Home » Flt-3/Flk-2/CD135 » Flt-3/Flk-2/CD135 Antibodies » Flt-3/Flk-2/CD135 Antibody (12B6) [Janelia Fluor® 525]
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Flt-3/Flk-2/CD135 Antibody (12B6) [Janelia Fluor® 525]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, IHC
Clone
12B6
Clonality
Monoclonal
Host
Rat
Conjugate
Janelia Fluor 525

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB110-94155AF350
Alexa Fluor 405
NB110-94155AF405
Alexa Fluor 488
NB110-94155AF488
Alexa Fluor 532
NB110-94155AF532
Alexa Fluor 594
NB110-94155AF594
Alexa Fluor 647
NB110-94155AF647
Alexa Fluor 700
NB110-94155AF700
Alexa Fluor 750
NB110-94155AF750
Allophycocyanin
NB110-94155APC
Biotin
NB110-94155B
CoraFluor 1
NB110-94155CL1
DyLight 350
NB110-94155UV
DyLight 405
NB110-94155V
DyLight 488
NB110-94155G
DyLight 550
NB110-94155R
DyLight 594
NB110-94155DL594
DyLight 650
NB110-94155C
DyLight 680
NB110-94155FR
DyLight 755
NB110-94155IR
FITC
NB110-94155F
HRP
NB110-94155H
Janelia Fluor 549
NB110-94155JF549
Janelia Fluor 585
NB110-94155JF585
Janelia Fluor 635
NB110-94155JF635
Janelia Fluor 646
NB110-94155JF646
Janelia Fluor 669
NB110-94155JF669
PE
NB110-94155PE
PerCP
NB110-94155PCP
Unconjugated
NB110-94155
mFluor Violet 450 SE
NB110-94155MFV450
mFluor Violet 500 SE
NB110-94155MFV500
mFluor Violet 610 SE
NB110-94155MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB110-94155
Azide and BSA Free
NB110-94155
Azide and BSA Free
NB110-94155-0.025mg
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Flt-3/Flk-2/CD135 Antibody (12B6) [Janelia Fluor® 525] Summary

Immunogen
Mouse Flt-3/Flk-2/CD135 (extracellular domain)
Isotype
IgG2
Clonality
Monoclonal
Host
Rat
Gene
FLT3
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Flt-3/Flk-2/CD135 Antibody (12B6) [Janelia Fluor® 525]

  • CD135 antigen
  • CD135
  • EC 2.7.10
  • fetal liver kinase 2
  • FL cytokine receptor
  • FLK2
  • Flk-2
  • FLT3 receptor tyrosine kinase
  • Flt3
  • Flt-3
  • Fms-like tyrosine kinase 3
  • fms-related tyrosine kinase 3
  • growth factor receptor tyrosine kinase type III
  • Stem cell tyrosine kinase 1
  • STK-1
  • STK1EC 2.7.10.1
  • Tyrosine-protein kinase receptor FLT3

Background

Stem cell tyrosine kinase (STK-1) has been cloned from a CD34+ hematopoietic stem cell enriched library and identified as the human homolog of a previously identified gene of mouse origin designated either Flk-2 or Flt-3. The STK-1 cDNA encodes a protein of 993 amino acids with 85% identity to Flt-3/Flk-2. STK-1 is a member of the type III receptor tyrosine kinase family that includes Kit (steel factor receptor), Fms and PDGF. STK-1 expression in blood and marrow is restricted to CD34+ cells, a population greatly enriched for hematopoietic stem/progenitor cells. STK-1 antiserum recognizes two polypeptides in these cells. The mouse homolog of STK-1, designated Flt-3/ Flk-2, is expressed at high levels in hematopoietic cells and also in neural, gonadal, hepatic and placental tissues. It has been suggested that STK-1 and its murine homolog Flt-3/ Flk-2 may function as growth factor receptors on hematopoietic stem and/or progenitor cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol FLT3