PDGF R beta Antibody Pair [HRP]

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Sandwich ELISA: PDGF R beta Antibody Pair [HRP] [NBP2-79481] - This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP
Standard Curve Range
62.5-4000 pg/ml (example only; lot dependent)
Sensitivity
62.5 pg/ml (example only; lot dependent)

Order Details

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Catalog# & Conjugate Size Price

PDGF R beta Antibody Pair [HRP] Summary

Description
Solid Phase sandwich ELISA for the quantitative determination of Human PDGF R beta.
Specificity
This solid phase sandwich ELISA utilizes a monoclonal antibody specific for Human PDGF R beta.
Standard Curve Range
62.5-4000 pg/ml (example only; lot dependent)
Sensitivity
62.5 pg/ml (example only; lot dependent)
Assay Type
Sandwich ELISA
Sample Volume
100 ul
Gene
PDGFRB

Applications/Dilutions

Dilutions
  • ELISA
  • Sandwich ELISA

Packaging, Storage & Formulations

Storage
Storage of components varies. See protocol for specific instructions.

Kit Components

Components
  1. Mouse Monoclonal Capture Antibody
  2. Mouse Monoclonal Detection Antibody (HRP-conjugated)
  3. Standard

Alternate Names for PDGF R beta Antibody Pair [HRP]

  • beta-type platelet-derived growth factor receptor
  • CD140 antigen-like family member B
  • CD140b antigen
  • CD140b
  • EC 2.7.10
  • EC 2.7.10.1
  • JTK12
  • PDGF R beta
  • PDGFR
  • PDGFR1
  • PDGFRB
  • PDGF-R-beta
  • platelet-derived growth factor receptor, beta polypeptide

Background

Human platelet-derived growth factor (PDGF) receptor, is a receptor tyrosine kinase whose activity induces various signalling cascades leading to cell growth and proliferation. Two major isoforms exist, PDGF receptor-alpha and PDGF receptor-beta. PDGF receptor-beta can only bind two specific PDGF isoforms, PDGF-beta and PDGF-delta (1,2). Upon ligand binding, the receptor undergoes autophosphorylation, allowing binding and activation of cytoplasmic SH2 domain-containing signal transduction molecules such as PI kinase (3), Grb2, and Src, among others.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

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Product General Protocols

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Bioinformatics

Gene Symbol PDGFRB