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Ornithine Carbamoyltransferase Antibody (OTI8A1) [Biotin]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications IHC
Clone
OTI8A1
Clonality
Monoclonal
Host
Mouse
Conjugate
Biotin

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Ornithine Carbamoyltransferase Antibody (OTI8A1) [Biotin] Summary

Immunogen
Recombinant protein fragment corresponding to amino acids 33-354 of human Ornithine Carbamoyltransferase (NP_000522)produced in E.coli.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
OTC
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Ornithine Carbamoyltransferase Antibody (OTI8A1) [Biotin]

  • EC 2.1.3
  • EC 2.1.3.3
  • MGC129967
  • MGC129968
  • MGC138856
  • OCTD
  • Ornithine Carbamoyltransferase
  • ornithine carbamoyltransferase, mitochondrial
  • Ornithine Transcarbamylase
  • OTC
  • OTCase

Background

This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol OTC