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CCR2 Antibody (3G7) [DyLight 488]

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Product Details

Summary
Reactivity Hu, Mu, PmSpecies Glossary
Applications WB, ICC/IF, IHC
Clone
3G7
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 488

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-35334AF350
Alexa Fluor 405
NBP2-35334AF405
Alexa Fluor 488
NBP2-35334AF488
Alexa Fluor 532
NBP2-35334AF532
Alexa Fluor 594
NBP2-35334AF594
Alexa Fluor 647
NBP2-35334AF647
Alexa Fluor 700
NBP2-35334AF700
Alexa Fluor 750
NBP2-35334AF750
Biotin
NBP2-35334B
DyLight 350
NBP2-35334UV
DyLight 405
NBP2-35334V
DyLight 550
NBP2-35334R
DyLight 594
NBP2-35334DL594
DyLight 650
NBP2-35334C
DyLight 680
NBP2-35334FR
DyLight 755
NBP2-35334IR
FITC
NBP2-35334F
HRP
NBP2-35334H
Janelia Fluor 549
NBP2-35334JF549
Janelia Fluor 646
NBP2-35334JF646
Unconjugated
NBP2-35334
mFluor Violet 450 SE
NBP2-35334MFV450
mFluor Violet 500 SE
NBP2-35334MFV500
mFluor Violet 610 SE
NBP2-35334MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-35334
BSA Free
NBP2-35334SS
BSA Free
NBP2-35334
Azide and BSA Free
NBP2-80623
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CCR2 Antibody (3G7) [DyLight 488] Summary

Immunogen
A synthetic peptide made to an N-terminal portion of the human CD63 protein (between residues 1-100) [UniProt P41597]
Localization
Cell membrane
Predicted Species
Primate (100%). Backed by our 100% Guarantee.
Isotype
IgG2b Lambda
Clonality
Monoclonal
Host
Mouse
Gene
CCR2
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 30213824).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for CCR2 Antibody (3G7) [DyLight 488]

  • C-C chemokine receptor type 2
  • C-C CKR-2
  • CC-CKR-2
  • CC-CKR-2CKR2B
  • CCR2
  • CCR-2
  • CCR2A
  • CCR2B
  • CD192 antigen
  • CD192
  • chemokine (C-C motif) receptor 2
  • CKR2
  • CKR2A
  • CMKBR2
  • CMKBR2MGC111760
  • FLJ78302
  • MCP-1 receptor
  • MCP-1-R
  • MCP-1-RMGC103828
  • MGC168006
  • Monocyte chemoattractant protein 1 receptor
  • monocyte chemotactic protein 1 receptor

Background

CCR2, or C C chemokine receptor type 2, is a receptor for several monocyte chemo attractant proteins (MCP1, MCP3, MCP4) which specifically mediate monocyte chemotaxis. CCR2 transduces such signals by increasing the intracellular level of calcium ions. For example, MCP1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. CCR2 is also an alternative coreceptor with CD4 for HIV1 infection. CCR2 has two isoforms and has been reported to be expressed in a wide variety of tissues, including blood, brain, heart, kidney, liver, lung, ovary, pancreas, spinal cord, spleen and thymus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for CCR2 Antibody (NBP2-35334G) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CCR2