BMPR-II Antibody - Azide and BSA Free

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Genetic Strategies: Western Blot: BMPR-II Antibody [NBP3-03627] - Analysis of extracts from normal (control) and BMPR2 knockout (KO) HeLa cells, using BMPR-II antibody at 1:1000 dilution. Secondary antibody: HRP ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, KO
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
Azide and BSA Free
Validated by:
     

Genetic Strategies

   

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BMPR-II Antibody - Azide and BSA Free Summary

Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 27-150 of human BMPR-II (NP_001195.2). SQNQERLCAFKDPYQQDLGIGESRISHENGTILCSKGSTCYGLWEKSKGDINLVKQGCWSHIGDPQECHYEECVVTTTPPSIQNGTYRFCCCSTDLCNVNFTENFPPPDTTPLSPPHSFNRDET
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
BMPR2
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Knockout Validated
  • Western Blot 1:500-1:2000

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 50% glycerol
Preservative
0.01% Thimerosal
Purity
Affinity purified

Alternate Names for BMPR-II Antibody - Azide and BSA Free

  • BMP type II receptor
  • BMP type-2 receptor
  • BMPR2
  • BMPR-2
  • BMPR3
  • BMPRII
  • BMPR-II
  • BMPR-IIprimary pulmonary hypertension 1
  • Bone morphogenetic protein receptor type II
  • bone morphogenetic protein receptor type-2
  • bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • BRK-3
  • EC 2.7.11
  • EC 2.7.11.30
  • FLJ41585
  • FLJ76945
  • PPH1BMR2
  • T-ALK
  • type II activin receptor-like kinase
  • type II receptor for bone morphogenetic protein-4

Background

BMPR2 encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including Methotrexate, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov

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Bioinformatics

Gene Symbol BMPR2