ATF4 Antibody

ATF4 is a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain (referenced from Entrez gene).

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 1 application: WB.

Showing Publications 1 - 7 of 7.

Publications using NB100-852	Applications	Species
VAsquez-Trincado C, Patel M, Sivaramakrishnan A et al. Adaptation of the heart to Frataxin depletion: Evidence that integrated stress response can predominate over mTORC1 activation Human molecular genetics 2021-09-22 [PMID: 34550363]
Albayrak D, Doganlar O, Erdogan S et al. Naringin Combined with NF-kappa B Inhibition and Endoplasmic Reticulum Stress Induces Apoptotic Cell Death via Oxidative Stress and the PERK/eIF2 alpha/ATF4/CHOP Axis in HT29 Colon Cancer Cells Biochem. Genet. 2020-09-26 [PMID: 32979141] (Human)		Human
Besio R, Garibaldi N, Leoni L et al. Cellular stress due to impairment of collagen prolyl hydroxylation complex is rescued by the chaperone 4-phenylbutyrate Dis Model Mech. 2019-06-20 [PMID: 31171565] (WB, Human)	WB	Human
Zhang W, Zhong W, Sun Q et al. Adipose-specific lipin1 overexpression in mice protects against alcohol-induced liver injury. Sci Rep 2018-01-11 [PMID: 29323242] (WB, Mouse)	WB	Mouse
Khalyfa A, Qiao Z, Gileles-Hillel A et al. Activation of the Integrated Stress Response and Metabolic Dysfunction in a Murine Model of Sleep Apnea. Am. J. Respir. Cell Mol. Biol. 2017-10-01 [PMID: 28594573] (WB, Mouse)	WB	Mouse
Kim DI, Park MJ, Choi JH et al. Hyperglycemia-induced GLP-1R downregulation causes RPE cell apoptosis. Int J Biochem Cell Biol. [PMID: 25483438] (WB, Human)	WB	Human
Tsujimoto A, Nyunoya H, Morita T et al. Isolation of cDNAs for DNA-binding proteins which specifically bind to a tax-responsive enhancer element in the long terminal repeat of human T-cell leukemia virus type I. J Virol 1991-03-01 [PMID: 1847461]

Images	Ratings	Applications	Species	Date	Details
Enlarge	5 reviewed by: Verified Customer	WB	Mouse	02/06/2018	View Summary Application Western Blot Sample Tested Mouse whole liver Species Mouse Lot c2

Array NB100-852

• ATF4 Antibodies
• ATF4 Antibody Pair
• ATF4 ELISA Kit
• ATF4 Protein