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p67phox/NOXA2 Antibody (7J7N3)

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Western Blot: p67phox/NOXA2 Antibody (7J7N3) [NBP3-16257] - Western blot analysis of extracts of various cell lines, using p67phox/NOXA2 Rabbit mAb (NBP3-16257) at 1:1000 dilution. Secondary antibody: HRP Goat ...read more
Immunohistochemistry-Paraffin: p67phox/NOXA2 Antibody (7J7N3) [NBP3-16257] - Immunohistochemistry of paraffin-embedded mouse kidney using p67phox/NOXA2 Rabbit mAb (NBP3-16257) at dilution of 1:100 (40x lens).Perform ...read more

Product Details

Summary
Reactivity Mu, RtSpecies Glossary
Applications WB, ELISA, IHC
Clone
7J7N3
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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p67phox/NOXA2 Antibody (7J7N3) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 200-300 of human p67phox/NOXA2 (P19878). GKATVVASVVDQDSFSGFAPLQPQAAEPPPRPKTPEIFRALEGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELR
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
NCF2
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin
  • Western Blot 1:500 - 1:1000
Theoretical MW
60 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 50% glycerol, 0.05% BSA
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for p67phox/NOXA2 Antibody (7J7N3)

  • autosomal 2
  • NADPH oxidase activator 2
  • NCF2
  • NCF-2
  • neutrophil cytosol factor 2
  • neutrophil cytosolic factor 2 (65kD, chronic granulomatous disease, autosomal2)
  • neutrophil cytosolic factor 2
  • NOXA2
  • NOXA2FLJ93058
  • p67phox
  • p67-phox

Background

NOXA2 encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in two transcript variants that encode the same protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol NCF2