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Prokineticin R1/PROKR1 Antibody (420849)

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Human blood‑derived monocytes were stained with Human Prokineticin R1/PKR1 Monoclonal Antibody (Catalog # MAB4655, filled histogram) or isotype control antibody (Catalog # MAB0041, open histogram), followed by Allophycocyanin-conjugated Anti-Mouse IgG F(ab')2 Secondary Antibody (Catalog # F0101B).
Human blood‑derived monocytes were stained with Human Prokineticin R1/PKR1 Monoclonal Antibody (Catalog # MAB4655, filled histogram) or isotype control antibody (Catalog # MAB0041, open histogram), ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
420849
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB4655U-100UG
Alexa Fluor 405
FAB4655V-100UG
Alexa Fluor 488
FAB4655G-100UG
Alexa Fluor 532
FAB4655X
Alexa Fluor 594
FAB4655T-100UG
Alexa Fluor 647
FAB4655R-100UG
Alexa Fluor 700
FAB4655N-100UG
Alexa Fluor 750
FAB4655S-100UG
Allophycocyanin
FAB4655A
Allophycocyanin/Cy7
FAB4655APCCY7
Biotin
FAB4655B
CoraFluor 1
FAB4655CL1
DyLight 350
FAB4655D
DyLight 405
FAB4655E
DyLight 488
FAB4655K
DyLight 550
FAB4655L
DyLight 594
FAB4655M
DyLight 650
FAB4655W
DyLight 680
FAB4655Y
DyLight 755
FAB4655Z
FITC
FAB4655F
HRP
FAB4655H
Janelia Fluor 525
FAB4655JF525
Janelia Fluor 549
FAB4655I
Janelia Fluor 585
FAB4655JF585
Janelia Fluor 635
FAB4655JF635
Janelia Fluor 646
FAB4655J
Janelia Fluor 669
FAB4655JF669
PE
FAB4655P
PE/Atto594
FAB4655PEATT594
PE/Cy5.5
FAB4655PECY55
PE/Cy7
FAB4655PECY7
PerCP
FAB4655C
mFluor Violet 450 SE
FAB4655MFV450
mFluor Violet 500 SE
FAB4655MFV500
mFluor Violet 610 SE
FAB4655MFV610
View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
MAB4655-SP
Carrier Free
FAB4655V-100UG
Carrier Free
FAB4655U-100UG
Carrier Free
FAB4655T-100UG
Carrier Free
FAB4655S-100UG
Carrier Free
FAB4655R-100UG
Carrier Free
FAB4655N-100UG
Carrier Free
FAB4655G-100UG
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Prokineticin R1/PROKR1 Antibody (420849) Summary

Immunogen
NS0 mouse myeloma cell line transfected with human Prokineticin R1/PKR1
Met1-Lys393
Accession # Q8TCW9
Specificity
Detects human Prokineticin R1/PKR1. Stains human Prokineticin R1/PKR1 transfectants but not irrelevant transfectants.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
PROKR1
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry 2.5 ug/10^6 cells

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Prokineticin R1/PROKR1 Antibody (420849)

  • G protein-coupled receptor 73
  • G protein-coupled receptor ZAQ
  • GPR73
  • GPR73a
  • GPR73aG-protein coupled receptor 73
  • PKR1
  • PK-R1
  • PKR1G-protein coupled receptor ZAQ
  • Prokineticin R1
  • prokineticin receptor 1
  • ProkineticinR1
  • PROKR1
  • ZAQ

Background

Prokineticin Receptor 1 (PKR1), also called ZAQ or GPR73a (G-protein coupled receptor 73a), is a 7-transmembrane glycoprotein of the GPCR family. The extracellular portions of human PKR1 share 81% and 78% aa identity with corresponding portions of mouse PKR1 and human PKR2, with non-identity mainly in the N‑terminal sequences. Both PKR1 and PKR2 mediate the effects of prokineticins 1 and 2. This includes mitogenic regulation of angiogenesis in endocrine glands and stimulation of contraction in gastrointestinal smooth muscle.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PROKR1
Uniprot