CCR2 Antibody (3G7) - BSA Free

CCR2, or C-C chemokine receptor type 2, is a receptor for several monocyte chemo attractant proteins (MCP1, MCP3, MCP4) which specifically mediate monocyte chemotaxis. CCR2 transduces such signals by increasing the intracellular level of calcium ions. For example, MCP1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. CCR2 is also an alternative coreceptor with CD4 for HIV1 infection. CCR2 has two isoforms and has been reported to be expressed in a wide variety of tissues, including blood, brain, heart, kidney, liver, lung, ovary, pancreas, spinal cord, spleen and thymus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 4 applications: ICC/IF, IHC, IHC-P, WB.

Showing Publications 1 - 10 of 10.

Publications using NBP2-35334	Applications	Species
Liu Z, Geng Y, Huang Y et al. Bushen Antai Recipe Alleviates Embryo Absorption by Enhancing Immune Tolerance and Angiogenesis at Maternal-Fetal Interface Via Mobilizing Mdscs in Abortion-Prone Mice SSRN 2023-06-24 [PMID: 37952407] (WB, IHC, Mouse)	WB, IHC	Mouse
Liu Z, Song Y, Hu R et al. Bushen Antai recipe ameliorates immune microenvironment and maternal-fetal vascularization in STAT3-deficient abortion-prone mice Journal of ethnopharmacology 2023-07-08 [PMID: 37423519] (WB, Mouse)	WB	Mouse
Li R, Wu X, Peng S et al. CCR2 antagonist represses fibroblast-like synoviocyte-mediated inflammation in patients with rheumatoid arthritis International immunopharmacology 2023-06-28 [PMID: 37390649]
Ma K, Singh G, Wang J et al. Targeting Vascular Endothelial Growth Factor Receptors as a Therapeutic Strategy for Osteoarthritis and Associated Pain International Journal of Biological Sciences 2023-01-03 [PMID: 36632459] (IHC-P, Mouse) Details: Dilution used in IHC-P 1:100	IHC-P	Mouse
Oz HH, Cheng EC, Di Pietro C et al. Recruited monocytes/macrophages drive pulmonary neutrophilic inflammation and irreversible lung tissue remodeling in cystic fibrosis Cell reports 2022-12-13 [PMID: 36516754] (IHC-P, Mouse) Details: Dilution used in IHC-P 1:100	IHC-P	Mouse
Sung PS, Yang SP, Peng YC et al. CLEC5A and TLR2 are critical in SARS-CoV-2-induced NET formation and lung inflammation Journal of biomedical science 2022-07-11 [PMID: 35820906] (IHC-P, Mouse)	IHC-P	Mouse
Han B, Alonso-Valenteen F, Wang Z Et Al. A Chemokine Regulatory Loop Induces Cholesterol Synthesis in Lung-Colonizing Triple-Negative Breast Cancer Cells to Fuel Metastatic Growth Molecular therapy : the journal of the American Society of Gene Therapy 2021-07-15 [PMID: 34274535] (IHC-P, ICC/IF)	IHC-P, ICC/IF
Wenstedt EF, Verberk SG, Kroon J, et al. Salt increases monocyte CCR2 expression and inflammatory responses in humans JCI Insight 2019-11-01 [PMID: 31672939] (IHC-P, Human)	IHC-P	Human
Alghamdi TA, Batchu SN, Hadden MJ, et al. Histone H3 Serine 10 Phosphorylation Facilitates Endothelial Activation in Diabetic Kidney Disease Diabetes 2018 Dec 01 [PMID: 30213824] (WB, Mouse)	WB	Mouse
Zhang Yun, Liu Shaohua, Qu Daiwei et al. Kif4A mediate the accumulation and reeducation of THP-1 derived macrophages via regulation of CCL2-CCR2 expression in crosstalking with OSCC. Sci Rep 2017-01-01 [PMID: 28533507] (WB, Human)	WB	Human

Images	Ratings	Applications	Species	Date	Details
Enlarge	4 reviewed by: Verified Customer	ICC	Other	02/02/2015	View Summary Application Immunocytochemistry Sample Tested rabbit spleen isolated primary cells Species Other Lot A-1

Array NBP2-35334

• CCR2 Antibodies
• CCR2 ELISA Kit
• CCR2 Lysates
• CCR2 Proteins