PRMT6 Antibody Blocking Peptide Summary
Specificity |
This peptide is specific for NB100-56642 only. |
Protein/Peptide Type |
Antibody Blocking Peptide |
Gene |
PRMT6 |
Applications/Dilutions
Dilutions |
|
Application Notes |
This peptide is useful as a blocking peptide for NB100-56642. For further blocking peptide related protocol, click here. |
Packaging, Storage & Formulations
Storage |
Store at -80C. Avoid freeze-thaw cycles. |
Buffer |
Peptide dissolved in dH20. Contains no BSA. |
Preservative |
No Preservative |
Concentration |
1 mg/ml |
Alternate Names for PRMT6 Antibody Blocking Peptide
Background
PRMT6 severely impairs the function of HIV-1 Rev. PRMT6 is a protein arginine N-methyltransferase, and catalyzes the sequential transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation is a prevalent post-translational modification in eukaryotic cells that has been implicated in signal transduction, the metabolism of nascent pre-RNA, and the transcriptional activation processes. In addition, PRMT6 displays automethylation activity; it is the first PRMT to do so. PRMT6 has been shown to act as a restriction factor for HIV replication.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are
guaranteed for 3 months from date of receipt.
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