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REXO1 Antibody [Janelia Fluor® 635]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 635

Order Details

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REXO1 Antibody [Janelia Fluor® 635] Summary

Immunogen
Produced in rabbits immunized with E. coli-derived Human REXO1 fragment.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
REXO1
Purity
Antigen and protein A Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Antigen and protein A Affinity-purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for REXO1 Antibody [Janelia Fluor® 635]

  • EC 3.1
  • ELOABP1elongin A-binding protein 1
  • EloA-BP1REX1
  • Elongin-A-binding protein 1
  • KIAA1138elongin A binding protein 1
  • REX1, RNA exonuclease 1 homolog (S. cerevisiae)
  • TCEB3BP1RNA exonuclease 1 homolog
  • transcription elongation factor B polypeptide 3 binding protein 1
  • Transcription elongation factor B polypeptide 3-binding protein 1

Background

REXO1 or Elongin A-binding protein 1 (EloA-BP1) is an exonuclease domain-containing protein that can bind to Elongin. The Elongin complex stimulates the rate of transcription elongation by RNA polymerase II by suppressing the transient pausing of the polymerase at many sites along the DNA template. REXO1 is composed of 1221 amino acids and its mRNA is ubiquitously expressed. EloA-BP1 is capable of binding not only the NH(2)-terminal approximately 120 amino acid region of Elongin A, but also that of SII. Although REXO1 had no detectable effect on the rate of transcription elongation in vitro, it may play some role in the regulation of elongation in vivo.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Additional REXO1 Products

Array NBP2-98052JF635

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Bioinformatics

Gene Symbol REXO1