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Ornithine Carbamoyltransferase Antibody (OTI8A1) [Janelia Fluor® 669]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC
Clone
OTI8A1
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 669

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-73149AF350
Alexa Fluor 405
NBP2-73149AF405
Alexa Fluor 488
NBP2-73149AF488
Alexa Fluor 532
NBP2-73149AF532
Alexa Fluor 594
NBP2-73149AF594
Alexa Fluor 647
NBP2-73149AF647
Alexa Fluor 700
NBP2-73149AF700
Alexa Fluor 750
NBP2-73149AF750
Allophycocyanin
NBP2-73149APC
Biotin
NBP2-73149B
CoraFluor 1
NBP2-73149CL1
DyLight 350
NBP2-73149UV
DyLight 405
NBP2-73149V
DyLight 488
NBP2-73149G
DyLight 550
NBP2-73149R
DyLight 594
NBP2-73149DL594
DyLight 650
NBP2-73149C
DyLight 680
NBP2-73149FR
DyLight 755
NBP2-73149IR
FITC
NBP2-73149F
HRP
NBP2-73149H
Janelia Fluor 525
NBP2-73149JF525
Janelia Fluor 585
NBP2-73149JF585
Janelia Fluor 635
NBP2-73149JF635
PE
NBP2-73149PE
PerCP
NBP2-73149PCP
Unconjugated
NBP2-46303
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-46303
Azide and BSA Free
NBP2-73149
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Ornithine Carbamoyltransferase Antibody (OTI8A1) [Janelia Fluor® 669] Summary

Immunogen
Human recombinant protein fragment corresponding to amino acids 33-354 of human OTC (NP_000522)produced in E.coli.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
OTC
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Ornithine Carbamoyltransferase Antibody (OTI8A1) [Janelia Fluor® 669]

  • EC 2.1.3
  • EC 2.1.3.3
  • MGC129967
  • MGC129968
  • MGC138856
  • OCTD
  • Ornithine Carbamoyltransferase
  • ornithine carbamoyltransferase, mitochondrial
  • Ornithine Transcarbamylase
  • OTC
  • OTCase

Background

This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol OTC