Home » Flt-3/Flk-2/CD135 » Flt-3/Flk-2/CD135 Antibodies » Flt-3/Flk-2/CD135 Antibody (113308) [Alexa Fluor® 594]
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Flt-3/Flk-2/CD135 Antibody (113308) [Alexa Fluor® 594]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow
Clone
113308
Clonality
Monoclonal
Host
Rat
Conjugate
Alexa Fluor 594
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB7681U-100UG
Alexa Fluor 405
FAB7681V-100UG
Alexa Fluor 488
FAB7681G-100UG
Alexa Fluor 532
FAB7681X
Alexa Fluor 647
FAB7681R-100UG
Alexa Fluor 700
FAB7681N-100UG
Alexa Fluor 750
FAB7681S-100UG
Allophycocyanin/Cy7
FAB7681APCCY7
Biotin
BAM7681
CoraFluor 1
FAB7681CL1
DyLight 350
FAB7681D
DyLight 405
FAB7681E
DyLight 488
FAB7681K
DyLight 550
FAB7681L
DyLight 594
FAB7681M
DyLight 650
FAB7681W
DyLight 680
FAB7681Y
DyLight 755
FAB7681Z
FITC
FAB7681F
HRP
FAB7681H
Janelia Fluor 525
FAB7681JF525
Janelia Fluor 549
FAB7681I
Janelia Fluor 585
FAB7681JF585
Janelia Fluor 635
FAB7681JF635
Janelia Fluor 646
FAB7681J
Janelia Fluor 669
FAB7681JF669
PE/Atto594
FAB7681PEATT594
PE/Cy5.5
FAB7681PECY55
PE/Cy7
FAB7681PECY7
PerCP
FAB7681C
Unconjugated
MAB7681
mFluor Violet 450 SE
FAB7681MFV450
mFluor Violet 500 SE
FAB7681MFV500
mFluor Violet 610 SE
FAB7681MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB7681
Carrier Free
MAB7681
Carrier Free
MAB7681-SP
Carrier Free
FAB7681V-100UG
Carrier Free
FAB7681U-100UG
Carrier Free
FAB7681S-100UG
Carrier Free
FAB7681R-100UG
Carrier Free
FAB7681N-100UG
Carrier Free
FAB7681G-100UG
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Flt-3/Flk-2/CD135 Antibody (113308) [Alexa Fluor® 594] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Flt‑3/Flk‑2
Asn28-Ser544 (predicted)
Accession # Q00342
Specificity
Detects mouse Flt‑3/Flk‑2 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human Flt-3 is observed.
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
FLT3
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • Flow Cytometry 0.25-1 ug/10^6 cells
Application Notes
Flow Cytometry: Please use 0.25-1 ug of conjugated antibody per 10e6 cells.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Buffer
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Preservative
0.09% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.

Notes


This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Flt-3/Flk-2/CD135 Antibody (113308) [Alexa Fluor® 594]

  • CD135 antigen
  • CD135
  • EC 2.7.10
  • fetal liver kinase 2
  • FL cytokine receptor
  • FLK2
  • Flk-2
  • FLT3 receptor tyrosine kinase
  • Flt3
  • Flt-3
  • Fms-like tyrosine kinase 3
  • fms-related tyrosine kinase 3
  • growth factor receptor tyrosine kinase type III
  • Stem cell tyrosine kinase 1
  • STK-1
  • STK1EC 2.7.10.1
  • Tyrosine-protein kinase receptor FLT3

Background

The Flt-3 (fms-like tyrosine kinase) receptor, also named Flk-2 (fetal liver kinase) and Stk-1 (stem cell tyrosine kinase) and designated CD135, is a member of the class III subfamily of receptor tyrosine kinases. This familay includes KIT, the receptor for SCF, and C-FMS, the receptor for M-CSF. The extracellular region of these receptors contains five immunoglobulin-like domains and the intracellular region contains a split kinase domain. Mouse Flt-3 cDNA encodes a 992 amino acid (aa) residue type I membrane protein with a 27 aa residue signal peptide, a 517 aa extracellular domain with 10 potential N-linked glycosylation sites, a 20 aa residue transmembrane domain and a 428 aa residue cytoplasmic domain. Mouse Flt-3 shares 85% amino acid sequence identity with human Flt-3. Flt-3 expression has been detected in various tissues, including placenta, gonads, and tissues of nervous and hematopoietic origin. Among hematopoietic cells, the expression of Flt-3 was found to be restricted to the highly enriched stem/progenitor cell populations. The ligand for Flt-3 (FL) has been identified to be a transmembrane protein with structural homology to M-CSF and SCF. Recombinant soluble Flt-3 Fc chimeric protein has been shown to bind FL with high affinity and is a potent FL antagonist.

  1. Rosnet, O. et al. (1996) Acta. Haemato. 95:218.
  2. Drexler, H.G. (1996) Leukemia 10:588.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol FLT3
Uniprot