PDGF R beta Antibody Pair [HRP] Summary
Description |
Solid Phase sandwich ELISA for the quantitative determination of Human PDGF R beta. |
Specificity |
This solid phase sandwich ELISA utilizes a monoclonal antibody specific for Human PDGF R beta. |
Standard Curve Range |
62.5-4000 pg/ml (example only; lot dependent) |
Sensitivity |
62.5 pg/ml (example only; lot dependent) |
Assay Type |
Sandwich ELISA |
Sample Volume |
100 ul |
Gene |
PDGFRB |
Applications/Dilutions
Packaging, Storage & Formulations
Storage |
Storage of components varies. See protocol for specific instructions. |
Kit Components
Components
|
- Mouse Monoclonal Capture Antibody
- Mouse Monoclonal Detection Antibody (HRP-conjugated)
- Standard
|
Alternate Names for PDGF R beta Antibody Pair [HRP]
Background
Human platelet-derived growth factor (PDGF) receptor, is a receptor tyrosine kinase whose activity induces various signalling cascades leading to cell growth and proliferation. Two major isoforms exist, PDGF receptor-alpha and PDGF receptor-beta. PDGF receptor-beta can only bind two specific PDGF isoforms, PDGF-beta and PDGF-delta (1,2). Upon ligand binding, the receptor undergoes autophosphorylation, allowing binding and activation of cytoplasmic SH2 domain-containing signal transduction molecules such as PI kinase (3), Grb2, and Src, among others.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are
guaranteed for 6 months from date of receipt.
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