Recombinant Human SOX2 TAT Protein

This lyophilized preparation is stable at 2-8 degrees C, but should be kept at -20 degrees C for long term storage, preferably desiccated. Upon reconstitution, the preparation is most stable at -20 to -80 degrees C, and can be stored for one week at 2-8 degrees C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 degrees C to -80 degrees C. Avoid repeated freeze/thaw cycles.

Sox2, also named SRY (sex determining region Y)-box 2, is belonging to the Sox family and it is encoded by the Sox gene in human. This protein family shares highly conserved DNA binding domains known as HMG (High-mobility group) box domains containing approximately 80 amino acids. Sox2 plays a role in maintenance of embryonic and neural stem cells and holds great promise in research involving induced pluripotency, an emerging and very promising field of regenerative medicine. Mature human Sox2 shares 100 amino acid sequence identity with murine and rat Sox2. Recombinant human Sox2-TAT expressed in E. coli is a 36 kDa protein containing 330 amino-acid residues, including the 317 residues of full-length Sox2 and a 13-residue Cterminal TAT peptide (GGYGRKKRRQRRR).

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Publication using NBP2-35268	Applications	Species
Schaefer, T;Mittal, N;Wang, H;Ataman, M;Candido, S;Lötscher, J;Velychko, S;Tintignac, L;Bock, T;Börsch, A;Ba beta ler, J;Rao, TN;Zmajkovic, J;Roffeis, S;Löliger, J;Jacob, F;Dumlin, A;Schürch, C;Schmidt, A;Skoda, RC;Wymann, MP;Hess, C;Schöler, HR;Zaehres, H;Hurt, E;Zavolan, M;Lengerke, C; Nuclear and cytosolic fractions of SOX2 synergize as transcriptional and translational co-regulators of cell fate Cell reports 2024-10-03 [PMID: 39368083]

Array NBP2-35268

• SOX2 Antibodies
• SOX2 Lysate
• SOX2 Proteins