S100B Antibody [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

S100B belongs to the S100 subgroup of the EF-hand family of Ca²⁺ binding proteins. It is a homodimer that is expressed primarily in the brain by astrocytes, oligodendrocytes and Schwann cells. S100B has multiple intracellular functions, but can also be secreted from cells to exert extracellular functions. Some of the extracellular functions of S100B may be mediated by RAGE (receptor for advanced glycation end products). Blood levels of S100B can be used to monitor the extent of brain injury and malignant melanoma.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 4 applications: ELISA Development, IHC, Immunohistochemistry, Western Blot.

Showing Publications 1 - 6 of 6.

Publications using AF1820	Applications	Species
Sokolova, D;Ghansah, SA;Puletti, F;Georgiades, T;De Schepper, S;Zheng, Y;Crowley, G;Wu, L;Rueda-Carrasco, J;Koutsiouroumpa, A;Muckett, P;Freeman, OJ;Khakh, BS;Hong, S; Astrocyte-derived MFG-E8 facilitates microglial synapse elimination in Alzheimer's disease mouse models bioRxiv : the preprint server for biology 2024-09-01 [PMID: 39257734] (Immunohistochemistry, Human)	Immunohistochemistry	Human
Wang, Y;Peng, J;Song, C;Yang, Y;Qin, T; Zinc finger and SCAN domain-containing 18 suppresses the proliferation, self-renewal, and drug resistance of glioblastoma cells Heliyon 2023-06-01 [PMID: 37389038] (Western Blot, Human)	Western Blot	Human
P Yuan, M Zhang, L Tong, TM Morse, RA McDougal, H Ding, D Chan, Y Cai, J Grutzendle PLD3 affects axonal spheroids and network defects in Alzheimer's disease Nature, 2022-11-30;612(7939):328-337. 2022-11-30 [PMID: 36450991] (IHC, Mouse)	IHC	Mouse
Kyujin Hwang, Kwangsoo Jung, Il-Sun Kim, Miri Kim, Jungho Han, Joohee Lim et al. Glial Cell Line-derived Neurotrophic Factor-overexpressing Human Neural Stem/Progenitor Cells Enhance Therapeutic Efficiency in Rat with Traumatic Spinal Cord Injury Experimental Neurobiology 12/31/2019 [PMID: 31902156]
Jay T, Hirsch A, Broihier M, Miller C, Neilson L, Ransohoff R, Lamb B, Landreth G Disease Progression-Dependent Effects of TREM2 Deficiency in a Mouse Model of Alzheimer's Disease. J Neurosci, 2017-01-18;37(3):637-647. 2017-01-18 [PMID: 28100745] (IHC, Mouse)	IHC	Mouse
Qi LY, Xiu MH, Chen da C, Wang F, Kosten TA, Kosten TR, Zhang XY Increased serum S100B levels in chronic schizophrenic patients on long-term clozapine or typical antipsychotics. Neurosci. Lett., 2009-06-17;462(2):113-7. 2009-06-17 [PMID: 19539717] (ELISA Development, Human)	ELISA Development	Human

Images	Ratings	Applications	Species	Date	Details
Enlarge	5 reviewed by: Verified Customer	IHC-P	Mouse	08/18/2017	View Summary Application Immunohistochemistry-Paraffin Sample Tested mouse skin tissue Species Mouse Lot JTR021706B Comments Comments 1.Tissue: formalin fixed paraffin embedded mouse skin tissue 2.Antigen retrieval: 0.01 M Citric Acid, 0.05% Tween-20 3.First antibody: Goat anti s100b (AF1820), 1:100 dilution overnight at 4 °C 4.Secondary antibody- Bio- Dondey anti Goat, 1:200 room temperature 1 hours 5.Kits used : Vectorstain ABC kit (cat: PK-4000) and DAB staining kit (Brown, cat: SK4100) 6.Counterstained with hematoxylin (blue), only nerve and hair follicle are positive.

Array AF1820

• S100B Antibodies
• S100B Antibody Pair
• S100B ELISA Kit
• S100B Lysate
• S100B Proteins
• S100B Proteins and Enzyme
• S100B ELISA