![Product Image: GRP78/HSPA5 Antibody [DyLight 488] [NBP1-06274G] - Vial of DyLight 488 conjugated antibody. DyLight 488 is optimally excited at 493 nm by the Blue laser (488 nm) and has an emission maximum of 518 nm.](http://images.novusbio.com/fullsize/GRP78-HSPA5-Antibody-[DyLight-488]-Product-Image-NBP1-06274G-img0001.jpg "Product Image: GRP78/HSPA5 Antibody [DyLight 488] [NBP1-06274G] - Vial of DyLight 488 conjugated antibody. DyLight 488 is optimally excited at 493 nm by the Blue laser (488 nm) and has an emission maximum of 518 nm.")
| Reactivity | Hu, Mu, Rt, Ce, Ch, Dr, Sh, Ze, Bv, PmSpecies Glossary |
| Applications | WB, Simple Western, Flow, ICC/IF, IHC, IHC |
| Clonality | Polyclonal |
| Host | Rabbit |
| Conjugate | DyLight 488 |
| Immunogen | Synthetic peptide made to an internal portion of human GRP78 (within residues 250-300). [Swiss-Prot# P11021] |
| Localization | Endoplasmic reticulum lumen. Melanosome. Note: Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
| Marker | ER Stress Marker |
| Predicted Species | Primate (100%), Bovine (100%). Backed by our 100% Guarantee. |
| Isotype | IgG |
| Clonality | Polyclonal |
| Host | Rabbit |
| Gene | HSPA5 |
| Purity | Immunogen affinity purified |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
| Dilutions |
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| Application Notes | Optimal dilution of this antibody should be experimentally determined. |
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| Publications |
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| Storage | Store at 4C in the dark. |
| Buffer | 50mM Sodium Borate |
| Preservative | 0.05% Sodium Azide |
| Purity | Immunogen affinity purified |
![Immunohistochemistry-Paraffin IRE1 alpha [p Ser724] Antibody - BSA Free](https://images.novusbio.com/images/IRE1-alpha-[p-Ser724]-Antibody-Immunohistochemistry-Paraffin-NB100-2323-img0025.jpg)
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![GRP78/HSPA5 Antibody [DyLight 488]](/sites/all/modules/enterprise-tech/et_datasheets/images/novus_guarantee.png "GRP78/HSPA5 Antibody [DyLight 488]")
Secondary Antibodies |
Isotype Controls |
Research Areas for GRP78/HSPA5 Antibody (NBP1-06274G)Find related products by research area.
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GRP78 - molecular chaperone and negative regulator of the unfolded protein response The 78 kDa glucose-regulated protein (GRP78) is the eukaryotic orthologue to the prokaryotic heat shock 70 kDa protein 5 (HSPA5). GRP78 is also sometimes referred to as BiP. GRP78 is a member of the HSP70 family and plays dynamic roles in protein ... Read full blog post. |
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| Gene Symbol | HSPA5 |
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![Western Blot: Goat anti-Rabbit IgG (H+L) Secondary Antibody [HRP] [NB7160] - Western blot showing vemurafenib treatment in BRAFV600E CRC cells inhibits fission mediator DRP1 with no significant effect on fusion proteins (Mfn1 & 2) using MFN-1 antibody (NBP1-51841) and corresponding secondary antibody, goat anti-rabbit IgG-HRP (NB7160). Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/33738242).](https://images.novusbio.com/images/Goat-anti-Rabbit-IgG-H+L-Secondary-Antibody-HRP-Western-Blot-NB7160-img0001.jpg "Western Blot: Goat anti-Rabbit IgG (H+L) Secondary Antibody [HRP] [NB7160] - Western blot showing vemurafenib treatment in BRAFV600E CRC cells inhibits fission mediator DRP1 with no significant effect on fusion proteins (Mfn1 & 2) using MFN-1 antibody (NBP1-51841) and corresponding secondary antibody, goat anti-rabbit IgG-HRP (NB7160). Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/33738242).")
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