Home » Flt-3/Flk-2/CD135 » Flt-3/Flk-2/CD135 Antibodies » Flt-3/Flk-2/CD135 Antibody (113308) [DyLight 650]
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Flt-3/Flk-2/CD135 Antibody (113308) [DyLight 650]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow, CyTOF-ready, ICC/IF
Clone
113308
Clonality
Monoclonal
Host
Rat
Conjugate
DyLight 650

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB7681U-100UG
Alexa Fluor 405
FAB7681V-100UG
Alexa Fluor 488
FAB7681G-100UG
Alexa Fluor 532
FAB7681X
Alexa Fluor 594
FAB7681T-100UG
Alexa Fluor 647
FAB7681R-100UG
Alexa Fluor 700
FAB7681N-100UG
Alexa Fluor 750
FAB7681S-100UG
Allophycocyanin/Cy7
FAB7681APCCY7
Biotin
BAM7681
CoraFluor 1
FAB7681CL1
DyLight 350
FAB7681D
DyLight 405
FAB7681E
DyLight 488
FAB7681K
DyLight 550
FAB7681L
DyLight 594
FAB7681M
DyLight 680
FAB7681Y
DyLight 755
FAB7681Z
FITC
FAB7681F
HRP
FAB7681H
Janelia Fluor 525
FAB7681JF525
Janelia Fluor 549
FAB7681I
Janelia Fluor 585
FAB7681JF585
Janelia Fluor 635
FAB7681JF635
Janelia Fluor 646
FAB7681J
Janelia Fluor 669
FAB7681JF669
PE/Atto594
FAB7681PEATT594
PE/Cy5.5
FAB7681PECY55
PE/Cy7
FAB7681PECY7
PerCP
FAB7681C
Unconjugated
MAB7681
mFluor Violet 450 SE
FAB7681MFV450
mFluor Violet 500 SE
FAB7681MFV500
mFluor Violet 610 SE
FAB7681MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB7681
Carrier Free
MAB7681
Carrier Free
MAB7681-SP
Carrier Free
FAB7681V-100UG
Carrier Free
FAB7681U-100UG
Carrier Free
FAB7681T-100UG
Carrier Free
FAB7681S-100UG
Carrier Free
FAB7681R-100UG
Carrier Free
FAB7681N-100UG
Carrier Free
FAB7681G-100UG
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Flt-3/Flk-2/CD135 Antibody (113308) [DyLight 650] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Flt‑3/Flk‑2
Asn28-Ser544 (predicted)
Accession # Q00342
Specificity
Detects mouse Flt‑3/Flk‑2 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human Flt-3 is observed.
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
FLT3
Purity
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Immunocytochemistry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Flt-3/Flk-2/CD135 Antibody (113308) [DyLight 650]

  • CD135 antigen
  • CD135
  • EC 2.7.10
  • fetal liver kinase 2
  • FL cytokine receptor
  • FLK2
  • Flk-2
  • FLT3 receptor tyrosine kinase
  • Flt3
  • Flt-3
  • Fms-like tyrosine kinase 3
  • fms-related tyrosine kinase 3
  • growth factor receptor tyrosine kinase type III
  • Stem cell tyrosine kinase 1
  • STK-1
  • STK1EC 2.7.10.1
  • Tyrosine-protein kinase receptor FLT3

Background

Stem cell tyrosine kinase (STK-1) has been cloned from a CD34+ hematopoietic stem cell enriched library and identified as the human homolog of a previously identified gene of mouse origin designated either Flk-2 or Flt-3. The STK-1 cDNA encodes a protein of 993 amino acids with 85% identity to Flt-3/Flk-2. STK-1 is a member of the type III receptor tyrosine kinase family that includes Kit (steel factor receptor), Fms and PDGF. STK-1 expression in blood and marrow is restricted to CD34+ cells, a population greatly enriched for hematopoietic stem/progenitor cells. STK-1 antiserum recognizes two polypeptides in these cells. The mouse homolog of STK-1, designated Flt-3/ Flk-2, is expressed at high levels in hematopoietic cells and also in neural, gonadal, hepatic and placental tissues. It has been suggested that STK-1 and its murine homolog Flt-3/ Flk-2 may function as growth factor receptors on hematopoietic stem and/or progenitor cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol FLT3