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S1P1/EDG-1 Antibody (713412) [Biotin]

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HEK293 human embryonic kidney cell line transfected with mouse S1P1/EDG-1 and eGFP was stained with (A) Rat Anti-Mouse S1P1/EDG-1 Biotinylated Monoclonal Antibody (Catalog # FAB7089B) or (B) Rat IgG2A isotype control antibody (Catalog # IC006B) followed by Streptavidin-Allophycocyanin (Catalog # F0050). View our protocol for Staining Membrane-associated Proteins.
HEK293 human embryonic kidney cell line transfected with mouse S1P1/EDG-1 and eGFP was stained with (A) Rat Anti-Mouse S1P1/EDG-1 Biotinylated Monoclonal Antibody (Catalog # FAB7089B) or (B) Rat IgG2A isotype control ...read more
Mouse thymocytes were stained with (A) Rat Anti-Mouse S1P1/EDG-1 Biotinylated Monoclonal Antibody (Catalog # FAB7089B) or (B) Rat IgG2A isotype control antibody (Catalog # IC006B) followed by ...read more

Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow
Clone
713412
Clonality
Monoclonal
Host
Rat
Conjugate
Biotin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB7089U-100UG
Alexa Fluor 405
FAB7089V-100UG
Alexa Fluor 488
FAB7089G-100ug
Alexa Fluor 532
FAB7089X
Alexa Fluor 594
FAB7089T-100UG
Alexa Fluor 647
FAB7089R-100UG
Alexa Fluor 700
FAB7089N
Alexa Fluor 750
FAB7089S-100UG
Allophycocyanin
FAB7089A-100UG
Allophycocyanin/Cy7
FAB7089APCCY7
CoraFluor 1
FAB7089CL1
DyLight 350
FAB7089D
DyLight 405
FAB7089E
DyLight 488
FAB7089K
DyLight 550
FAB7089L
DyLight 594
FAB7089M
DyLight 650
FAB7089W
DyLight 680
FAB7089Y
DyLight 755
FAB7089Z
FITC
FAB7089F
HRP
FAB7089H
Janelia Fluor 525
FAB7089JF525
Janelia Fluor 549
FAB7089I
Janelia Fluor 585
FAB7089JF585
Janelia Fluor 635
FAB7089JF635
Janelia Fluor 646
FAB7089J
Janelia Fluor 669
FAB7089JF669
PE/Atto594
FAB7089PEATT594
PE/Cy5.5
FAB7089PECY55
PE/Cy7
FAB7089PECY7
PerCP
FAB7089C
Phycoerythrin
FAB7089P-100UG
Unconjugated
MAB7089
mFluor Violet 450 SE
FAB7089MFV450
mFluor Violet 500 SE
FAB7089MFV500
mFluor Violet 610 SE
FAB7089MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB7089
Carrier Free
MAB7089
Carrier Free
FAB7089N
Carrier Free
MAB7089-SP
Carrier Free
FAB7089V-100UG
Carrier Free
FAB7089U-100UG
Carrier Free
FAB7089T-100UG
Carrier Free
FAB7089S-100UG
Carrier Free
FAB7089R-100UG
Carrier Free
FAB7089G-100ug
Carrier Free
FAB7089P-100UG
Carrier Free
FAB7089A-100UG
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S1P1/EDG-1 Antibody (713412) [Biotin] Summary

Immunogen
Mouse S1P1/EDG‑1 synthetic peptide (T4-H28)
Accession # O08530
Specificity
Detects mouse S1P1/EDG‑1 peptide in direct ELISAs.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
S1PR1
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
Readout System

Packaging, Storage & Formulations

Storage
Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for S1P1/EDG-1 Antibody (713412) [Biotin]

  • CD363 antigen
  • CD363
  • CHEDG1
  • D1S3362
  • EDG1
  • EDG-1
  • EDG1edg-1
  • Endothelial differentiation G-protein coupled receptor 1
  • endothelial differentiation, sphingolipid G-protein-coupled receptor, 1
  • FLJ58121
  • S1P receptor 1
  • S1P receptor Edg-1
  • S1P1
  • S1P1ECGF1
  • S1PR1
  • sphingosine 1-phosphate receptor 1
  • sphingosine 1-phosphate receptor EDG1
  • Sphingosine 1-phosphate receptor Edg-1
  • sphingosine-1-phosphate receptor 1

Background

S1P1 (sphingosine 1-phosphate receptor-1), also known as EDG-1 (endothelial differentiation, G-protein coupled receptor-1) or S1PR1 (sphingosine-1-phosphate receptor 1) is a widely expressed, 37-40 kDa, G protein coupled receptor within the S1P subfamily of the EDG family. S1P1 is one of five receptors for the bioactive lipid S1P and mediates most of S1P effects on angiogenesis, vascular maturation, and cell migration, especially T cell egress from lymphoid organs. Human and mouse S1P1 share 84% amino acid identity within the N-terminal extracellular portion used as an immunogen.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol S1PR1
Uniprot