Western Blot: ARHGEF11 Antibody [NBP2-24517] - Analysis of human ARHGEF11 in rat brain lysate in the 1) absence and 2) presence of immunizing peptide using NBP2-24517 at 0.1 ug/ml.
Immunohistochemistry-Paraffin: ARHGEF11 Antibody [NBP2-24517] - IHC analysis of human skin using NBP2-24517 at 10 ug/ml.
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
0.2 ml PBS and 0.2% Gelatin
Preservative
0.05% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified
Alternate Names for ARHGEF11 Antibody
DKFZp667F1223
glutamate transporter EAAT4-associated protein 48
GTRAP48
KIAA0380rho guanine nucleotide exchange factor 11
PDZ-RHOGEF
Rho guanine exchange factor (GEF) 11
Rho guanine nucleotide exchange factor (GEF) 11
RhoA-specific guanine nucleotide exchange factor
RhoGEF glutamate transport modulator
Background
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq]
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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