ZAK Antibody (3G5)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publications 1 - 3 of 3.

Publications using H00051776-M03	Applications	Species
Nyati S, Chator A, Schinske K et al. A Requirement for ZAK Kinase Activity in Canonical TGF-B Signaling. Transl Oncol 2016-10-23 [PMID: 27783979]
Perez Lopez I, Cariolato L, Maric D et al. A-Kinase Anchoring Protein Lbc Coordinates a p38 Activating Signaling Complex Controlling Compensatory Cardiac Hypertrophy. Mol Cell Biol. 2013-05-28 [PMID: 23716597]
Cariolato L, Cavin S, Diviani D. AKAP-LBC anchors a PKN-based signaling complex involved in alpha1-adrenergic receptor-induced p38 activation. J Biol Chem. 2011-01-11 [PMID: 21224381]

Array H00051776-M03

• ZAK Antibodies
• ZAK Lysates
• ZAK Protein