Home » RUNX3/CBFA3 » RUNX3/CBFA3 Antibodies » RUNX3/CBFA3 Antibody (2B10E8) [Janelia Fluor® 585]
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RUNX3/CBFA3 Antibody (2B10E8) [Janelia Fluor® 585]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, IHC
Clone
2B10E8
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 585

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-22391AF350
Alexa Fluor 405
NBP2-22391AF405
Alexa Fluor 488
NBP2-22391AF488
Alexa Fluor 532
NBP2-22391AF532
Alexa Fluor 594
NBP2-22391AF594
Alexa Fluor 647
NBP2-22391AF647
Alexa Fluor 700
NBP2-22391AF700
Alexa Fluor 750
NBP2-22391AF750
Allophycocyanin
NBP2-22391APC
Biotin
NBP2-22391B
CoraFluor 1
NBP2-22391CL1
DyLight 350
NBP2-22391UV
DyLight 405
NBP2-22391V
DyLight 488
NBP2-22391G
DyLight 550
NBP2-22391R
DyLight 594
NBP2-22391DL594
DyLight 650
NBP2-22391C
DyLight 680
NBP2-22391FR
DyLight 755
NBP2-22391IR
FITC
NBP2-22391F
HRP
NBP2-22391H
Janelia Fluor 525
NBP2-22391JF525
Janelia Fluor 635
NBP2-22391JF635
Janelia Fluor 669
NBP2-22391JF669
PE
NBP2-22391PE
PerCP
NBP2-22391PCP
Unconjugated
NBP2-22391
mFluor Violet 450 SE
NBP2-22391MFV450
mFluor Violet 500 SE
NBP2-22391MFV500
mFluor Violet 610 SE
NBP2-22391MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-22391
BSA Free
NBP2-22391
BSA Free
NBP2-22391SS
Azide and BSA Free
NBP2-80934
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RUNX3/CBFA3 Antibody (2B10E8) [Janelia Fluor® 585] Summary

Immunogen
Amino acids 126-310 of human Runx3 were used as the immunogen for this antibody.
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
RUNX3
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for RUNX3/CBFA3 Antibody (2B10E8) [Janelia Fluor® 585]

  • Acute myeloid leukemia 2 protein
  • AML2
  • AML2SL3/AKV core-binding factor alpha C subunit
  • CBFA3
  • CBFA3MGC16070
  • CBF-alpha-3
  • PEA2 alpha C
  • PEA2-alpha C
  • PEBP2 alpha C
  • PEBP2A3
  • PEBP2A3FLJ34510
  • PEBP2AC
  • PEBP2-alpha C
  • runt domain, alpha subunit 3
  • runt-related transcription factor 3
  • RUNX3
  • SL3-3 enhancer factor 1 alpha C subunit
  • transcription factor AML2

Background

RUNX3 binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, lck, IL-3 and GM-CSF promoters. RUNX3 consists of a heterodimer of an alpha and a beta subunit. The alpha subunit binds DNA as a monomer through the Runt domain. DNA-binding is increased by heterodimerization.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol RUNX3