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Vanilloid R1/TRPV1 Antibody - BSA Free

Images

 
Immunohistochemistry: Vanilloid R1/TRPV1 Antibody [NBP1-71774] - The Vanilloid R1/TRPV1+ and Vanilloid R1/TRPV1+CD4+ immune cells in patients with allergic rhinitis. Immunohistochemical staining of Vanilloid R1/TRPV1 ...read more
Immunocytochemistry/ Immunofluorescence: Vanilloid R1/TRPV1 Antibody [NBP1-71774] - TRPV1 antibody was tested at 1:50 in HeLa cells with FITC (green). Nuclei were counterstained with DAPI (blue).
Immunohistochemistry: Vanilloid R1/TRPV1 Antibody [NBP1-71774] - Analysis of TRPV1 in mouse dorsal root ganglion using DAB with hematoxylin counterstain.
Immunohistochemistry-Paraffin: Vanilloid R1/TRPV1 Antibody [NBP1-71774] - Human stomach tissue. Positive staining can be observed in gastric neurons. Image from verified customer review.
The TRPV1+ and TRPV1+CD4+ immune cells in patients with allergic rhinitisA. Immunohistochemical staining of TRPV1 (single staining) and CD4/TRPV1 (double staining) in patients with allergic rhinitis compared with ...read more

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1.0 mg/ml

Order Details

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Vanilloid R1/TRPV1 Antibody - BSA Free Summary

Immunogen
A genomic peptide made to a C-terminal region of the human TRPV1 protein (within residues 725-839). [Swiss-Prot# Q8NER1]
Localization
Cell junction: synapse. Multi-pass membrane protein.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TRPV1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:50-1:100
  • Immunohistochemistry 1:200
  • Immunohistochemistry-Paraffin 1:200
Application Notes
This TRPV1 antibody is useful for ICC/IF and IHC-paraffin embedded tissues. Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended.
Reviewed Applications
Read 1 Review rated 5
using
NBP1-71774 in the following applications:

Publications
Read Publications using
NBP1-71774 in the following applications:

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Notes

Manufactured by Genomic Antibody Technology™. GAT FAQs

Alternate Names for Vanilloid R1/TRPV1 Antibody - BSA Free

  • Capsaicin Receptor
  • Osm-9-like TRP channel 1
  • OTRPC1
  • transient receptor potential cation channel subfamily V member 1
  • transient receptor potential cation channel, subfamily V, member 1
  • transient receptor potential vanilloid 1a
  • transient receptor potential vanilloid 1b
  • TRPV1
  • Vanilloid R1
  • Vanilloid receptor 1
  • vanilloid receptor subtype 1
  • VanilloidR1
  • VR1
  • VR1DKFZp434K0220

Background

TRPV1, a ligand-gated cation channel expressed in peripheral nociceptors, induces pain when activated by capsaicin. TRPV1 affects the inhibitory control of neurons by integrating multiple noxious signals, which is critical in chronic pain. Blocking TRPV1 is becoming a more common approach to suppression of pathological pain. When inflammation is present, TRPV1 causes an itch response. Dietary salt content can affect the concentration and activity of TRPV1, which in turn can affect kidney activities resulting in renin regulation. TRPV1 is also critically involved in thermal activation and detection of infrared radiation. Finally, TRPV1 is dysfunctional in hypertrophic hearts.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Vanilloid R1/TRPV1 Antibody (NBP1-71774)(12)

We have publications tested in 4 confirmed species: Human, Mouse, Marmoset, Primate.

We have publications tested in 6 applications: IF/IHC, IHC, IHC-Fr, IHC-P, Immunohistochemistry-Frozen, WB.


Filter By Application
IF/IHC
(1)
IHC
(1)
IHC-Fr
(1)
IHC-P
(2)
Immunohistochemistry-Frozen
(1)
WB
(1)
All Applications
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Human
(4)
Mouse
(2)
Marmoset
(1)
Primate
(2)
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Showing Publications 1 - 10 of 12. Show All 12 Publications.
Publications using NBP1-71774 Applications Species
Kumar V, Kingsley D, Madhurakkat Perikamana S et al. Self-assembled innervated vasculature-on-a-chip to study nociception Biofabrication 2023-04-13 [PMID: 36996841] (WB) WB
Hovhannisyan AH, Lindquist KA, Belugin S et al. Sensory innervation of masseter, temporal and lateral pterygoid muscles in common marmosets bioRxiv : the preprint server for biology 2023-02-12 [PMID: 36798270] (IHC-Fr, Marmoset, Primate)

Details:
Dilution used in IHC-Fr 1:200
IHC-Fr Marmoset, Primate
Ilhan HD, Unal B, Ayaz Y, Erin N Changes in TRPV1 Expression as Well as Substance P and Vasoactive Intestinal Peptide Levels Are Associated with Recurrence of Pterygium International journal of molecular sciences 2022-12-10 [PMID: 36555331] (IHC-P, Human)

Details:
Dilution used in IHC-P 1:100
IHC-P Human
Samivel R, Kim DW, Son HR et al. The role of TRPV1 in the CD4+ T cell-mediated inflammatory response of allergic rhinitis. Oncotarget. 2016-01-05 [PMID: 26700618] (IF/IHC, Human, Mouse) IF/IHC Human, Mouse
Tram M, Ibrahim T, Hovhannisyan A et al. Lingual innervation in male and female marmosets Neurobiology of Pain 2023-08-01 (Immunohistochemistry-Frozen, Primate)

Details:
Species-marmoset (Callithrix jacchus)
Immunohistochemistry-Frozen Primate
Meilinn Tram, Tarek Ibrahim, Anahit Hovhannisyan, Armen Akopian, Shivani Ruparel Lingual innervation in male and female marmosets Neurobiology of Pain 2023-05-31 [PMID: 38099285]
Warfield R, Robinson JA, Podgorski RM et al. Neuroinflammation in the Dorsal Root Ganglia and Dorsal Horn Contributes to Persistence of Nociceptor Sensitization in SIV-Infected Antiretroviral Therapy-Treated Macaques The American journal of pathology 2023-09-19 [PMID: 37734588] (IHC) IHC
Moutafidi A, Gatzounis G, Zolota V, Assimakopoulou M Heat shock factor 1 in brain tumors: a link with transient receptor potential channels TRPV1 and TRPA1 Journal of molecular histology 2021-09-30 [PMID: 34591198]
Bi X, Xu Y, Li T et al. Chronic stress augments esophageal inflammation, and alters the expression of transient receptor potential vanilloid 1 and protease-activated receptor 2 in a murine model Mol Med Rep 2019-06-01 [PMID: 31059059]
Rizopoulos T, Papadaki-Petrou H, Assimakopoulou M. Expression Profiling of the Transient Receptor Potential Vanilloid (TRPV) Channels 1, 2, 3 and 4 in Mucosal Epithelium of Human Ulcerative Colitis. Cells. 2018-06-15 [PMID: 29914124] (IHC-P, Human) IHC-P Human
Show All 12 Publications.

Review for Vanilloid R1/TRPV1 Antibody (NBP1-71774) (1) 51

Average Rating: 5
(Based on 1 review)
We have 1 review tested in 1 species: Human.

Reviews using NBP1-71774:
Filter by Applications
IHC-P
(1)
All Applications
Filter by Species
Human
(1)
All Species
Images Ratings Applications Species Date Details
Immunohistochemistry-Paraffin Vanilloid R1/TRPV1 NBP1-71774
Enlarge
5
reviewed by:
Feng Li
IHC-P Human 01/23/2019
View

Summary

ApplicationImmunohistochemistry-Paraffin
Sample TestedStomach tissue
SpeciesHuman
LotA-4

Product General Protocols

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Video Protocols

ICC/IF Video Protocol

FAQs for Vanilloid R1/TRPV1 Antibody (NBP1-71774) (0)

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Secondary Antibodies

 

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Recent Reviews

5
5
1
4
0
3
0
2
0
1
0

Feng Li
01/23/2019
Application: IHC-P
Species: Human

Bioinformatics

Gene Symbol TRPV1
Entrez
Uniprot