PCMT1 Antibody

Three classes of protein carboxyl methyltransferases, distinguished by their methyl-acceptor substrate specificity, have been found in prokaryotic and eukaryotic cells. The type II enzyme catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to the free carboxyl groups of D-aspartyl and L-isoaspartyl residues. These methyl-accepting residues result from the spontaneous deamidation, isomerization, and racemization of normal L-aspartyl and L-asparaginyl residues and represent sites of covalent damage to aging proteins PCMT1 (EC 2.1.1.77) is a protein repair enzyme that initiates the conversion of abnormal D-aspartyl and L-isoaspartyl residues to the normal L-aspartyl form.[supplied by OMIM]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publication using NBP1-85806	Applications	Species
Forsstrom B, Axnas BB, Stengele KP et al. Proteome-wide Epitope Mapping of Antibodies Using Ultra-dense Peptide Arrays. Mol Cell Proteomics 2014-06-01 [PMID: 24705123]

Array NBP1-85806

• PCMT1 Antibodies
• PCMT1 ELISA Kits
• PCMT1 Lysate
• PCMT1 Proteins