ILT6/CD85e/LILRA3 Antibody (2E9)

This product is produced by and distributed for Abnova, a company based in Taiwan.

Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and natural killer (NK) cells. All LIRs in subfamily B have an inhibitory function (see, e.g., LILRB1, MIM 604811). LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may initiate stimulatory cascades (see LILRA1, MIM 604810). One member of subfamily A (LILRA3) lacks a transmembrane region and is presumed to be a soluble receptor (Borges et al., 1997 [PubMed 9548455]).[supplied by OMIM]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publications 1 - 6 of 6.

Publications using H00011026-M01	Applications	Species
Hongyan A, Alexander R, Poornima R et al. Nuclear Leukocyte Immunoglobulin-like Receptor A3 Is Monomeric and Is Involved in Multiple Layers of Regulated Gene Expression and Translation. J Proteome Res. 2021-04-01 [PMID: 33793249]
Low HZ, Ahrenstorf G, Pommerenke C et al. TLR8 regulation of LILRA3 in monocytes is abrogated in human immunodeficiency virus infection and correlates to CD4 counts and virus loads. Retrovirology 2016-03-12 [PMID: 26969150]
An H, Lim C, Guillemin GJ et al. Serum Leukocyte Immunoglobulin-Like Receptor A3 (LILRA3) Is Increased in Patients with Multiple Sclerosis and Is a Strong Independent Indicator of Disease Severity; 6.7kbp LILRA3 Gene Deletion Is Not Associated with Diseases Susceptibility. PLoS One 2016-02-12 [PMID: 26871720]
An H, Brettle M, Lee T et al. Soluble LILRA3 promotes neurite outgrowth and synapses formation through high affinity interaction with Nogo 66. J Cell Sci 2016-01-29 [PMID: 26826187]
Lee TH, Mitchell A, Liu Lau S et al. Glycosylation in a mammalian expression system is critical for the production of functionally active leukocyte immunoglobulin-like receptor A3 protein. J Biol Chem. 2013-09-30 [PMID: 24085305]
An H, Chandra V, Piraino B et al. Soluble LILRA3, a Potential Natural Antiinflammatory Protein, Is Increased in Patients with Rheumatoid Arthritis and Is Tightly Regulated by Interleukin 10, Tumor Necrosis Factor-{alpha}, and Interferon-{gamma}. J Rheumatol. 2010-07-01 [PMID: 20595277]

Array H00011026-M01

• ILT6/CD85e/LILRA3 Antibodies
• ILT6/CD85e/LILRA3 Antibody Pair
• ILT6/CD85e/LILRA3 Lysate
• ILT6/CD85e/LILRA3 Proteins and Enzyme