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HDAC7 [p Ser318] Antibody - BSA Free

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Western Blot: HDAC7 [p Ser318] Antibody [NBP2-03978] - Analysis of phospho HDAC7 in (A) recombinant fusion protein containing a phosphorylated serine at position 318 and (B) fusion protein containinug an ...read more

Product Details

Summary
Reactivity Hu, Bv, Ca, Eq, Pm, Ze, Mu, Rt, ChSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1.0 mg/ml

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HDAC7 [p Ser318] Antibody - BSA Free Summary

Immunogen
A synthetic peptide containing phospho-serine 318 of human HDAC7 was used as the immunogen.
Modification
p Ser318
Predicted Species
Mouse (90%), Rat (90%), Chicken (90%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
HDAC7
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 0.1 - 1 ug/mL
Publications
Read Publication using NBP2-03978.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for HDAC7 [p Ser318] Antibody - BSA Free

  • DKFZP586J0917
  • EC 3.5.1.98
  • HD7
  • HD7a
  • HDAC7
  • HDAC7A
  • HDAC7AFLJ99588
  • histone deacetylase 7
  • Histone deacetylase 7ADKFZp586J0917

Background

Histone deacetylase 7 is a thymus-specific, intracellular transcription factor belonging to the class IIa histone deacetylase family. Reports suggest that dephosphorylation and nuclear localization of HDAC-7 is promoted by Myosin phosphatase, thus regulating the repression of Nur77 and inhibition of apoptosis in CD4+CD8+ double-positive thymocytes. HDAC-7 plays a specific role in maintaining vascular integrity by repressing the expression of matrix metalloproteinase (MMP) 10. It promotes repression mediated by transcriptional corepressor NCOR2 and is an efficient corepressor of the androgen receptor (AR). It is also responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for HDAC7 Antibody (NBP2-03978)(1)

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Bioinformatics

Gene Symbol HDAC7
Uniprot