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SMURF1 Antibody [Janelia Fluor® 585]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 585

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-41297AF350
Alexa Fluor 405
NBP2-41297AF405
Alexa Fluor 488
NBP2-41297AF488
Alexa Fluor 532
NBP2-41297AF532
Alexa Fluor 594
NBP2-41297AF594
Alexa Fluor 647
NBP2-41297AF647
Alexa Fluor 700
NBP2-41297AF700
Alexa Fluor 750
NBP2-41297AF750
Biotin
NBP2-41297B
CoraFluor 1
NBP2-41297CL1
DyLight 350
NBP2-41297UV
DyLight 405
NBP2-41297V
DyLight 488
NBP2-41297G
DyLight 550
NBP2-41297R
DyLight 594
NBP2-41297DL594
DyLight 650
NBP2-41297C
DyLight 680
NBP2-41297FR
DyLight 755
NBP2-41297IR
FITC
NBP2-41297F
HRP
NBP2-41297H
Janelia Fluor 525
NBP2-41297JF525
Janelia Fluor 549
NBP2-41297JF549
Janelia Fluor 635
NBP2-41297JF635
Janelia Fluor 646
NBP2-41297JF646
Janelia Fluor 669
NBP2-41297JF669
PerCP
NBP2-41297PCP
Unconjugated
NBP2-41297
mFluor Violet 450 SE
NBP2-41297MFV450
mFluor Violet 500 SE
NBP2-41297MFV500
mFluor Violet 610 SE
NBP2-41297MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-41297
BSA Free
NBP2-41297
BSA Free
NBP2-41297-0.025mg
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SMURF1 Antibody [Janelia Fluor® 585] Summary

Immunogen
Antibody was raised against a 16 amino acid peptide near the amino terminus of human SMURF1. The immunogen is located within amino acids 180 - 230 of SMURF1. Amino Acid Squence: RFVESPSQDQRLQAQ
Specificity
At least three isoforms of SMURF1 are known to exist this antibody will recognize all three isoforms. SMURF1 is predicted to not cross-react with SMURF2.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SMURF1
Purity
Peptide affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Peptide affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for SMURF1 Antibody [Janelia Fluor® 585]

  • E3 ubiquitin ligase SMURF1
  • EC 6.3.2
  • EC 6.3.2.-
  • hSMURF1
  • KIAA1625
  • KIAA1625E3 ubiquitin-protein ligase SMURF1
  • SMAD specific E3 ubiquitin protein ligase 1
  • SMAD ubiquitination regulatory factor 1
  • Smad-specific E3 ubiquitin ligase 1
  • SMAD-specific E3 ubiquitin-protein ligase 1
  • SMURF1

Background

SMURF1 encodes a ubiquitin ligase that is specific for receptor-regulated SMAD proteins in the bone morphogenetic protein (BMP) pathway. A similar protein in Xenopus is involved in embryonic pattern formation. Alternative splicing results in multiple transcript variants encoding different isoforms. An additional transcript variant has been identified, but its full length sequence has not been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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SMURF1 Antibody
[Janelia Fluor® ...
NBP2-41297JF585
SMURF1 Antibody [Janelia Fluor® 585]
Species: Hu, Mu, Rt
Applications: WB, ELISA, IHC

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Bioinformatics

Gene Symbol SMURF1