Immunohistochemistry-Paraffin: Flt-3/Flk-2/CD135 Antibody (12B6) [NB110-94155] - Flt-3 antibody staining in mouse lung cancer tissue. IHC-P image submitted by a verified customer review.
Immunohistochemistry: Flt3/CD135 Antibody (12B6) [NB110-94155] - Paraffin kidney and lung sections from LPS treated mice were subjected to IHC using anti Flt3/CD135 Antibody (12B6) RM0021-12B6
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein G purified
Reconstitution Instructions
Reconstitute with sterilized PBS to a final concentration of 0.2 mg/ml.
Alternate Names for Flt-3/Flk-2/CD135 Antibody (12B6) - Azide and BSA Free
CD135 antigen
CD135
EC 2.7.10
fetal liver kinase 2
FL cytokine receptor
FLK2
Flk-2
FLT3 receptor tyrosine kinase
Flt3
Flt-3
Fms-like tyrosine kinase 3
fms-related tyrosine kinase 3
growth factor receptor tyrosine kinase type III
Stem cell tyrosine kinase 1
STK-1
STK1EC 2.7.10.1
Tyrosine-protein kinase receptor FLT3
Background
Stem cell tyrosine kinase (STK-1) has been cloned from a CD34+ hematopoietic stem cell enriched library and identified as the human homolog of a previously identified gene of mouse origin designated either Flk-2 or Flt-3. The STK-1 cDNA encodes a protein of 993 amino acids with 85% identity to Flt-3/Flk-2. STK-1 is a member of the type III receptor tyrosine kinase family that includes Kit (steel factor receptor), Fms and PDGF. STK-1 expression in blood and marrow is restricted to CD34+ cells, a population greatly enriched for hematopoietic stem/progenitor cells. STK-1 antiserum recognizes two polypeptides in these cells. The mouse homolog of STK-1, designated Flt-3/ Flk-2, is expressed at high levels in hematopoietic cells and also in neural, gonadal, hepatic and placental tissues. It has been suggested that STK-1 and its murine homolog Flt-3/ Flk-2 may function as growth factor receptors on hematopoietic stem and/or progenitor cells.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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