Histone Deacetylase 4/HDAC4 Antibody Blocking Peptide Summary
Specificity |
This peptide is specific for NBP2-22151 only. |
Protein/Peptide Type |
Antibody Blocking Peptide |
Gene |
HDAC4 |
Applications/Dilutions
Dilutions |
|
Application Notes |
This peptide is useful as a blocking peptide for NBP2-22151. For further blocking peptide related protocol, click here. |
Packaging, Storage & Formulations
Storage |
Store at -80C. Avoid freeze-thaw cycles. |
Buffer |
Peptide dissolved in dH20. Contains no BSA. |
Preservative |
No Preservative |
Concentration |
1 mg/ml |
Alternate Names for Histone Deacetylase 4/HDAC4 Antibody Blocking Peptide
Background
Chromatin is a highly specialized structure composed of tightly compacted chromosomal DNA. Gene expression within the nucleus is controlled, in part, by a host of protein complexes which continuously pack and unpack the chromosomal DNA. One of the known mechanisms of this packing and unpacking process involves the acetylation and deacetylation of the histone proteins comprising the nucleosomal core. Acetylated histone proteins confer accessibility of the DNA template to the transcriptional machinery for expression. Histone deacetylases (HDACs) are chromatin remodeling factors that deacetylate histone proteins and thus, may act as transcriptional repressors. HDACs are classified by their sequence homology to the yeast HDACs and there are currently 2 classes. Class I proteins are related to Rpd3 and members of class II resemble Hda1p.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are
guaranteed for 3 months from date of receipt.
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