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PDGF R beta Antibody (APB5) [Janelia Fluor® 549]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow, IHC, MA
Clone
APB5
Clonality
Monoclonal
Host
Rat
Conjugate
Janelia Fluor 549

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP1-43349AF350
Alexa Fluor 405
NBP1-43349AF405
Alexa Fluor 488
NBP1-43349AF488
Alexa Fluor 532
NBP1-43349AF532
Alexa Fluor 594
NBP1-43349AF594
Alexa Fluor 647
NBP1-43349AF647
Alexa Fluor 700
NBP1-43349AF700
Alexa Fluor 750
NBP1-43349AF750
Allophycocyanin
NBP1-43349APC
Biotin
NBP1-43580-0.1mg
Biotin
NBP1-43580-0.025mg
CoraFluor 1
NBP1-43349CL1
DyLight 350
NBP1-43349UV
DyLight 405
NBP1-43349V
DyLight 488
NBP1-43349G
DyLight 550
NBP1-43349R
DyLight 594
NBP1-43349DL594
DyLight 650
NBP1-43349C
DyLight 680
NBP1-43349FR
DyLight 755
NBP1-43349IR
FITC
NBP1-43349F
HRP
NBP1-43349H
Janelia Fluor 525
NBP1-43349JF525
Janelia Fluor 585
NBP1-43349JF585
Janelia Fluor 635
NBP1-43349JF635
Janelia Fluor 646
NBP1-43349JF646
Janelia Fluor 669
NBP1-43349JF669
PE
NBP1-43349PE
PerCP
NBP1-43349PCP
Unconjugated
NBP1-43349-0.1mg
mFluor Violet 450 SE
NBP1-43349MFV450
mFluor Violet 500 SE
NBP1-43349MFV500
mFluor Violet 610 SE
NBP1-43349MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP1-43349-0.1mg
BSA Free
NBP1-43349-0.1mg
BSA Free
NBP1-43349-0.05mg
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PDGF R beta Antibody (APB5) [Janelia Fluor® 549] Summary

Immunogen
The immunogen for this antibody was PDGF receptor beta.
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Rat
Gene
PDGFRB
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Protein Array
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for PDGF R beta Antibody (APB5) [Janelia Fluor® 549]

  • beta-type platelet-derived growth factor receptor
  • CD140 antigen-like family member B
  • CD140b antigen
  • CD140b
  • EC 2.7.10
  • EC 2.7.10.1
  • JTK12
  • PDGF R beta
  • PDGFR
  • PDGFR1
  • PDGFRB
  • PDGF-R-beta
  • platelet-derived growth factor receptor, beta polypeptide

Background

Human platelet-derived growth factor (PDGF) receptor, is a receptor tyrosine kinase whose activity induces various signalling cascades leading to cell growth and proliferation. Two major isoforms exist, PDGF receptor-alpha and PDGF receptor-beta. PDGF receptor-beta can only bind two specific PDGF isoforms, PDGF-beta and PDGF-delta (1,2). Upon ligand binding, the receptor undergoes autophosphorylation, allowing binding and activation of cytoplasmic SH2 domain-containing signal transduction molecules such as PI kinase (3), Grb2, and Src, among others.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol PDGFRB