercher, E Maggi, J Manson, C Mauri, B Mohand Oum, X Montalban, M Nachury, P Nytrova, C Richez, M Ryner, F Sellebjerg, C Sievers, D Sikkema, M Soubrier, S Tourdot, C Trang, A Vultaggio, C Warnke, S Spindeldre, P Dönnes, TP Hickling, A Hincelin M, M Allez, F Deisenhamm, A Fogdell-Ha, X Mariette, M Pallardy, P Broët, ABIRISK co Clinicogenomic factors of biotherapy immunogenicity in autoimmune disease: A prospective multicohort study of the ABIRISK consortium PLoS Med, 2020-10-30;17(10):e1003348. 2020-10-30 [PMID: 33125391] (Human)		Human
M Tutter, C Schug, KA Schmohl, S Urnauer, C Kitzberger, N Schwenk, M Petrini, C Zach, S Ziegler, P Bartenstei, WA Weber, G Multhoff, E Wagner, LH Lindner, PJ Nelson, C Spitzweg Regional hyperthermia enhances mesenchymal stem cell recruitment to tumor stroma: Implications for mesenchymal stem cell-based tumor therapy Mol Ther, 2020-10-15;0(0):. 2020-10-15 [PMID: 33068779] (Human)		Human
J Ohmes, Y Xiao, F Wang, MD Mikkelsen, TT Nguyen, H Schmidt, A Seekamp, AS Meyer, S Fuchs Effect of Enzymatically Extracted Fucoidans on Angiogenesis and Osteogenesis in Primary Cell Culture Systems Mimicking Bone Tissue Environment Mar Drugs, 2020-09-21;18(9):. 2020-09-21 [PMID: 32967359] (Human)		Human
J O'Dwyer, M Cullen, S Fattah, R Murphy, S Stefanovic, L Kovarova, M Pravda, V Velebny, A Heise, GP Duffy, SA Cryan Development of a Sustained Release Nano-In-Gel Delivery System for the Chemotactic and Angiogenic Growth Factor Stromal-Derived Factor 1alpha Pharmaceutics, 2020-06-04;12(6):. 2020-06-04 [PMID: 32512712] (Human)		Human
M Colombo, S Garavelli, M Mazzola, N Platonova, D Giannandre, R Colella, L Apicella, M Lancellott, E Lesma, S Ancona, MT Palano, M Barbieri, E Taiana, E Lazzari, A Basile, M Turrini, A Pistocchi, A Neri, R Chiaramont Multiple myeloma exploits Jagged1 and Jagged2 to promote intrinsic and bone marrow-dependent drug resistance Haematologica, 2019-10-03;0(0):. 2019-10-03 [PMID: 31582544] (Human)		Human
M Paku?a, P Uruski, A Niklas, A Wo?niak, D Szpurek, A Tykarski, J Miku?a-Pie, K Ksi??ek A Unique Pattern of Mesothelial-Mesenchymal Transition Induced in the Normal Peritoneal Mesothelium by High-Grade Serous Ovarian Cancer Cancers (Basel), 2019-05-13;11(5):. 2019-05-13 [PMID: 31086083] (Human)		Human
U Hopfner, MM Aitzetmuel, P Ne beta bach, MS Hu, HG Machens, ZN Maan, D Duscher Fibrin Glue Enhances Adipose-Derived Stromal Cell Cytokine Secretion and Survival Conferring Accelerated Diabetic Wound Healing Stem Cells Int, 2018-12-19;2018(0):1353085. 2018-12-19 [PMID: 30662467] (Human)		Human
F Mizoguchi, K Slowikowsk, K Wei, JL Marshall, DA Rao, SK Chang, HN Nguyen, EH Noss, JD Turner, BE Earp, PE Blazar, J Wright, BP Simmons, LT Donlin, GD Kalliolias, SM Goodman, VP Bykerk, LB Ivashkiv, JA Lederer, N Hacohen, PA Nigrovic, A Filer, CD Buckley, S Raychaudhu, MB Brenner Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis Nat Commun, 2018-02-23;9(1):789. 2018-02-23 [PMID: 29476097] (Human)		Human
CS Marques, M Soares, A Santos, J Correia, F Ferreira Serum SDF-1 levels are a reliable diagnostic marker of feline mammary carcinoma, discriminating HER2-overexpressing tumors from other subtypes Oncotarget, 2017-11-11;8(62):105775-105789. 2017-11-11 [PMID: 29285291] (Feline)		Feline
BW Megra, EA Eugenin, JW Berman The Role of Shed PrP(c) in the Neuropathogenesis of HIV Infection J. Immunol., 2017-05-22;0(0):. 2017-05-22 [PMID: 28533442] (Human)		Human
Gabriela Odent Grig Synergic effects of VEGF-A and SDF-1 on the angiogenic properties of endothelial progenitor cells J Tissue Eng Regen Med, 2016-12-12;0(0):. 2016-12-12 [PMID: 27943613] (Human)		Human
Marco Santoro MODELING STROMA-INDUCED DRUG RESISTANCE IN A TISSUE-ENGINEERED TUMOR MODEL OF EWING SARCOMA Tissue Eng Part A, 2017-01-01;0(0):. 2017-01-01 [PMID: 27923328] (Human)		Human
Incorporation of heparin-binding proteins into preformed dextran sulfate-chitosan nanoparticles Int J Nanomedicine, 2016-11-18;11(0):6149-6159. 2016-11-18 [PMID: 27920522] (Rat)		Rat
Calcaterra F, Taddeo A, Colombo E, Cappelletti M, Martinelli A, Calabrese S, Mavilio D, Cetin I, Della Bella S Reduction of maternal circulating endothelial progenitor cells in human pregnancies with intrauterine growth restriction. Placenta, 2014-04-26;35(7):431-6. 2014-04-26 [PMID: 24819155] (Human)		Human
CXCR4 positive and angiogenic monocytes in myocardial infarction. Thromb Haemost, 2012-12-06;109(2):255-62. 2012-12-06 [PMID: 23223950] (Human)		Human
Yasumoto K, Yamada T, Kawashima A, Wang W, Li Q, Donev IS, Tacheuchi S, Mouri H, Yamashita K, Ohtsubo K, Yano S The EGFR ligands amphiregulin and heparin-binding egf-like growth factor promote peritoneal carcinomatosis in CXCR4-expressing gastric cancer. Clin. Cancer Res., 2011-04-11;17(11):3619-30. 2011-04-11 [PMID: 21482691] (Human)		Human
Zimmer A, Luce S, Gaignier F, Nony E, Naveau M, Biola-Vidamment A, Pallardy M, Van Overtvelt L, Mascarell L, Moingeon P Identification of a New Phenotype of Tolerogenic Human Dendritic Cells Induced by Fungal Proteases from Aspergillus oryzae. J. Immunol., 2011-03-02;186(7):3966-76. 2011-03-02 [PMID: 21368225] (Human)		Human
Chatterjee M, Huang Z, Zhang W, Jiang L, Hultenby K, Zhu L, Hu H, Nilsson GP, Li N Distinct platelet packaging, release, and surface expression of proangiogenic and antiangiogenic factors on different platelet stimuli. Blood, 2011-02-17;117(14):3907-11. 2011-02-17 [PMID: 21330475] (Human)		Human
Ouwehand K, Santegoets SJ, Bruynzeel DP, Scheper RJ, de Gruijl TD, Gibbs S CXCL12 is essential for migration of activated Langerhans cells from epidermis to dermis. Eur. J. Immunol., 2008-11-01;38(11):3050-9. 2008-11-01 [PMID: 18924211] (Human)		Human
Jung Y, Wang J, Schneider A, Sun YX, Koh-Paige AJ, Osman NI, McCauley LK, Taichman RS Regulation of SDF-1 (CXCL12) production by osteoblasts; a possible mechanism for stem cell homing. Bone, 2005-12-05;38(4):497-508. 2005-12-05 [PMID: 16337237] (Human)		Human
Show All 33 Publications. Collapse Publications.

Array DY350

• CXCL12/SDF-1 Antibodies
• CXCL12/SDF-1 ELISA Kits
• CXCL12/SDF-1 Lysate
• CXCL12/SDF-1 Proteins
• CXCL12/SDF-1 ELISAs