CXCL8/IL-8 Antibody (6217) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 9 confirmed species: Human, Mouse, Rat, Bacteria - E. Coli, Bacteria - Porphyromonas gingivalis, Bovine, Complex Species Category, Guinea Pig, Rabbit.

We have publications tested in 24 applications: Affinity Chromatography, Antibody Array Development, Array Development, Binding Assay, Bioassay, Blocking, Co-Immunoprecipitation, ELISA Capture, ELISA Development, ELISA Development (Capture), ELISA Development (Detection), Electrochemiluminescent Assay, Flow Cytometry, Functional Assay, ICC, IHC, IHC-Fr, IHC-P, Immunohistochemistry, Immunoprecipitation, Inhibition, Luminex Development, Neutralization, Western Blot.

Showing Publications 1 - 10 of 183. Show All 183 Publications. Collapse Publications.

Publications using MAB208	Applications	Species
Chan, ASL;Zhu, H;Narita, M;Cassidy, LD;Young, ARJ;Bermejo-Rodriguez, C;Janowska, AT;Chen, HC;Gough, S;Oshimori, N;Zender, L;Aitken, SJ;Hoare, M;Narita, M; Titration of RAS alters senescent state and influences tumour initiation Nature 2024-08-07 [PMID: 39112713] (Immunohistochemistry, Western Blot, Mouse)	Immunohistochemistry, Western Blot	Mouse
Chien, Y;Huang, XY;Yarmishyn, AA;Chien, CS;Liu, YH;Hsiao, YJ;Lin, YY;Lai, WY;Huang, SC;Lee, MS;Chiou, SH;Yang, YP;Chiou, GY; Paracrinal regulation of neutrophil functions by coronaviral infection in iPSC-derived alveolar type II epithelial cells Virus research 2024-07-01 [PMID: 38754785] (Neutralization, Human)	Neutralization	Human
Kim, HJ;Chang, HK;Lee, YM;Heo, K; Catecholamines Promote Ovarian Cancer Progression through Secretion of CXC-Chemokines International journal of molecular sciences 2023-09-14 [PMID: 37762405] (Neutralization, Human)	Neutralization	Human
Chen Z, Will R, Kim SN et al. Novel Function of Cancer Stem Cell Marker ALDH1A3 in Glioblastoma: Pro-Angiogenesis through Paracrine PAI-1 and IL-8 Cancers (Basel) 2023-09-04 [PMID: 37686698]
Chen Z, Will R, Kim SN et al. Novel Function of Cancer Stem Cell Marker ALDH1A3 in Glioblastoma: Pro-Angiogenesis through Paracrine PAI-1 and IL-8 Cancers (Basel) 9/4/2023 [PMID: 37686698]
Shen, CJ;Chan, RH;Lin, BW;Li, NC;Huang, YH;Chang, WC;Chen, BK; Oleic acid-induced metastasis of KRAS/p53-mutant colorectal cancer relies on concurrent KRAS activation and IL-8 expression bypassing EGFR activation Theranostics 2023-08-21 [PMID: 37649607] (Western Blot, Human)	Western Blot	Human
Yang, JL;Lin, WL;Tai, SB;Ciou, YS;Chung, CL;Chen, JJ;Liu, PF;Lin, MW;Chen, CL; Suppression of TGF beta -Induced Interleukin-6 Secretion by Sinulariolide from Soft Corals through Attenuation of the p38-NF-kB Pathway in Carcinoma Cells International journal of molecular sciences 2023-07-19 [PMID: 37511415] (Western Blot, Human)	Western Blot	Human
Edmée Eyraud, Elise Maurat, Jean-Marc Sac-Epée, Pauline Henrot, Maeva Zysman, Pauline Esteves et al. Short-range interactions between fibrocytes and CD8+ T cells in COPD bronchial inflammatory response eLife 7/26/2023 [PMID: 37494277]
Fu, X;Pereira, R;Liu, CC;De Angelis, C;Shea, MJ;Nanda, S;Qin, L;Mitchell, T;Cataldo, ML;Veeraraghavan, J;Sethunath, V;Giuliano, M;Gutierrez, C;Győrffy, B;Trivedi, MV;Cohen, O;Wagle, N;Nardone, A;Jeselsohn, R;Rimawi, MF;Osborne, CK;Schiff, R; High FOXA1 levels induce ER transcriptional reprogramming, a pro-metastatic secretome, and metastasis in endocrine-resistant breast cancer Cell reports 2023-07-18 [PMID: 37467106] (Neutralization, Human)	Neutralization	Human
Zhao, C;Wang, D;Li, Z;Zhang, Z;Xu, Y;Liu, J;Lei, Q;Han, D;Huo, Y;Liu, S;Li, L;Zhang, Y; IL8 derived from macrophages inhibits CD8+ T-cell function by downregulating TIM3 expression through IL8-CXCR2 axis in patients with advanced colorectal cancer International immunopharmacology 2023-06-16 [PMID: 37331296] (ICC, IHC, Neutralization, Human)	ICC, IHC, Neutralization	Human
Smer-Barreto, V;Quintanilla, A;Elliott, RJR;Dawson, JC;Sun, J;Campa, VM;Lorente-Macías, Á;Unciti-Broceta, A;Carragher, NO;Acosta, JC;Oyarzún, DA; Discovery of senolytics using machine learning Nature communications 2023-06-10 [PMID: 37301862] (ICC, Human)	ICC	Human
Huang, J;Wang, X;Wen, J;Zhao, X;Wu, C;Wang, L;Cao, X;Dong, H;Xu, X;Huang, F;Zhu, W;Wang, M; Gastric cancer cell-originated small extracellular vesicle induces metabolic reprogramming of BM-MSCs through ERK-PPAR?-CPT1A signaling to potentiate lymphatic metastasis Cancer cell international 2023-05-09 [PMID: 37158903] (Neutralization, Human)	Neutralization	Human
Ming-Na Zhao, Ling-Fei Zhang, Zhen Sun, Li-Hua Qiao, Tao Yang, Yi-Zhe Ren et al. A novel microRNA-182/Interleukin-8 regulatory axis controls osteolytic bone metastasis of lung cancer Cell Death & Disease 5/1/2023 [PMID: 37127752]
YJ Kahm, IG Kim, RK Kim RanBP1: A Potential Therapeutic Target for Cancer Stem Cells in Lung Cancer and Glioma International Journal of Molecular Sciences, 2023-04-06;24(7):. 2023-04-06 [PMID: 37047826] (Neutralization, Human)	Neutralization	Human
S Lee, YJ Seo, JY Choi, X Che, HJ Kim, SY Eum, MS Hong, SK Lee, DC Cho Effect of teriparatide on drug treatment of tuberculous spondylitis: an experimental study Scientific Reports, 2022-12-15;12(1):21667. 2022-12-15 [PMID: 36522387] (ELISA Capture, Human)	ELISA Capture	Human
Shuhai Chen, Mingyou Chen Schwann cells promote the migration and invasion of colorectal cancer cells via the activated NF-kappa B/IL-8 axis in the tumor microenvironment Frontiers in Oncology 11/17/2022 [PMID: 36465391]
W Zeng, L Xiong, W Wu, S Li, J Liu, L Yang, L Lao, P Huang, M Zhang, H Chen, N Miao, Z Lin, Z Liu, X Yang, J Wang, P Wang, E Song, Y Yao, Y Nie, J Chen, D Huang CCL18 signaling from tumor-associated macrophages activates fibroblasts to adopt a chemoresistance-inducing phenotype Oncogene, 2022-11-22;0(0):. 2022-11-22 [PMID: 36418470] (Flow Cytometry, Human)	Flow Cytometry	Human
S Sun, L Jin, Y Zheng, J Zhu Modeling human HSV infection via a vascularized immune-competent skin-on-chip platform Nature Communications, 2022-09-19;13(1):5481. 2022-09-19 [PMID: 36123328] (Neutralization, Human)	Neutralization	Human
Thiago Henrique Caldeira Oliveira, Vincent Vanheule, Sofie Vandendriessche, Fariba Poosti, Mauro Martins Teixeira, Paul Proost et al. The GAG-Binding Peptide MIG30 Protects against Liver Ischemia-Reperfusion in Mice International Journal of Molecular Sciences 8/26/2022 [PMID: 36077113]
MF Santolla, M Talia, F Cirillo, D Scordamagl, S De Rosis, A Spinelli, AM Miglietta, B Nardo, G Filippelli, EM De Frances, A Belfiore, R Lappano, M Maggiolini The AGEs/RAGE Transduction Signaling Prompts IL-8/CXCR1/2-Mediated Interaction between Cancer-Associated Fibroblasts (CAFs) and Breast Cancer Cells Cells, 2022-08-04;11(15):. 2022-08-04 [PMID: 35954247] (Bioassay, Human)	Bioassay	Human
R. C. Cornelison, J. X. Yuan, K. M. Tate, A. Petrosky, G. F. Beeghly, M. Bloomfield et al. A patient-designed tissue-engineered model of the infiltrative glioblastoma microenvironment npj Precision Oncology 7/29/2022 [PMID: 35906273]
R Islam, J Mishra, NS Polavaram, S Bhattachar, Z Hong, S Bodas, S Sharma, A Bouska, T Gilbreath, AM Said, LM Smith, BA Teply, MH Muders, SK Batra, K Datta, S Dutta Neuropilin-2 axis in regulating secretory phenotype of neuroendocrine-like prostate cancer cells and its implication in therapy resistance Oncogene, 2022-07-19;40(3):111097. 2022-07-19 [PMID: 35858551] (Western Blot, Human)	Western Blot	Human
Haoran Zhu, Keefe T Chan, Xinran Huang, Carmelo Cerra, Shaun Blake, Anna S Trigos et al. Cystathionine-beta -synthase is essential for AKT-induced senescence and suppresses the development of gastric cancers with PI3K/AKT activation eLife 6/27/2022 [PMID: 35758651]
Hoai-Nga Thi Nguyen, Marie Kawahara, Cat-Khanh Vuong, Mizuho Fukushige, Toshiharu Yamashita, Osamu Ohneda SARS-CoV-2 M Protein Facilitates Malignant Transformation of Breast Cancer Cells Frontiers in Oncology 6/7/2022 [PMID: 35747796]
Valerio Ciccone, Erika Terzuoli, Emma Ristori, Arianna Filippelli, Marina Ziche, Lucia Morbidelli et al. ALDH1A1 overexpression in melanoma cells promotes tumor angiogenesis by activating the IL‑8/Notch signaling cascade International Journal of Molecular Medicine 6/2/2022 [PMID: 35656893]
Kelvin Yin, Daniel Patten, Sarah Gough, Susana de Barros Gonçalves, Adelyne Chan, Ioana Olan et al. Senescence-induced endothelial phenotypes underpin immune-mediated senescence surveillance Genes & Development 5/1/2022 [PMID: 35618311]
T Walle, JA Kraske, B Liao, B Lenoir, C Timke, E von Bohlen, F Tran, P Griebel, D Albrecht, A Ahmed, M Suarez-Car, A Jiménez-Sá, T Beikert, A Tietz-Dahl, AN Menevse, G Schmidt, M Brom, JHW Pahl, W Antonopoul, M Miller, RL Perez, F Bestvater, NA Giese, P Beckhove, P Rosenstiel, D Jäger, O Strobel, D Pe'er, N Halama, J Debus, A Cerwenka, PE Huber Radiotherapy orchestrates natural killer cell dependent antitumor immune responses through CXCL8 Science Advances, 2022-03-23;8(12):eabh4050. 2022-03-23 [PMID: 35319989] (ICC, Human)	ICC	Human
Pamela J. Maxwell, Melanie McKechnie, Christopher W. Armstrong, Judith M. Manley, Chee Wee Ong, Jenny Worthington et al. Attenuating Adaptive VEGF-A and IL8 Signaling Restores Durable Tumor Control in AR Antagonist–Treated Prostate Cancers Molecular Cancer Research 6/3/2022 [PMID: 35302608]
E Lieschke, Z Wang, C Chang, CE Weeden, GL Kelly, A Strasser Flow cytometric single cell-based assay to simultaneously detect cell death, cell cycling, DNA content and cell senescence Cell Death and Differentiation, 2022-03-09;0(0):. 2022-03-09 [PMID: 35264779] (ICC, Human)	ICC	Human
F Yang, XQ Liu, JZ He, SP Xian, PF Yang, ZY Mai, M Li, Y Liu, XD Zhang Occludin facilitates tumour angiogenesis in bladder cancer by regulating IL8/STAT3 through STAT4 Journal of Cellular and Molecular Medicine, 2022-02-27;0(0):. 2022-02-27 [PMID: 35224833] (Bioassay, Human)	Bioassay	Human
Li Z, Fu WJ, Chen XQ et al. Autophagy-based unconventional secretion of HMGB1 in glioblastoma promotes chemosensitivity to temozolomide through macrophage M1-like polarization Journal of experimental & clinical cancer research : CR 2/22/2022 [PMID: 35193644]
RM Urbantat, C Jelgersma, S Brandenbur, M Nieminen-K, I Kremenetsk, J Zollfrank, S Mueller, K Rubarth, A Koch, P Vajkoczy, G Acker Tumor-Associated Microglia/Macrophages as a Predictor for Survival in Glioblastoma and Temozolomide-Induced Changes in CXCR2 Signaling with New Resistance Overcoming Strategy by Combination Therapy International Journal of Molecular Sciences, 2021-10-16;22(20):. 2021-10-16 [PMID: 34681839] (IHC, Human)	IHC	Human
S Padmanabha, B Gaire, Y Zou, MM Uddin, D DeLeon, I Vancurova IFNgamma induces JAK1/STAT1/p65 NFkappaB-dependent interleukin-8 expression in ovarian cancer cells, resulting in their increased migration The international journal of biochemistry & cell biology, 2021-10-06;141(0):106093. 10/6/2021 [PMID: 34626802]
Q Hou, S Chen, Q An, B Li, Y Fu, Y Luo Extracellular Hsp90alpha Promotes Tumor Lymphangiogenesis and Lymph Node Metastasis in Breast Cancer International Journal of Molecular Sciences, 2021-07-20;22(14):. 2021-07-20 [PMID: 34299365] (Co-Immunoprecipitation, ICC, IHC, Western Blot, Human)	Co-Immunoprecipitation, ICC, IHC, Western Blot	Human
S Gonçalves, K Yin, Y Ito, A Chan, I Olan, S Gough, L Cassidy, E Serrao, S Smith, A Young, M Narita, M Hoare COX2 regulates senescence secretome composition and senescence surveillance through PGE2 Cell Reports, 2021-03-16;34(11):108860. 2021-03-16 [PMID: 33730589] (ICC, Western Blot, Human)	ICC, Western Blot	Human
Suyanee Thongchot, Pranisa Jamjuntra, Suwanit Therasakvichya, Malee Warnnissorn, Alessandra Ferraresi, Peti Thuwajit et al. Interleukin‑8 released by cancer‑associated fibroblasts attenuates the autophagy and promotes the migration of ovarian cancer cells International Journal of Oncology 3/1/2021 [PMID: 33649784]
G Kaufman, D Skrtic N-Acetyl Cysteine Modulates the Inflammatory and Oxidative Stress Responses of Rescued Growth-Arrested Dental Pulp Microtissues Exposed to TEGDMA in ECM Int J Mol Sci, 2020-10-03;21(19):. 10/3/2020 [PMID: 33023018]
H Israelov, O Ravid, D Atrakchi, D Rand, S Elhaik, Y Bresler, R Twitto-Gre, L Omesi, S Liraz-Zalt, F Gosselet, M Schnaider, I Cooper Caspase-1 has a critical role in blood-brain barrier injury and its inhibition contributes to multifaceted repair J Neuroinflammation, 2020-09-09;17(1):267. 2020-09-09 [PMID: 32907600] (Neutralization, Human)	Neutralization	Human
S Abouelasra, M De Bondt, N Berghmans, M Gouwy, VLS de Oliveir, SC Oliveira, FA Amaral, P Proost, J Van Damme, S Struyf, M De Buck Biological Characterization of Commercial Recombinantly Expressed Immunomodulating Proteins Contaminated with Bacterial Products in the Year 2020: The SAA3 Case Mediators Inflamm., 2020-07-06;2020(0):6087109. 7/6/2020 [PMID: 32694927]
Ravi Holani, Anshu Babbar, Graham A. D. Blyth, Fernando Lopes, Humberto Jijon, Derek M. McKay et al. Cathelicidin-mediated lipopolysaccharide signaling via intracellular TLR4 in colonic epithelial cells evokes CXCL8 production Gut Microbes 11/9/2020 [PMID: 32658599]
Juan Antonio Fafián-Labora, Jose Antonio Rodríguez-Navarro, Ana O’Loghlen Small Extracellular Vesicles Have GST Activity and Ameliorate Senescence-Related Tissue Damage Cell Metabolism 7/7/2020 [PMID: 32574561]
H Kikuchi, N Maishi, DA Annan, M Towfik Ala, R Ibrahim Ha, M Sato, M Morimoto, R Takeda, K Ishizuka, R Matsumoto, T Akino, K Tsuchiya, T Abe, T Osawa, N Miyajima, S Maruyama, T Harabayash, M Azuma, K Yamashiro, K Ameda, A Kashiwagi, Y Matsuno, Y Hida, N Shinohara, K Hida Chemotherapy-induced IL-8 upregulates MDR1/ABCB1 in tumor blood vessels and results in unfavorable outcome Cancer Res., 2020-06-14;0(0):. 2020-06-14 [PMID: 32536602] (IHC, Neutralization, Human)	IHC, Neutralization	Human
Sara Abouelasrar Salama, Mirre De Bondt, Mieke De Buck, Nele Berghmans, Paul Proost, Vivian Louise Soares Oliveira et al. Serum Amyloid A1 (SAA1) Revisited: Restricted Leukocyte-Activating Properties of Homogeneous SAA1 Frontiers in Immunology 5/14/2020 [PMID: 32477346]
Katarzyna Bogucka, Malvika Pompaiah, Federico Marini, Harald Binder, Gregory Harms, Manuel Kaulich et al. ERK3/MAPK6 controls IL-8 production and chemotaxis eLife 4/21/2020 [PMID: 32314963]
M Dietachmay, A Rathakrish, O Karpiuk, F von Zweydo, T Engleitner, V Fernández-, P Schenk, M Ueffing, R Rad, M Eilers, CJ Gloeckner, K Clemm von, F Bassermann Antagonistic activities of CDC14B and CDK1 on USP9X regulate WT1-dependent mitotic transcription and survival Nat Commun, 2020-03-09;11(1):1268. 3/9/2020 [PMID: 32152317]
Q Ji, L Zhou, H Sui, L Yang, X Wu, Q Song, R Jia, R Li, J Sun, Z Wang, N Liu, Y Feng, X Sun, G Cai, Y Feng, J Cai, Y Cao, G Cai, Y Wang, Q Li Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation Nat Commun, 2020-03-05;11(1):1211. 2020-03-05 [PMID: 32139701] (Neutralization, Human)	Neutralization	Human
Sara Abouelasrar Salama, Mieke Gouwy, Alexandra De Zutter, Noëmie Pörtner, Lotte Vanbrabant, Nele Berghmans et al. Induction of Chemokines by Hepatitis C Virus Proteins: Synergy of the Core Protein with Interleukin-1 beta and Interferon-gamma in Liver Bystander Cells Journal of Interferon & Cytokine Research 4/1/2020 [PMID: 32031878]
LM Ashander, S Lie, Y Ma, E Rochet, JM Washington, JM Furtado, B Appukuttan, JR Smith Neutrophil Activities in Human Ocular Toxoplasmosis: An In Vitro Study With Human Cells Invest. Ophthalmol. Vis. Sci., 2019-11-01;60(14):4652-4660. 2019-11-01 [PMID: 31743940] (Neutralization, Human)	Neutralization	Human
R Eyre, DG Alférez, A Santiago-G, K Spence, JC McConnell, C Hart, BM Simões, D Lefley, C Tulotta, J Storer, A Gurney, N Clarke, M Brown, SJ Howell, AH Sims, G Farnie, PD Ottewell, RB Clarke Microenvironmental IL1beta promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling Nat Commun, 2019-11-01;10(1):5016. 2019-11-01 [PMID: 31676788] (Neutralization, Human)	Neutralization	Human
A Schulz, L Jiang, L de Vor, M Ehrström, F Wermeling, L Eidsmo, K Melican Neutrophil Recruitment to Noninvasive MRSA at the Stratum Corneum of Human Skin Mediates Transient Colonization Cell Rep, 2019-10-29;29(5):1074-1081.e5. 2019-10-29 [PMID: 31665625] (Blocking, Human)	Blocking	Human
R Lamichhane, M Schneider, SM de la Harp, TWR Harrop, RF Hannaway, PK Dearden, JR Kirman, JDA Tyndall, AJ Vernall, JE Ussher TCR- or Cytokine-Activated CD8+ Mucosal-Associated Invariant T Cells Are Rapid Polyfunctional Effectors That Can Coordinate Immune Responses Cell Rep, 2019-09-17;28(12):3061-3076.e5. 2019-09-17 [PMID: 31533031] (Bioassay, Human)	Bioassay	Human
Shuvasree SenGupta, Madhavi J Rane, Silvia M Uriarte, Cassandra Woolley, Thomas C Mitchell Human neutrophils depend on extrinsic factors produced by monocytes for their survival response to TLR4 stimulation Innate Immunity 11/1/2019 [PMID: 31480890]
Alejandro L. Antonia, Kyle D. Gibbs, Esme D. Trahair, Kelly J. Pittman, Amelia T. Martin, Benjamin H. Schott et al. Pathogen Evasion of Chemokine Response Through Suppression of CXCL10 Frontiers in Cellular and Infection Microbiology 8/7/2019 [PMID: 31440475]
Anita Guequén, Patricia Zamorano, Francisco Córdova, Tania Koning, Angelo Torres, Pamela Ehrenfeld et al. Interleukin-8 Secreted by Glioblastoma Cells Induces Microvascular Hyperpermeability Through NO Signaling Involving S-Nitrosylation of VE-Cadherin and p120 in Endothelial Cells Frontiers in Physiology 8/8/2019 [PMID: 31440166]
M Borghesan, J Fafián-Lab, O Eleftheria, P Carpintero, M Paez-Ribes, G Vizcay-Bar, A Swisa, D Kolodkin-G, P Ximénez-Em, R Lowe, B Martín-Mar, H Peinado, J Muñoz, RA Fleck, Y Dor, I Ben-Porath, A Vossenkamp, D Muñoz-Espi, A O'Loghlen Small Extracellular Vesicles Are Key Regulators of Non-cell Autonomous Intercellular Communication in Senescence via the Interferon Protein IFITM3 Cell Rep, 2019-06-25;27(13):3956-3971.e6. 2019-06-25 [PMID: 31242426] (ICC, Western Blot, Human)	ICC, Western Blot	Human
DP Muñoz, SM Yannone, A Daemen, Y Sun, F Vakar-Lope, M Kawahara, AM Freund, F Rodier, JD Wu, PY Desprez, DH Raulet, PS Nelson, LJ van 't Vee, J Campisi, JP Coppé Targetable mechanisms driving immunoevasion of persistent senescent cells link chemotherapy-resistant cancer to aging JCI Insight, 2019-06-11;5(0):. 2019-06-11 [PMID: 31184599] (IHC, Human)	IHC	Human
L Miarka, C Hauser, O Helm, D Holdhof, S Beckinger, JH Egberts, JP Gundlach, L Lenk, S Rahn, W Mikulits, A Trauzold, S Sebens The Hepatic Microenvironment and TRAIL-R2 Impact Outgrowth of Liver Metastases in Pancreatic Cancer after Surgical Resection Cancers (Basel), 2019-05-29;11(6):. 2019-05-29 [PMID: 31146405] (Neutralization, Human)	Neutralization	Human
Lynsey M. Whilding, Leena Halim, Benjamin Draper, Ana C. Parente-Pereira, Tomasz Zabinski, David Marc Davies et al. CAR T-Cells Targeting the Integrin alpha v beta 6 and Co-Expressing the Chemokine Receptor CXCR2 Demonstrate Enhanced Homing and Efficacy against Several Solid Malignancies Cancers (Basel) 5/14/2019 [PMID: 31091832]
C Ling, K Nishimoto, Z Rolfs, LM Smith, BL Frey, NV Welham Differentiated fibrocytes assume a functional mesenchymal phenotype with regenerative potential Sci Adv, 2019-05-08;5(5):eaav7384. 2019-05-08 [PMID: 31086819] (Bioassay, Rat)	Bioassay	Rat
A Krishnamur, AJ Ytterberg, M Sun, K Sakuraba, J Steen, V Joshua, NK Tarasova, V Malmström, H Wähämaa, B Réthi, AI Catrina Citrullination Controls Dendritic Cell Transdifferentiation into Osteoclasts J. Immunol., 2019-04-24;0(0):. 4/24/2019 [PMID: 31019059]
EP Reeves, DM Dunlea, K McQuillan, CA O'Dwyer, TP Carroll, R Saldova, PR Akepati, MR Wormald, OJ McElvaney, V Shutchaida, M Henry, P Meleady, J Keenan, DC Liberti, DN Kotton, PM Rudd, AA Wilson, NG McElvaney Circulating Truncated Alpha-1 Antitrypsin Glycoprotein in Patient Plasma Retains Anti-Inflammatory Capacity J. Immunol., 2019-02-22;0(0):. 2019-02-22 [PMID: 30796179] (Binding Assay, Human)	Binding Assay	Human
CN Como, AN Bubak, AM Blackmon, D Jones, NH Mueller, R Davidson, MA Nagel Varicella Zoster Virus Induces Differential Cell-Type Specific Responses in Human Corneal Epithelial Cells and Keratocytes Invest. Ophthalmol. Vis. Sci., 2019-02-01;60(2):704-711. 2019-02-01 [PMID: 30786281] (Neutralization, Human)	Neutralization	Human
J Zhang, H Li, Q Wu, Y Chen, Y Deng, Z Yang, L Zhang, B Liu Tumoral NOX4 recruits M2 tumor-associated macrophages via ROS/PI3K signaling-dependent various cytokine production to promote NSCLC growth Redox Biol, 2019-02-06;22(0):101116. 2019-02-06 [PMID: 30769285] (Neutralization, Human)	Neutralization	Human
Mirella Georgouli, Cecilia Herraiz, Eva Crosas-Molist, Bruce Fanshawe, Oscar Maiques, Anna Perdrix et al. Regional Activation of Myosin II in Cancer Cells Drives Tumor Progression via a Secretory Cross-Talk with the Immune Microenvironment Cell 2/7/2019 [PMID: 30712866]
MJ Domínguez-, E Armas-Gonz, A Herrera-Ga, M Arce-Franc, M Feria, M Vicente-Ma, A Martínez-R, F Sánchez-Ma, F Díaz-Gonzá L-selectin expression is regulated by CXCL8-induced reactive oxygen species produced during human neutrophil rolling Eur. J. Immunol., 2018-12-05;0(0):. 2018-12-05 [PMID: 30443903] (Neutralization, Human)	Neutralization	Human
Manja Idorn, Signe Koggersbøl Skadborg, Lauge Kellermann, Hólmfrídur Rósa Halldórsdóttir, Gitte Holmen Olofsson, Özcan Met et al. Chemokine receptor engineering of T cells with CXCR2 improves homing towards subcutaneous human melanomas in xenograft mouse model OncoImmunology 4/18/2018 [PMID: 30221044]
SE Logue, EP McGrath, P Cleary, S Greene, K Mnich, A Almanza, E Chevet, RM Dwyer, A Oommen, P Legembre, F Godey, EC Madden, B Leuzzi, J Obacz, Q Zeng, JB Patterson, R Jäger, AM Gorman, A Samali Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy Nat Commun, 2018-08-15;9(1):3267. 2018-08-15 [PMID: 30111846] (Neutralization, Human)	Neutralization	Human
B Gril, AN Paranjape, S Woditschka, E Hua, EL Dolan, J Hanson, X Wu, W Kloc, E Izycka-Swi, R Duchnowska, R P?ksa, W Biernat, J Jassem, N Nayyar, PK Brastianos, OM Hall, CJ Peer, WD Figg, GT Pauly, C Robinson, S Difilippan, E Bialecki, P Metellus, JP Schneider, PS Steeg Reactive astrocytic S1P3 signaling modulates the blood-tumor barrier in brain metastases Psychoneuroendocrinology, 2018-07-13;9(1):2705. 2018-07-13 [PMID: 30006619] (Neutralization, Human)	Neutralization	Human
Bianca Cioni, Ekaterina Nevedomskaya, Monique H. M. Melis, Johan van Burgsteden, Suzan Stelloo, Emma Hodel et al. Loss of androgen receptor signaling in prostate cancer‐associated fibroblasts (CAFs) promotes CCL2‐ and CXCL8‐mediated cancer cell migration Molecular Oncology 8/1/2018 [PMID: 29808619]
Jie Ji, Swapna Upadhyay, Xiaomiao Xiong, Maria Malmlöf, Thomas Sandström, Per Gerde et al. Multi-cellular human bronchial models exposed to diesel exhaust particles: assessment of inflammation, oxidative stress and macrophage polarization Particle and Fibre Toxicology 12/1/2018 [PMID: 29716632]
A Kumar, M Cherukumil, SH Mahmoudpou, K Brand, OR Bandapalli ShRNA-mediated knock-down of CXCL8 inhibits tumor growth in colorectal liver metastasis Biochem. Biophys. Res. Commun., 2018-04-23;0(0):. 2018-04-23 [PMID: 29679563] (Western Blot, Human)	Western Blot	Human
A Micera, A Di Zazzo, G Esposito, R Longo, W Foulsham, R Sacco, R Sgrulletta, S Bonini Age-Related Changes to Human Tear Composition Invest. Ophthalmol. Vis. Sci., 2018-04-01;59(5):2024-2031. 2018-04-01 [PMID: 29677365] (Western Blot, Human)	Western Blot	Human
Q Liu, A Li, S Yu, S Qin, N Han, RG Pestell, X Han, K Wu DACH1 antagonizes CXCL8 to repress tumorigenesis of lung adenocarcinoma and improve prognosis J Hematol Oncol, 2018-04-10;11(1):53. 2018-04-10 [PMID: 29636079] (Bioassay, Human)	Bioassay	Human
F Melo-Gonza, TM Fenton, C Forss, C Smedley, A Goenka, AS MacDonald, DJ Thornton, MA Travis Intestinal mucin activates human dendritic cells and IL-8 production in a glycan-specific manner J. Biol. Chem., 2018-03-26;0(0):. 2018-03-26 [PMID: 29581231] (Neutralization, Human)	Neutralization	Human
Pietrovito L, Leo A, Gori V et al. Bone marrow-derived mesenchymal stem cells promote invasiveness and transendothelial migration of osteosarcoma cells via a mesenchymal to amoeboid transition. Mol Oncol. 3/8/2018 [PMID: 29517849]
X Sun, B Shi, H Zheng, L Min, J Yang, X Li, X Liao, W Huang, M Zhang, S Xu, Z Zhu, H Cui, X Liu Senescence-associated secretory factors induced by cisplatin in melanoma cells promote non-senescent melanoma cell growth through activation of the ERK1/2-RSK1 pathway Cell Death Dis, 2018-02-15;9(3):260. 2/15/2018 [PMID: 29449532]
Y Su, P Wang, H Shen, Z Sun, C Xu, G Li, T Tong, J Chen Protein kinase D1-mediated classical protein secretory pathway regulates oncogene Ras-induced senescent response J. Cell. Sci., 2018-03-16;0(0):. 3/16/2018 [PMID: 29420297]
S Arl?er Endothelial cell leptin receptors, leptin and interleukin-8 in the pathogenesis of preeclampsia: An in-vitro study Turk J Obstet Gynecol, 2017-12-30;14(4):220-227. 2017-12-30 [PMID: 29379664] (Western Blot, Human)	Western Blot	Human
Y Uchino, AM Woodward, J Mauris, K Peterson, P Verma, UJ Nilsson, J Rajaiya, P Argüeso Galectin-3 is an amplifier of the interleukin-1?-mediated inflammatory response in corneal keratinocytes Immunology, 2018-02-15;0(0):. 2018-02-15 [PMID: 29359328] (Western Blot, Human)	Western Blot	Human
S di Martino, CA Amoreo, B Nuvoli, R Galati, S Strano, F Facciolo, G Alessandri, HI Pass, G Ciliberto, G Blandino, R De Maria, M Cioce HSP90 inhibition alters the chemotherapy-driven rearrangement of the oncogenic secretome Oncogene, 2018-01-09;0(0):. 2018-01-09 [PMID: 29311642] (Inhibition, Human)	Inhibition	Human
Vinit Kumar, Laxminarasimha Donthireddy, Douglas Marvel, Thomas Condamine, Fang Wang, Sergio Lavilla-Alonso et al. Cancer-Associated Fibroblasts Neutralize the Anti-tumor Effect of CSF1 Receptor Blockade by Inducing PMN-MDSC Infiltration of Tumors Cancer Cell 11/1/2017 [PMID: 29136508]
Sugong Chen, Robert C. Fisher, Steven Signs, L. Alex Molina, Anitha K. Shenoy, Maria-Cecilia Lopez et al. Inhibition of PI3K/Akt/mTOR signaling in PI3KR2-overexpressing colon cancer stem cells reduces tumor growth due to apoptosis Oncotarget 8/1/2017 [PMID: 28881576]
J Ikari, AJ Nelson, J Obaid, A Giron-Mart, K Ikari, F Makino, S Iwasawa, Y Gunji, M Farid, X Wang, H Basma, D Demeo, C Feghali-Bo, O Holz, K Rabe, X Liu, SI Rennard Reduced microRNA-503 expression augments lung fibroblast VEGF production in chronic obstructive pulmonary disease PLoS ONE, 2017-09-07;12(9):e0184039. 2017-09-07 [PMID: 28880936] (ELISA Development (Capture), Human)	ELISA Development (Capture)	Human
MM White, P Geraghty, E Hayes, S Cox, W Leitch, B Alfawaz, GM Lavelle, OJ McElvaney, R Flannery, J Keenan, P Meleady, M Henry, M Clynes, C Gunaratnam, NG McElvaney, EP Reeves Neutrophil Membrane Cholesterol Content is a Key Factor in Cystic Fibrosis Lung Disease EBioMedicine, 2017-08-16;23(0):173-184. 2017-08-16 [PMID: 28835336] (ELISA Development (Capture), Human)	ELISA Development (Capture)	Human
B Tian, A Al-Moujahe, P Bouzika, Y Hu, S Notomi, P Tsoka, JW Miller, H Lin, DG Vavvas Atorvastatin Promotes Phagocytosis and Attenuates Pro-Inflammatory Response in Human Retinal Pigment Epithelial Cells Sci Rep, 2017-05-24;7(1):2329. 2017-05-24 [PMID: 28539592] (Western Blot, Human)	Western Blot	Human
Y Wang, J Liu, Q Jiang, J Deng, F Xu, X Chen, F Cheng, Y Zhang, Y Yao, Z Xia, X Xu, X Su, M Huang, L Dai, Y Yang, S Zhang, D Yu, RC Zhao, Y Wei, H Deng Human adipose-derived mesenchymal stem cell-secreted CXCL1 and CXCL8 facilitate breast tumor growth by promoting angiogenesis Stem Cells, 2017-06-05;0(0):. 2017-06-05 [PMID: 28514506] (Neutralization, Human)	Neutralization	Human
J Liu, G Song, X Lin, X Pang, T Meng Upregulated unique long 16 binding protein 1 detected in preeclamptic placenta affects human extravillous trophoblast cell line (HTR-8/SVneo) invasion by modulating the function of uterine natural killer cells Exp Ther Med, 2017-02-21;13(4):1447-1455. 2017-02-21 [PMID: 28413491] (Functional Assay, Human)	Functional Assay	Human
HB Song, HO Jun, JH Kim, YH Lee, MH Choi, JH Kim Disruption of outer blood-retinal barrier by Toxoplasma gondii-infected monocytes is mediated by paracrinely activated FAK signaling PLoS ONE, 2017-04-13;12(4):e0175159. 2017-04-13 [PMID: 28406972] (Neutralization, Human)	Neutralization	Human
CM Henry, SJ Martin Caspase-8 Acts in a Non-enzymatic Role as a Scaffold for Assembly of a Pro-inflammatory FADDosome Complex upon TRAIL Stimulation Mol. Cell, 2017-02-16;65(4):715-729.e5. 2017-02-16 [PMID: 28212752] (ICC, Human)	ICC	Human
HR Gatla, Y Zou, MM Uddin, B Singha, P Bu, A Vancura, I Vancurova Histone Deacetylase (HDAC) Inhibition Induces I?B Kinase (IKK)-dependent Interleukin-8/CXCL8 Expression in Ovarian Cancer Cells J. Biol. Chem., 2017-02-06;292(12):5043-5054. 2017-02-06 [PMID: 28167529] (Neutralization, Human)	Neutralization	Human
Human pancreatic cancer cells induce a MyD88-dependent stromal response to promote a tumor-tolerant immune microenvironment Cancer Res., 2016-11-18;0(0):. 2016-11-18 [PMID: 27864347] (Bioassay, Human)	Bioassay	Human
Yuh-Lin Wu Novel augmentation by bufalin of protein kinase C-induced cyclooxygenase-2 and IL-8 production in human breast cancer cells Innate Immun, 2016-11-30;0(0):. 2016-11-30 [PMID: 27821648] (Bioassay, Human)	Bioassay	Human
Charli Dominguez, Kwong-Yok Tsang, Claudia Palena Short-term EGFR blockade enhances immune-mediated cytotoxicity of EGFR mutant lung cancer cells: rationale for combination therapies Cell Death & Disease 9/29/2016 [PMID: 27685624]
Growth Hormone Releasing Peptide-2 Attenuation of Protein Kinase C-Induced Inflammation in Human Ovarian Granulosa Cells Int J Mol Sci, 2016-08-19;17(8):. 2016-08-19 [PMID: 27548147] (Western Blot, Human)	Western Blot	Human
M Hoare, Y Ito, TW Kang, MP Weekes, NJ Matheson, DA Patten, S Shetty, AJ Parry, S Menon, R Salama, R Antrobus, K Tomimatsu, W Howat, PJ Lehner, L Zender, M Narita NOTCH1 mediates a switch between two distinct secretomes during senescence Nat. Cell Biol, 2016-08-15;18(9):979-92. 2016-08-15 [PMID: 27525720] (Western Blot, Human)	Western Blot	Human
Tsr Chemoreceptor Interacts With IL-8 Provoking E. coli Transmigration Across Human Lung Epithelial Cells Sci Rep, 2016-08-10;6(0):31087. 2016-08-10 [PMID: 27506372] (Immunoprecipitation, Bacteria - E. Coli)	Immunoprecipitation	Bacteria - E. Coli
Britt-Marie Sundblad, Britt-Marie Sundblad, Bettina Levänen, Bettina Midander, Anneli Midander, Anneli Julander et al. Extracellular cadmium in the bronchoalveolar space of long-term tobacco smokers with and without COPD and its association with inflammation International Journal of Chronic Obstructive Pulmonary Disease 6/9/2016 [PMID: 27274222]
Romaine I. Fernando, Duane H. Hamilton, Charli Dominguez, Justin M. David, Kristen K. McCampbell, Claudia Palena IL-8 signaling is involved in resistance of lung carcinoma cells to erlotinib Oncotarget 7/5/2106 [PMID: 27248176]
Amy Sinclair, Laura Park, Mansi Shah, Mark Drotar, Simon Calaminus, Lisa E. M. Hopcroft et al. CXCR2 and CXCL4 regulate survival and self-renewal of hematopoietic stem/progenitor cells Blood 7/21/2016 [PMID: 27222476]
Z Jing, H Xu, X Chen, Q Zhong, J Huang, Y Zhang, W Guo, Z Yang, S Ding, P Chen, Z Huang The Proton-Sensing G-Protein Coupled Receptor GPR4 Promotes Angiogenesis in Head and Neck Cancer PLoS ONE, 2016-04-14;11(4):e0152789. 2016-04-14 [PMID: 27078157] (Neutralization, Human)	Neutralization	Human
Stefano Di Santo, Anna-Lena Fuchs, Ramesh Periasamy, Stefanie Seiler, Hans Rudolf Widmer The Cytoprotective Effects of Human Endothelial Progenitor Cell-Conditioned Medium against an Ischemic Insult Are Not Dependent on VEGF and IL-8 Cell Transplantation 4/1/2016 [PMID: 26776768]
Gao Y, Zhou Z, Lu S, Huang X, Zhang C, Jiang R, Yao A, Sun B, Wang X Chemokine CCL15 Mediates Migration of Human Bone Marrow-Derived Mesenchymal Stem Cells Toward Hepatocellular Carcinoma. Stem Cells, 2016-01-13;34(4):1112-22. 2016-01-13 [PMID: 26763650] (Neutralization, Human)	Neutralization	Human
Akilan Krishnamurthy, Vijay Joshua, Aase Haj Hensvold, Tao Jin, Meng Sun, Nancy Vivar et al. Identification of a novel chemokine-dependent molecular mechanism underlying rheumatoid arthritis-associated autoantibody-mediated bone loss Annals of the Rheumatic Diseases 4/1/2016 [PMID: 26612338]
Pauline Muscat, Karessa Mercado, Kathryn Payne, Hardip Chahal, Graham Jones PHF11 expression and cellular distribution is regulated by the Toll-Like Receptor 3 Ligand Polyinosinic:Polycytidylic Acid in HaCaT keratinocytes BMC Immunology 12/1/2015 [PMID: 26573531]
Bernard Dib, Haijiang Lin, Daniel E. Maidana, Bo Tian, John B. Miller, Peggy Bouzika et al. Mitochondrial DNA has a pro-inflammatory role in AMD Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 11/1/2015 [PMID: 26305120]
Chen L, Min L, Wang X, Zhao J, Chen H, Qin J, Chen W, Shen Z, Tang Z, Gan Q, Ruan Y, Sun Y, Qin X, Gu J Loss of RACK1 Promotes Metastasis of Gastric Cancer by Inducing a miR-302c/IL8 Signaling Loop. Cancer Res, 2015-07-21;75(18):3832-41. 2015-07-21 [PMID: 26199092] (Neutralization, Human, Mouse)	Neutralization	Human, Mouse
Mahito Sadaie, Christian Dillon, Masako Narita, Masashi Narita, Andrew R J Young, Claire J Cairney et al. Cell-based screen for altered nuclear phenotypes reveals senescence progression in polyploid cells after Aurora kinase B inhibition Molecular Biology of the Cell 9/1/2015 [PMID: 26133385]
Maria Hårdstedt, Susanne Lindblom, Alex Karlsson-Parra, Bo Nilsson, Olle Korsgren Characterization of Innate Immunity in an Extended Whole Blood Model of Human Islet Allotransplantation Cell Transplantation 3/1/2016 [PMID: 26084381]
Takeuchi S, Baghdadi M, Tsuchikawa T, Wada H, Nakamura T, Abe H, Nakanishi S, Usui Y, Higuchi K, Takahashi M, Inoko K, Sato S, Takano H, Shichinohe T, Seino K, Hirano S Chemotherapy-Derived Inflammatory Responses Accelerate the Formation of Immunosuppressive Myeloid Cells in the Tissue Microenvironment of Human Pancreatic Cancer. Cancer Res, 2015-05-07;75(13):2629-40. 2015-05-07 [PMID: 25952647] (Neutralization, Human)	Neutralization	Human
McElvaney O, O'Reilly N, White M, Lacey N, Pohl K, Gerlza T, Bergin D, Kerr H, McCarthy C, O'Brien M, Adage T, Kungl A, Reeves E, McElvaney N The effect of the decoy molecule PA401 on CXCL8 levels in bronchoalveolar lavage fluid of patients with cystic fibrosis. Mol Immunol, 2014-11-02;63(2):550-8. 2014-11-02 [PMID: 25453468] (Bioassay, Human)	Bioassay	Human
Voltolini C, Battersby S, Novembri R, Torricelli M, Severi F, Petraglia F, Norman J Urocortin 2 role in placental and myometrial inflammatory mechanisms at parturition. Endocrinology, 2014-11-26;156(2):670-9. 2014-11-26 [PMID: 25426872] (ELISA Development (Capture), Human)	ELISA Development (Capture)	Human
Elizabeth England, Philip Newton, Frances Neal, Lisa Kitching, Caroline Colley, Christine J. Rossant Application of the Mirrorball High-Sensitivity Cytometer to Multiplexed Assays for Antibody Drug Discovery J Biomol Screen 4/1/2015 [PMID: 25381256]
Gouwy M, De Buck M, Portner N, Opdenakker G, Proost P, Struyf S, Van Damme J Serum amyloid A chemoattracts immature dendritic cells and indirectly provokes monocyte chemotaxis by induction of cooperating CC and CXC chemokines. Eur J Immunol, 2014-12-01;45(1):101-12. 2014-12-01 [PMID: 25345597] (Neutralization, Human)	Neutralization	Human
Yijun Hu, Haijiang Lin, Bernard Dib, Alp Atik, Peggy Bouzika, Christopher Lin et al. Cholesterol crystals induce inflammatory cytokines expression in a human retinal pigment epithelium cell line by activating the NF-kappa B pathway Discov Med 8/26/2015 [PMID: 25091484]
Kuravi S, McGettrick H, Satchell S, Saleem M, Harper L, Williams J, Rainger G, Savage C Podocytes regulate neutrophil recruitment by glomerular endothelial cells via IL-6-mediated crosstalk. J Immunol, 2014-05-28;193(1):234-43. 2014-05-28 [PMID: 24872191] (Neutralization, Human)	Neutralization	Human
Moelants , Eva A V, Loozen , Gitte, Mortier , Anneleen, Martens , Erik, Opdenakker , Ghislain, Mizgalska , Danuta, Szmigielski , Borys, Potempa , Jan, Van Damme , Jo, Teughels , Wim, Proost , Paul Citrullination and proteolytic processing of chemokines by Porphyromonas gingivalis. Infect Immun, 2014-03-31;82(6):2511-9. 2014-03-31 [PMID: 24686061] (ELISA Development (Detection), Bacteria - Porphyromonas gingivalis)	ELISA Development (Detection)	Bacteria - Porphyromonas gingivalis
Mamik M, Ghorpade A Chemokine CXCL8 promotes HIV-1 replication in human monocyte-derived macrophages and primary microglia via nuclear factor-kappaB pathway. PLoS ONE, 2014-03-24;9(3):e92145. 2014-03-24 [PMID: 24662979] (Bioassay, Human)	Bioassay	Human
Pamela H.S. Tan, Su Shin Chia, Siew Lok Toh, James C.H. Goh, Saminathan Suresh Nathan The Dominant Role of IL-8 as an Angiogenic Driver in a Three-Dimensional Physiological Tumor Construct for Drug Testing Tissue Engineering Part A 6/1/2014 [PMID: 24372172]
Windheim M, Hansen B Interleukin-1-induced activation of the small GTPase Rac1 depends on receptor internalization and regulates gene expression. Cell Signal, 2013-09-28;26(1):49-55. 2013-09-28 [PMID: 24080160] (Western Blot, Human)	Western Blot	Human
Khanna , P, Chung , C-Y, Neves , R I, Robertson , G P, Dong , C CD82/KAI expression prevents IL-8-mediated endothelial gap formation in late-stage melanomas. Oncogene, 2013-07-22;33(22):2898-908. 2013-07-22 [PMID: 23873025] (ELISA Development (Capture), Western Blot, Human)	ELISA Development (Capture), Western Blot	Human
Frank Götschel, Daniela Berg, Wolfgang Gruber, Christian Bender, Markus Eberl, Myriam Friedel et al. Synergism between Hedgehog-GLI and EGFR Signaling in Hedgehog-Responsive Human Medulloblastoma Cells Induces Downregulation of Canonical Hedgehog-Target Genes and Stabilized Expression of GLI1 PLoS ONE 6/10/2013 [PMID: 23762360]
Nakajima N, Van Tin N, Sato Y, Thach H, Katano H, Diep P, Kumasaka T, Thuy N, Hasegawa H, San L, Kawachi S, Liem N, Suzuki K, Sata T Pathological study of archival lung tissues from five fatal cases of avian H5N1 influenza in Vietnam. Mod Pathol, 2012-11-23;26(3):357-69. 2012-11-23 [PMID: 23174938] (IHC-P, Human)	IHC-P	Human
Antonia Patsialou, Yarong Wang, Juan Lin, Kathleen Whitney, Sumanta Goswami, Paraic A Kenny et al. Selective gene-expression profiling of migratory tumor cells in vivo predicts clinical outcome in breast cancer patients Breast Cancer Research 10/31/2012 [PMID: 23113900]
Macrophages induce differentiation of plasma cells through CXCL10/IP-10. J. Exp. Med., 2012-09-17;209(10):1813-23. 2012-09-17 [PMID: 22987802] (Neutralization, Human)	Neutralization	Human
Gelderblom M, Weymar A, Bernreuther C, Velden J, Arunachalam P, Steinbach K, Orthey E, Arumugam T, Leypoldt F, Simova O, Thom V, Friese M, Prinz I, Holscher C, Glatzel M, Korn T, Gerloff C, Tolosa E, Magnus T Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke. Blood, 2012-09-13;120(18):3793-802. 2012-09-13 [PMID: 22976954] (IHC-P, Human)	IHC-P	Human
Nicolaidou V, Wong MM, Redpath AN Monocytes Induce STAT3 Activation in Human Mesenchymal Stem Cells to Promote Osteoblast Formation. PLoS ONE, 2012-07-03;7(7):e39871. 2012-07-03 [PMID: 22802946] (Neutralization, Human)	Neutralization	Human
Meda C, Molla F, De Pizzol M Semaphorin 4A exerts a proangiogenic effect by enhancing vascular endothelial growth factor-A expression in macrophages. J. Immunol., 2012-03-21;188(8):4081-92. 2012-03-21 [PMID: 22442441] (Neutralization, Human)	Neutralization	Human
Sahlander K, Larsson K, Palmberg L Daily exposure to dust alters innate immunity. PLoS ONE, 2012-02-15;7(2):e31646. 2012-02-15 [PMID: 22355383] (ELISA Development, Human)	ELISA Development	Human
Bellini A, Marini MA, Bianchetti L, Barczyk M, Schmidt M, Mattoli S Interleukin (IL)-4, IL-13, and IL-17A differentially affect the profibrotic and proinflammatory functions of fibrocytes from asthmatic patients. Mucosal Immunol, 2011-12-21;5(2):140-9. 2011-12-21 [PMID: 22189956] (Neutralization, Human)	Neutralization	Human
Michael Lichtenauer, Michael Mildner, Konrad Hoetzenecker, Matthias Zimmermann, Bruno Karl Podesser, Wolfgang Sipos et al. Secretome of apoptotic peripheral blood cells (APOSEC) confers cytoprotection to cardiomyocytes and inhibits tissue remodelling after acute myocardial infarction: a preclinical study Basic Research in Cardiology 11/1/2011 [PMID: 21952733]
R Grepin, M Guyot, M Jacquin, J Durivault, E Chamorey, A Sudaka et al. Acceleration of clear cell renal cell carcinoma growth in mice following bevacizumab/Avastin treatment: the role of CXCL cytokines Oncogene 3/29/2012 [PMID: 21909141]
Zepp JA, Nold-Petry CA, Dinarello CA, Nold MF Protection from RNA and DNA viruses by IL-32. J. Immunol., 2011-02-23;186(7):4110-8. 2011-02-23 [PMID: 21346229] (Electrochemiluminescent Assay, Human)	Electrochemiluminescent Assay	Human
Chang Y, Al-Alwan L, Risse PA, Roussel L, Rousseau S, Halayko AJ, Martin JG, Hamid Q, Eidelman DH TH17 cytokines induce human airway smooth muscle cell migration. J. Allergy Clin. Immunol., 2011-02-22;127(4):1046-53.e1-2. 2011-02-22 [PMID: 21345484] (Neutralization, Human)	Neutralization	Human
Wei He, Leopoldo Luistro, Daisy Carvajal, Melissa Smith, Tom Nevins, Xuefeng Yin et al. High tumor levels of IL6 and IL8 abrogate preclinical efficacy of the gamma -secretase inhibitor, RO4929097 Molecular Oncology 6/1/2011 [PMID: 21315665]
Nora Theilacker, Eric E. Roller, Kristopher D. Barbee, Matthias Franzreb, Xiaohua Huang Multiplexed protein analysis using encoded antibody-conjugated microbeads Journal of The Royal Society Interface 8/7/2011 [PMID: 21247950]
Joanna Walker, Lucy Clare Smiley, David Ingram, Ann Roman Expression of human papillomavirus type 16 E7 is sufficient to significantly increase expression of angiogenic factors but is not sufficient to induce endothelial cell migration Virology 2/20/2011 [PMID: 21159359]
Kalliolias GD, Gordon RA, Ivashkiv LB Suppression of TNF-alpha and IL-1 signaling identifies a mechanism of homeostatic regulation of macrophages by IL-27. J. Immunol., 2010-10-22;185(11):7047-56. 2010-10-22 [PMID: 20971923] (ELISA Development, Human)	ELISA Development	Human
Guilloteau K, Paris I, Pedretti N, Boniface K, Juchaux F, Huguier V, Guillet G, Bernard FX, Lecron JC, Morel F Skin Inflammation Induced by the Synergistic Action of IL-17A, IL-22, Oncostatin M, IL-1alpha, and TNF-alpha Recapitulates Some Features of Psoriasis. J. Immunol., 2010-03-24;184(0):5263-70. 2010-03-24 [PMID: 20335534] (Neutralization, Human)	Neutralization	Human
Joanna L. Richens, Richard A. Urbanowicz, Rebecca Metcalf, Jonathan Corne, Paul O’Shea, Lucy Fairclough Quantitative Validation and Comparison of Multiplex Cytokine Kits J Biomol Screen 2010-06-01 [PMID: 20176857]
Joanna L. Richens, Richard A. Urbanowicz, Rebecca Metcalf, Jonathan Corne, Paul O’Shea, Lucy Fairclough Quantitative Validation and Comparison of Multiplex Cytokine Kits J Biomol Screen 2010-06-01 [PMID: 20176857]
Dipa Bhaumik, Gary K. Scott, Shiruyeh Schokrpur, Christopher K. Patil, Arturo V. Orjalo, Francis Rodier et al. MicroRNAs miR-146a/b negatively modulate the senescence-associated inflammatory mediators IL-6 and IL-8 ImpactJ 4/21/2009 [PMID: 20148189]
Dan Huang, Yan Ding, Ming Zhou, Brian I. Rini, David Petillo, Chao-Nan Qian et al. Interleukin-8 Mediates Resistance to Antiangiogenic Agent Sunitinib in Renal Cell Carcinoma Cancer Research 2/1/2010 [PMID: 20103651]
Reeves EP, Williamson M, Byrne B, Bergin DA, Smith SG, Greally P, O'Kennedy R, O'Neill SJ, McElvaney NG IL-8 dictates glycosaminoglycan binding and stability of IL-18 in cystic fibrosis. J. Immunol., 2009-12-21;184(3):1642-52. 2009-12-21 [PMID: 20026745] (Western Blot, Human)	Western Blot	Human
Filip Kukulski, Fethia Ben Ben Yebdri, Fariborz Bahrami, Michel Fausther, Alain Tremblay, Jean Sévigny Endothelial P2Y2 receptor regulates LPS-induced neutrophil transendothelial migration in vitro Molecular Immunology 2/1/2010 [PMID: 20022380]
Rodier F, Coppe JP, Patil CK, Hoeijmakers WA, Munoz DP, Raza SR, Freund A, Campeau E, Davalos AR, Campisi J Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion. Nat. Cell Biol., 2009-07-13;11(8):973-9. 2009-07-13 [PMID: 19597488] (ICC, Human)	ICC	Human
Hu H, Kwun J, Aizenstein BD, Knechtle SJ Noninvasive detection of acute and chronic injuries in human renal transplant by elevation of multiple cytokines/chemokines in urine. Transplantation, 2009-06-27;87(12):1814-20. 2009-06-27 [PMID: 19543058] (Antibody Array Development, Human)	Antibody Array Development	Human
Li Z, Alam S, Wang J, Sandstrom CS, Janciauskiene S, Mahadeva R Oxidized alpha1-antitrypsin stimulates the release of monocyte chemotactic protein-1 from lung epithelial cells: potential role in emphysema. Am. J. Physiol. Lung Cell Mol. Physiol., 2009-06-12;297(2):L388-400. 2009-06-12 [PMID: 19525388] (ELISA Development, Human)	ELISA Development	Human
Osei-Kumah A, Smith R, Clifton VL Maternal and cord plasma cytokine and chemokine profile in pregnancies complicated by asthma. Cytokine, 2008-07-17;43(2):187-93. 2008-07-17 [PMID: 18639465] (ELISA Development, Human)	ELISA Development	Human
Skov L, Beurskens FJ, Zachariae CO, Reitamo S, Teeling J, Satijn D, Knudsen KM, Boot EP, Hudson D, Baadsgaard O, Parren PW, van de Winkel JG IL-8 as antibody therapeutic target in inflammatory diseases: reduction of clinical activity in palmoplantar pustulosis. J. Immunol., 2008-07-01;181(1):669-79. 2008-07-01 [PMID: 18566434] (Neutralization, Human)	Neutralization	Human
Nold MF, Nold-Petry CA, Pott GB, Zepp JA, Saavedra MT, Kim SH, Dinarello CA Endogenous IL-32 controls cytokine and HIV-1 production. J. Immunol., 2008-07-01;181(1):557-65. 2008-07-01 [PMID: 18566422] (Electrochemiluminescent Assay, Human)	Electrochemiluminescent Assay	Human
Goczalik I, Ulbricht E, Hollborn M, Raap M, Uhlmann S, Weick M, Pannicke T, Wiedemann P, Bringmann A, Reichenbach A, Francke M Expression of CXCL8, CXCR1, and CXCR2 in neurons and glial cells of the human and rabbit retina. Invest. Ophthalmol. Vis. Sci., 2008-06-14;49(10):4578-89. 2008-06-14 [PMID: 18552386] (IHC-Fr, Human, Rabbit)	IHC-Fr	Human, Rabbit
Qui H, Ferrell EP, Nolan N, Phelps BH, Tabibiazar R, Whitney DH, Naelfski EA Fluorescence single-molecule counting assays for high-sensitivity detection of cytokines and chemokines. Clin. Chem., 2007-11-01;53(11):2010-2. 2007-11-01 [PMID: 18030696] (ELISA Development, Human)	ELISA Development	Human
Weindl G, Naglik JR, Kaesler S, Biedermann T, Hube B, Korting HC, Schaller M Human epithelial cells establish direct antifungal defense through TLR4-mediated signaling. J. Clin. Invest., 2007-12-01;117(12):3664-3672. 2007-12-01 [PMID: 17992260] (Neutralization, Human)	Neutralization	Human
Pfleger C, Schloot N, ter Veld F Effect of serum content and diluent selection on assay sensitivity and signal intensity in multiplex bead-based immunoassays. J. Immunol. Methods, 2007-10-22;329(1):214-8. 2007-10-22 [PMID: 17964594] (Luminex Development, Human)	Luminex Development	Human
Cheadle EJ, Riyad K, Subar D, Rothwell DG, Ashton G, Batha H, Sherlock DJ, Hawkins RE, Gilham DE Eotaxin-2 and colorectal cancer: a potential target for immune therapy. Clin. Cancer Res., 2007-10-01;13(19):5719-28. 2007-10-01 [PMID: 17908961] (ELISA Development, Human)	ELISA Development	Human
Todd J, Freese B, Lu A, Held D, Morey J, Livingston R, Goix P Ultrasensitive flow-based immunoassays using single-molecule counting. Clin. Chem., 2007-09-21;53(11):1990-5. 2007-09-21 [PMID: 17890441] (ELISA Development, Human)	ELISA Development	Human
Fitzgerald DC, Meade KG, McEvoy AN, Lillis L, Murphy EP, Machugh DE, Baird AW Tumour necrosis factor-alpha (TNF-alpha) increases nuclear factor kappaB (NFkappaB) activity in and interleukin-8 (IL-8) release from bovine mammary epithelial cells. Vet. Immunol. Immunopathol., 2007-01-09;116(1):59-68. 2007-01-09 [PMID: 17276517] (ELISA Development, Bovine)	ELISA Development	Bovine
Abe Y, Fornage M, Yang CY, Bui-Thanh NA, Wise V, Chen HH, Rangaraj G, Ballantyne CM L5, the most electronegative subfraction of plasma LDL, induces endothelial vascular cell adhesion molecule 1 and CXC chemokines, which mediate mononuclear leukocyte adhesion. Atherosclerosis, 2006-10-04;192(1):56-66. 2006-10-04 [PMID: 17022986] (Neutralization, Human)	Neutralization	Human
Hajjar AM, Harvey MD, Shaffer SA, Goodlett DR, Sjostedt A, Edebro H, Forsman M, Bystrom M, Pelletier M, Wilson CB, Miller SI, Skerrett SJ, Ernst RK Lack of in vitro and in vivo recognition of Francisella tularensis subspecies lipopolysaccharide by Toll-like receptors. Infect. Immun., 2006-09-18;74(12):6730-8. 2006-09-18 [PMID: 16982824] (ELISA Development, Human)	ELISA Development	Human
Hatfield K, Ryningen A, Corbascio M, Bruserud O Microvascular endothelial cells increase proliferation and inhibit apoptosis of native human acute myelogenous leukemia blasts. Int. J. Cancer, 2006-11-15;119(10):2313-21. 2006-11-15 [PMID: 16921487] (Neutralization, Human)	Neutralization	Human
Rofstad EK, Mathiesen B, Kindem K, Galappathi K Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice. Cancer Res., 2006-07-01;66(13):6699-707. 2006-07-01 [PMID: 16818644] (Neutralization, Complex Species Category)	Neutralization	Complex Species Category
Gounni Abdelilah S, Wellemans V, Agouli M, Guenounou M, Hamid Q, Beck LA, Lamkhioued B Increased expression of Th2-associated chemokines in bullous pemphigoid disease. Role of eosinophils in the production and release of these chemokines. Clin. Immunol., 2006-06-16;120(2):220-31. 2006-06-16 [PMID: 16782408] (ELISA Development, Neutralization, Human)	ELISA Development, Neutralization	Human
Popa ER, Harmsen MC, Tio RA, van der Strate BW, Brouwer LA, Schipper M, Koerts J, De Jongste MJ, Hazenberg A, Hendriks M, van Luyn MJ Circulating CD34+ progenitor cells modulate host angiogenesis and inflammation in vivo. J. Mol. Cell. Cardiol., 2006-06-14;41(1):86-96. 2006-06-14 [PMID: 16780869] (ICC, Human)	ICC	Human
Bersinger NA, von Roten S, Wunder DM, Raio L, Dreher E, Mueller MD PAPP-A and osteoprotegerin, together with interleukin-8 and RANTES, are elevated in the peritoneal fluid of women with endometriosis. Am. J. Obstet. Gynecol., 2006-04-25;195(1):103-8. 2006-04-25 [PMID: 16635455] (ELISA Development, Human)	ELISA Development	Human
Wunder DM, Mueller MD, Birkhauser MH, Bersinger NA Increased ENA-78 in the follicular fluid of patients with endometriosis. Acta Obstet Gynecol Scand, 2006-01-01;85(3):336-42. 2006-01-01 [PMID: 16553183] (ELISA Development, Human)	ELISA Development	Human
Ramachandran R, Morice AH, Compton SJ Proteinase-activated receptor2 agonists upregulate granulocyte colony-stimulating factor, IL-8, and VCAM-1 expression in human bronchial fibroblasts. Am. J. Respir. Cell Mol. Biol., 2006-02-23;35(1):133-41. 2006-02-23 [PMID: 16498082] (ELISA Development, Human)	ELISA Development	Human
Edwards MR, Johnson MW, Johnston SL Combination therapy: Synergistic suppression of virus-induced chemokines in airway epithelial cells. Am. J. Respir. Cell Mol. Biol., 2006-01-19;34(5):616-24. 2006-01-19 [PMID: 16424382] (ELISA Development, Human)	ELISA Development	Human
Numasaki M, Watanabe M, Suzuki T, Takahashi H, Nakamura A, McAllister F, Hishinuma T, Goto J, Lotze MT, Kolls JK, Sasaki H IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis. J. Immunol., 2005-11-01;175(9):6177-89. 2005-11-01 [PMID: 16237115] (Neutralization, Human)	Neutralization	Human
Ren Y, Lin CL, Li Z, Chen XY, Huang X, Lui V, Nicholls J, Lan HY, Tam PK Up-regulation of macrophage migration inhibitory factor in infants with acute neonatal necrotizing enterocolitis. Histopathology, 2005-06-01;46(6):659-67. 2005-06-01 [PMID: 15910597] (ICC, Human)	ICC	Human
Holst RM, Mattsby-Baltzer I, Wennerholm UB, Hagberg H, Jacobsson B Interleukin-6 and interleukin-8 in cervical fluid in a population of Swedish women in preterm labor: relationship to microbial invasion of the amniotic fluid, intra-amniotic inflammation, and preterm delivery. Acta Obstet Gynecol Scand, 2005-06-01;84(6):551-7. 2005-06-01 [PMID: 15901266] (ELISA Development, Human)	ELISA Development	Human
Malgorzata Goczalik I, Raap M, Weick M, Milenkovic I, Heidmann J, Enzmann V, Wiedemann P, Reichenbach A, Francke M The activation of IL-8 receptors in cultured guinea pig Muller glial cells is modified by signals from retinal pigment epithelium. J. Neuroimmunol., 2005-04-01;161(1):49-60. 2005-04-01 [PMID: 15748943] (ICC, Guinea Pig)	ICC	Guinea Pig
Penninckx F, Ectors N GCP-2/CXCL6 synergizes with other endothelial cell-derived chemokines in neutrophil mobilization and is associated with angiogenesis in gastrointestinal tumors. Exp. Cell Res., 2005-02-15;303(2):331-42. 2005-02-15 [PMID: 15652347] (ELISA Development, Human)	ELISA Development	Human
Phillips TM Rapid analysis of inflammatory cytokines in cerebrospinal fluid using chip-based immunoaffinity electrophoresis. Electrophoresis, 2004-06-01;25(10):1652-9. 2004-06-01 [PMID: 15188254] (Affinity Chromatography, Human)	Affinity Chromatography	Human
Bengtsson AK, Ryan EJ, Giordano D, Magaletti DM, Clark EA 17beta-estradiol (E2) modulates cytokine and chemokine expression in human monocyte-derived dendritic cells. Blood, 2004-05-13;104(5):1404-10. 2004-05-13 [PMID: 15142882] (ELISA Development, Human)	ELISA Development	Human
Copeland S, Siddiqui J, Remick D Direct comparison of traditional ELISAs and membrane protein arrays for detection and quantification of human cytokines. J. Immunol. Methods, 2004-01-01;284(1):99-106. 2004-01-01 [PMID: 14736420] (Array Development, Human)	Array Development	Human
Maheshwari A, Christensen RD, Calhoun DA ELR+ CXC chemokines in human milk. Cytokine, 2003-11-07;24(3):91-102. 2003-11-07 [PMID: 14581003] (IHC-P, Human)	IHC-P	Human
Park JS, 107290, Kim YS, Jee YK, Myong NH, Lee KY Interleukin-8 production in tuberculous pleurisy: role of mesothelial cells stimulated by cytokine network involving tumour necrosis factor-alpha and interleukin-1 beta. Active immunotherapy against pathogenic Cis pT231-tau suppresses neurodegeneration in traumatic brain injury mouse models, 2003-05-01;57(5):463-9. 2003-05-01 [PMID: 12753503] (IHC, Human)	IHC	Human
Hurst SM, McLoughlin RM, Monslow J, Owens S, Morgan L, Fuller GM, Topley N, Jones SA Secretion of oncostatin M by infiltrating neutrophils: regulation of IL-6 and chemokine expression in human mesothelial cells. J. Immunol., 2002-11-01;169(9):5244-51. 2002-11-01 [PMID: 12391243] (ELISA Development, Human)	ELISA Development	Human
Huber TB, Reinhardt HC, Exner M, Burger JA, Kerjaschki D, Saleem MA, Pavenstadt H Expression of functional CCR and CXCR chemokine receptors in podocytes. J. Immunol., 2002-06-15;168(12):6244-52. 2002-06-15 [PMID: 12055238] (IHC-Fr, Human)	IHC-Fr	Human
Humes HD, Fissell WH, Weitzel WF, Buffington DA, Westover AJ, MacKay SM, Gutierrez JM Metabolic replacement of kidney function in uremic animals with a bioartificial kidney containing human cells. Am. J. Kidney Dis., 2002-05-01;39(5):1078-87. 2002-05-01 [PMID: 11979353] (ELISA Development, Human)	ELISA Development	Human
Hirst SJ, Hallsworth MP, Peng Q Selective induction of eotaxin release by interleukin-13 or interleukin-4 in human airway smooth muscle cells is synergistic with interleukin-1beta and is mediated by the interleukin-4 receptor alpha-chain. Am. J. Respir. Crit. Care Med., 2002-04-15;165(8):1161-71. 2002-04-15 [PMID: 11956062] (ELISA Development, Human)	ELISA Development	Human
Hurst SM, Wilkinson TS, McLoughlin RM, Jones S, Horiuchi S, Yamamoto N, Rose-John S, Fuller GM, Topley N, Jones SA Il-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation. Immunity, 2001-06-01;14(6):705-14. 2001-06-01 [PMID: 11420041] (ELISA Development, Human)	ELISA Development	Human
Bottcher MF, Jenmalm MC, Bjorksten B, Garofalo RP Chemoattractant factors in breast milk from allergic and nonallergic mothers. Pediatr. Res., 2000-05-01;47(5):592-7. 2000-05-01 [PMID: 10813582] (ELISA Development, Human)	ELISA Development	Human
Show All 183 Publications. Collapse Publications.

Images	Ratings	Applications	Species	Date	Details
Enlarge	4 reviewed by: Verified Customer	IHC-P	Human	08/30/2018	View Summary Application Immunohistochemistry-Paraffin Sample Tested Human lymph node (melanoma) Species Human Lot ASJ3517041 Comments Comments Human FFPE metastatic melanoma lymph node sections were stained with anti-human IL-8 monoclonal antibody (MAB208) at 5 µg/ml followed by secondary goat anti-mouse biotinylated antibody and Streptavidin AP conjugate. Detection via an Alkaline Phosphatase/Red staining System. Blocking: 5 % goat Serum in TBS-T Antigen Retrieval: Citrat buffer Primary antibody incubation: over night at 4 °C

Array MAB208

• CXCL8/IL-8 Antibodies
• CXCL8/IL-8 Antibody Pair
• CXCL8/IL-8 ELISA Kits
• CXCL8/IL-8 Kits
• CXCL8/IL-8 Lysate
• CXCL8/IL-8 Proteins
• CXCL8/IL-8 Proteins and Enzymes
• CXCL8/IL-8 ELISAs