PDGF R beta Antibody (APB5) [Allophycocyanin] Summary
Immunogen |
The immunogen for this antibody was PDGF receptor beta. |
Isotype |
IgG2a Kappa |
Clonality |
Monoclonal |
Host |
Rat |
Gene |
PDGFRB |
Purity |
Protein A or G purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Flow Cytometry
- Immunohistochemistry
- Immunohistochemistry-Frozen
- Protein Array
|
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
PBS |
Preservative |
0.05% Sodium Azide |
Purity |
Protein A or G purified |
Alternate Names for PDGF R beta Antibody (APB5) [Allophycocyanin]
Background
Human platelet-derived growth factor (PDGF) receptor, is a receptor tyrosine kinase whose activity induces various signalling cascades leading to cell growth and proliferation. Two major isoforms exist, PDGF receptor-alpha and PDGF receptor-beta. PDGF receptor-beta can only bind two specific PDGF isoforms, PDGF-beta and PDGF-delta (1,2). Upon ligand binding, the receptor undergoes autophosphorylation, allowing binding and activation of cytoplasmic SH2 domain-containing signal transduction molecules such as PI kinase (3), Grb2, and Src, among others.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Publications for PDGF R beta Antibody (NBP1-43349APC) (0)
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Product General Protocols
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FAQs for PDGF R beta Antibody (NBP1-43349APC). (Showing 1 - 1 of 1 FAQ).
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The data sheet says that your antibody NBP1-43349APC, anti PDGF receptor beta antibody can be used for FACS. This antibody can be used for living cells? or I need to fix the cells before I label cells with this antibody? I need to isolate cells using NBP1
- For our product NBP1-43349APC, we have not tested this product directly with a live cell population, but we have tested it with our standard extracellular staining protocol (which does not include a fixation step): Protocol. It is possible that this product will work with your live cell population, and if you would like to report your results to us as a review, we can offer you our Innovator's Reward credit. This credit will be worth the purchase price of the antibody and can be used in any future purchase of your choice. Details can be found here: Innovators Reward
Secondary Antibodies
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Isotype Controls
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