STAT3 [p Tyr705] Antibody

STATs (signal transducers and activators of transcription) were originally discovered as two proteins (STAT1 and STAT2) which were involved in interferon alpha (IFN alpha) and IFN gamma signal transduction. Since then, several additional STAT proteins have been identified (STAT3, 4, 5a, 5b, and 6). STATs undergo tyrosine phosphorylation in response to growth factor or cytokine signaling. This phosphorylation results in dimerization and translocation of STAT proteins to the nucleus. In some cases this process is mediated by JAK Kinases (Janus Kinases 1, 2, and 3). For maximum activation of these proteins, phosphorylation at specific tyrosine and serine residues may be required in STAT1 alpha, 3, 4, and 5.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Images	Ratings	Applications	Species	Date	Details
	4 reviewed by: loubiere cécile	Simple Western	Mouse	05/19/2021	View Summary Application Simple Western Sample Tested Megakaryocytes Species Mouse Lot 7922 Comments Comments experience made on a Jess ***Novus Innovators Program - new species or application used on a primary antibody.

Array NB100-82213

• STAT3 Antibodies
• STAT3 Lysates
• STAT3 Proteins
• STAT3 ELISA