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Sortilin Antibody (CL6528) - Azide and BSA Free

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IHC, KD
Clone
CL6528
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
Azide and BSA Free

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-76501AF350
Alexa Fluor 405
NBP2-76501AF405
Alexa Fluor 488
NBP2-76501AF488
Alexa Fluor 532
NBP2-76501AF532
Alexa Fluor 594
NBP2-76501AF594
Alexa Fluor 647
NBP2-76501AF647
Alexa Fluor 700
NBP2-76501AF700
Alexa Fluor 750
NBP2-76501AF750
Allophycocyanin
NBP2-76501APC
Biotin
NBP2-76501B
CoraFluor 1
NBP2-76501CL1
DyLight 350
NBP2-76501UV
DyLight 405
NBP2-76501V
DyLight 488
NBP2-76501G
DyLight 550
NBP2-76501R
DyLight 594
NBP2-76501DL594
DyLight 650
NBP2-76501C
DyLight 680
NBP2-76501FR
DyLight 755
NBP2-76501IR
FITC
NBP2-76501F
HRP
NBP2-76501H
Janelia Fluor 525
NBP2-76501JF525
Janelia Fluor 549
NBP2-76501JF549
Janelia Fluor 585
NBP2-76501JF585
Janelia Fluor 635
NBP2-76501JF635
Janelia Fluor 646
NBP2-76501JF646
Janelia Fluor 669
NBP2-76501JF669
PE
NBP2-76501PE
PerCP
NBP2-76501PCP
Unconjugated
NBP2-76501
mFluor Violet 450 SE
NBP2-76501MFV450
mFluor Violet 500 SE
NBP2-76501MFV500
mFluor Violet 610 SE
NBP2-76501MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-76501
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Sortilin Antibody (CL6528) - Azide and BSA Free Summary

Immunogen
This antibody was generated using a recombinant protein sequence of Q99523, with the exact immunogen sequence remaining proprietary.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
SORT1
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry : 1:200 - 1:500
  • Immunohistochemistry-Paraffin : 1:200 - 1:500
  • Knockdown Validated
  • Western Blot : 1 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Lyophilized in 5% Trehalose.
Preservative
0.02% Sodium Azide
Purity
Protein A purified

Alternate Names for Sortilin Antibody (CL6528) - Azide and BSA Free

  • 100 kDa NT receptor
  • Glycoprotein 95
  • Gp95
  • Gp95LDLCQ6
  • Neurotensin receptor 3
  • NT3NTR3
  • Ntr3
  • SORT1
  • sortilin 1
  • Sortilin

Background

Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Also required for protein transport from the Golgi apparatus to the endosomes. Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also acts as a receptor for neurotensin. May promote mineralization of the extracellular matrix during osteogenic differentiation by scavenging extracellular LPL. Probably required in adipocytes for the formation of specialized storage vesicles containing the glucose transporter SLC2A4/GLUT4 (GLUT4 storage vesicles, or GSVs). These vesicles provide a stable pool of SLC2A4 and confer increased responsiveness to insulin. May also mediate transport from the endoplasmic reticulum to the Golgi.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Antibody - BSA Free
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TNF RII/TNFRSF1B
[HRP]
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Sortilin Antibody
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Sortilin Antibody (CL6528) - Azide and BSA Free
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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol SORT1