Melan-A/MART-1 Antibody (A19-P) Summary
Description
This antibody is immunoaffinity purified with immunogenic peptide as a ligand.
Additional Information
Recombinant Monoclonal Antibody.
Immunogen
Peptide derived from C-terminal sequence of human Melan-A/MART-1. Antibody recognizes the epitope between Glu105 - Pro115.
Epitope
Glu105 - Pro115
Specificity
This antibody is specific for the C terminal portions of Melan-A
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
MLANA
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Applications/Dilutions
Dilutions
Immunocytochemistry/ Immunofluorescence Immunohistochemistry 1:100 - 1:200 Immunohistochemistry-Paraffin 1:100 - 1:200
Reviewed Applications
Read 4 Reviews rated 4.8
using NBP1-30151 in the following applications:
Publications
Read Publications using NBP1-30151 in the following applications:
Reactivity Notes
Mouse reactivity reported in scientific literature (PMID: 26547111). Use in Canine reported in secitific publication PMID: 32423311
Packaging, Storage & Formulations
Storage
Store at 4C. Do not freeze.
Buffer
20mM Tris-HCl (pH 8.0) and 20mg/ml BSA
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified
Notes
This antibody is immunoaffinity purified with immunogenic peptide as a ligand.
Alternate Names for Melan-A/MART-1 Antibody (A19-P)
Background
MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Applications: IHC, IHC-P, WB
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Applications: CyTOF-ready, ELISA, Flow, Func, IHC, IHC-Fr, IHC-P (-), IP
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Applications: IHC, WB
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Applications: BA
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Applications: ELISA, Flow, ICC/IF, IHC, IP, WB
Species: Bv, Ca, Ch, Eq, Hu, Mu, Po, Rt
Applications: ICC/IF, IHC, IHC-Fr, IHC-P, WB
Species: Hu, Mu
Applications: ICC/IF, IHC, IHC-P, WB
Species: Hu
Applications: Flow, ICC/IF, IHC, IHC-P, WB
Species: Hu
Applications: ICC/IF, IHC, IHC-P, WB
Species: Hu, Mu
Applications: Flow-IC, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, WB
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Applications: IHC
Publications for Melan-A/MART-1 Antibody (NBP1-30151)(22)
We have publications tested in 4 confirmed species: Human, Mouse, Canine, Monkey.
We have publications tested in 5 applications: ICC/IF, IF/IHC, IHC-Fr, IHC-P, Immunohistochemistry-Paraffin.
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Showing Publications 1 -
10 of 22.
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Publications using NBP1-30151
Applications
Species
Aoki H, Tomita H, Hara A, Kunisada T Postnatal expression of Kit ligand affects pigmentation of the epidermis The Journal of investigative dermatology 2023-07-21 [PMID: 37482288]
Kruse B, Buzzai AC, Shridhar N et al. CD4+ T cell-induced inflammatory cell death controls immune-evasive tumours Nature 2023-06-01 [PMID: 37316667] (IHC-P, Human) Details: IHC-P: 1:500
IHC-P
Human
Dietsch, B;Weller, C;Sticht, C;de la Torre, C;Kramer, M;Goerdt, S;G�raud, C;Wohlfeil, SA; Hepatic passaging of NRAS-mutant melanoma influences adhesive properties and metastatic pattern BMC cancer 2023-05-13 [PMID: 37179302] (ICC/IF, Mouse)
ICC/IF
Mouse
Estrada J, Zhan J, Mitchell P et al. OncoVEXmGM-CSFexpands tumor antigen-specific CD8+ T-cell response in preclinical models Journal for immunotherapy of cancer 2023-05-01 [PMID: 37164449] (Immunohistochemistry-Paraffin, Mouse)
Immunohistochemistry-Paraffin
Mouse
Eichhoff OM, Stoffel CI, K�sler J et al. ROS Induction Targets Persister Cancer Cells with Low Metabolic Activity in NRAS-Mutated Melanoma Cancer research 2023-03-22 [PMID: 36946761]
Hosoya M, Kitama T, Iwabu K et al. Development of the stria vascularis in the common marmoset, a primate model Scientific reports 2022-11-17 [PMID: 36396805] (IHC-Fr, Monkey) Details: Dilution used in IHC-Fr 1:500
IHC-Fr
Monkey
Lee JH, Ahn Y, Lee HE et al. Wearable Surface-Lighting Micro-Light-Emitting Diode Patch for Melanogenesis Inhibition Advanced healthcare materials 2022-10-03 [PMID: 36189834] (IF/IHC)
IF/IHC
Eshiba S, Namiki T, Mohri Y Et al. Stem cell spreading dynamics intrinsically differentiate acral melanomas from nevi Cell reports 2021-08-03 [PMID: 34348144]
van Beelen ESA, van der Valk WH, de Groot JCMJ et al. Migration and fate of vestibular melanocytes during the development of the human inner ear Dev Neurobiol 2020-10-19 [PMID: 33075185] (IF/IHC, Human)
IF/IHC
Human
Nakano S, Abe Y, Nakajima K et al. Establishment of a mouse model for post-inflammatory hyperpigmentation Pigment Cell Melanoma Res 2020-07-04 [PMID: 32623834] (IF/IHC)
IF/IHC
Rahman H, Kumar D, Liu T et al. Aspirin protects melanocytes and keratinocytes against UVB-induced DNA damage in vivo J. Invest. Dermatol. 2020-06-19 [PMID: 32569596]
Touil Y, Segaoula Z, Thuru X et al. Aggressiveness potential of spontaneous canine mucosal melanoma can dictate distinct cancer stem cell compartment behaviors in regard to their initial size and expansion abilities Stem Cells Dev. 2020-05-18 [PMID: 32423311] (IF/IHC, Canine)
IF/IHC
Canine
Boukhedouni N, Martins C, Darrigade AS et al. Type-1 cytokines regulate MMP-9 production and E-cadherin disruption to promote melanocyte loss in vitiligo JCI Insight 2020-06-04 [PMID: 32369451] (IHC-P, Human)
IHC-P
Human
Pai CS, Huang JT, Lu X et al. Clonal Deletion of Tumor-Specific T Cells by Interferon-g Confers Therapeutic Resistance to Combination Immune Checkpoint Blockade Immunity 2019-02-19 [PMID: 30737146] (IF/IHC, Mouse)
IF/IHC
Mouse
Kimeswenger S, Sterniczky B, kramer A et al. Impact of infrared radiation on UVB-induced skin tumourigenesis in wild type C57BL/6 mice. Photochem. Photobiol. Sci. 2018-10-24 [PMID: 30357250] (Mouse)
Mouse
De Luca DA, Sterniczky B, Kimeswenger S et al. Ultraviolet radiation induces Melan-A-expressing cells in interfollicular epidermis in wild-type mice Arch. Dermatol. Res. 2018-05-17 [PMID: 29774387] (IHC-P, Mouse)
IHC-P
Mouse
Cassidy PB, Liu T, Florell SR et al. A phase II randomized placebo-controlled trial of oral N-acetylcysteine for protection of melanocytic nevi against UV-induced oxidative stress in vivo Cancer Prev Res (Phila). 2016-12-04 [PMID: 27920018] (IHC-P, Human)
IHC-P
Human
Goldschmidt BS, Viator JA. Capture and Isolation of Circulating Melanoma Cells Using Photoacoustic Flowmetry. Methods Mol. Biol. 2015-12-13 [PMID: 26659796]
Abe Y, Okamura K, Kawaguchi M et al. Rhododenol-induced leukoderma in a mouse model mimicking Japanese skin. J. Dermatol. Sci. 2015-10-27 [PMID: 26547111] (IHC-P, Mouse)
IHC-P
Mouse
Locher H, de Groot JC, van Iperen L et al. Development of the stria vascularis and potassium regulation in the human fetal cochlea: Insights into hereditary sensorineural hearing loss. Dev Neurobiol 2015-11-01 [PMID: 25663387] (IHC-P, Human)
IHC-P
Human
Locher H, Frijns J H et al. TUBB3: neuronal marker or melanocyte mimic? Cell Transplant 2013-10-25 [PMID: 24152858] (IF/IHC, Human)
IF/IHC
Human
Locher H, de Rooij KE, de Groot JC et al. Class III beta-tubulin, a novel biomarker in the human melanocyte lineage. Differentiation. 2013-04-01 [PMID: 23817083] (IHC-P, ICC/IF, Mouse, Human)
IHC-P, ICC/IF
Mouse, Human
Show All 22 Publications.
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Reviews for Melan-A/MART-1 Antibody (NBP1-30151) (4)
4.8 4
Average Rating: 4.8
(Based on 4 reviews)
We have 4 reviews tested in 2 species: Human, Mouse.
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Reviews using NBP1-30151:
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Ratings
Applications
Species
Date
Details
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5
reviewed by: Verified Customer
IHC-P
Human
10/30/2019
Summary
Application Immunohistochemistry-Paraffin Sample Tested human fetal inner ear Species Human Lot DB050-01-06B
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4
reviewed by: Verified Customer
ICC
Mouse
09/02/2013
Summary
Application Immunocytochemistry Sample Tested Mouse melanocyte cell line Species Mouse
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5
reviewed by: Verified Customer
ICC
Human
09/02/2013
Summary
Application Immunocytochemistry Sample Tested Human hair follicle culture Species Human
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5
reviewed by: Verified Customer
IHC-P
Human
09/02/2013
Summary
Application Immunohistochemistry-Paraffin Sample Tested Human adult facial skin Species Human
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