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PDGFR alpha Antibody (APA5) [PE/Cy5.5]

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications Flow
Clone
APA5
Clonality
Monoclonal
Host
Rat
Conjugate
PE/Cy5.5

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP1-43350AF350
Alexa Fluor 405
NBP1-43350AF405
Alexa Fluor 488
NBP1-43350AF488
Alexa Fluor 532
NBP1-43350AF532
Alexa Fluor 594
NBP1-43350AF594
Alexa Fluor 647
NBP1-43350AF647
Alexa Fluor 700
NBP1-43350AF700
Alexa Fluor 750
NBP1-43350AF750
Allophycocyanin
NBP1-43350APC
Allophycocyanin/Cy7
NBP1-43350APCCY7
Biotin
NBP1-43581-0.1mg
Biotin
NBP1-43581-0.025mg
CoraFluor 1
NBP1-43350CL1
DyLight 350
NBP1-43350UV
DyLight 405
NBP1-43350V
DyLight 488
NBP1-43350G
DyLight 550
NBP1-43350R
DyLight 594
NBP1-43350DL594
DyLight 650
NBP1-43350C
DyLight 680
NBP1-43350FR
DyLight 755
NBP1-43350IR
FITC
NBP1-43350F
HRP
NBP1-43350H
Janelia Fluor 525
NBP1-43350JF525
Janelia Fluor 549
NBP1-43350JF549
Janelia Fluor 646
NBP1-43350JF646
Janelia Fluor 669
NBP1-43350JF669
PE
NBP1-43350PE
PE/Atto594
NBP1-43350PEATT594
PE/Cy7
NBP1-43350PECY7
PerCP
NBP1-43350PCP
Unconjugated
NBP1-43350-0.1mg
mFluor Violet 450 SE
NBP1-43350MFV450
mFluor Violet 500 SE
NBP1-43350MFV500
mFluor Violet 610 SE
NBP1-43350MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP1-43350-0.1mg
BSA Free
NBP1-43350-0.1mg
BSA Free
NBP1-43350-0.05mg
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PDGFR alpha Antibody (APA5) [PE/Cy5.5] Summary

Immunogen
The immunogen for this antibody was CD140a.
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Rat
Gene
PDGFRA
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

In flow cytometry, we recommend using a cell surface staining protocol and fixation and permeabilization is not required to get staining. If fixation/permeabilization is needed for other markers in the same experiment, we recommend doing all surface staining prior to the fix/perm procedure. This antibody may not bind to a fixed epitope.

Reactivity Notes

Human reactivity reported from a verified customer review.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Alternate Names for PDGFR alpha Antibody (APA5) [PE/Cy5.5]

  • alpha-type platelet-derived growth factor receptor
  • CD140 antigen-like family member A
  • CD140a antigen
  • CD140a
  • EC 2.7.10
  • EC 2.7.10.1
  • MGC74795
  • PDGF R alpha
  • PDGFR alpha
  • PDGFR2
  • PDGFRA
  • PDGFRA/BCR fusion
  • PDGF-R-alpha
  • platelet-derived growth factor receptor, alpha polypeptide
  • rearranged-in-hypereosinophilia-platelet derived growth factor receptor alphafusion protein
  • RHEPDGFRA

Background

Platelet-derived growth factor receptors exhibit tyrosine-protein kinase activity and have been implicated in the control of cell proliferation, survival and migration. PDGF receptors, PDGFR-alpha and PDGFR-beta, have 5 extracellular immunoglobulin-like domains and an intracellular tyrosine kinase domain. Upon binding a PDGF, the receptors form homo-and heterodimers. Dimerization of the receptors results in phosphorylation in the complex. More than 10 different SH2-domain-containing molecules have been shown to bind to different autophosphorylation sites in the PDGF-alpha and beta receptors. PDGF alpha receptors are expressed in oligodendrocyte progenitor cells and PDGF beta receptors are expressed on neurons.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol PDGFRA