Name: SMURF1 Antibody (1D7)
Brand: Novus Biologicals
SKU: H00057154-M01
Price: 519 USD

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Reactivity	Hu, Mu, RtSpecies Glossary
Applications	WB, ELISA, ICC/IF, IHC, IP
Clone	1D7
Clonality	Monoclonal
Host	Mouse
Conjugate	Unconjugated

Immunogen	SMURF1 (NP_065162, 165 a.a. ~ 268 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. DSGPGRPLSCFMEEPAPYTDSTGAAAGGGNCRFVESPSQDQRLQAQRLRNPDVRGSLQTPQNRPHGHQSPELPEGYEQRTTVQGQVYFLHTQTGVSTWHDPRIP
Specificity	SMURF1 (1D7)
Isotype	IgG2a Kappa
Clonality	Monoclonal
Host	Mouse
Gene	SMURF1
Purity	IgG purified
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Storage	Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer	In 1x PBS, pH 7.4
Preservative	No Preservative
Purity	IgG purified

Publications using H00057154-M01	Applications	Species
Zhu K, Tang Y, Xu X et al. Non-proteolytic ubiquitin modification of PPARg by Smurf1 protects the liver from steatosis PLoS Biol. 2018-12-01 [PMID: 30566427] (WB, Mouse)	WB	Mouse
Murakami K, Etlinger JD., et al. Role of SMURF1 ubiquitin ligase in BMP receptor trafficking and signaling. Cell Signal 2018-11-03 [PMID: 30395943]
Tang Y, Tang L, Xu X et al. Generation of Smurf2 Conditional Knockout Mice Int. J. Biol. Sci. 2018-04-26 [PMID: 29805305] (WB, Mouse)	WB	Mouse
Barnes JW, Kucera ET, Tian L et al. BMPR2 Mutation-independent Mechanisms of Disrupted BMP Signaling in IPAH. Am J Respir Cell Mol Biol 2016-05-17 [PMID: 27187737]
Wang J, Zhang Y, Weng W et al. Impaired phosphorylation and ubiquitination by p70 S6 kinase (p70S6K) and Smad ubiquitination regulatory factor 1 (Smurf1) promote tribbles homolog 2 (TRIB2) stability and carcinogenic property in liver cancer. J Biol Chem. 2013-11-22 [PMID: 24089522] (ICC/IF, IF/IHC, Human)	ICC/IF, IF/IHC	Human
Du JX, Hagos EG, Nandan MO et al. The E3 ubiquitin ligase, SMAD ubiquitination regulatory factor 2, negatively regulates Kruppel-like factor 5. J Biol Chem. 2011-09-27 [PMID: 21953463]
Murakami K, Mathew R, Huang J et al. Smurf1 ubiquitin ligase causes downregulation of BMP receptors and is induced in monocrotaline and hypoxia models of pulmonary arterial hypertension. Exp Biol Med (Maywood) 235(7):805-13. 2010-07-01 [PMID: 20558834]

SMURF1 Antibody (1D7)

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Bioinformatics

Gene Symbol	SMURF1
Entrez	57154(Human)
OMIM	605568(Human)
Uniprot	NP_065162(Human)