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Olig1 Antibody (7E4B2)

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Western Blot: Olig1 Antibody (7E4B2) [NBP3-15326] - Western blot analysis of extracts of various cell lines, using Olig1 Rabbit mAb (NBP3-15326) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at ...read more

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB
Clone
7E4B2
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Olig1 Antibody (7E4B2) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 172-271 of human Olig1 (Q8TAK6). RRALGEGAGPAAPRLLLAGLPLLAAAPGSVLLAPGAVGPPDALRPAKYLSLALDEPPCGQFALPGGGAGGPGLCTCAVCKFPHLVPASLGLAAVQAQFSK
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
OLIG1
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500 - 1:1000

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS, 0.05% BSA, 50% glycerol, pH7.3
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for Olig1 Antibody (7E4B2)

  • BHLHB6
  • bHLHe21
  • Class B basic helix-loop-helix protein 6
  • Class E basic helix-loop-helix protein 21
  • helix-loop-helix protein, class B, 6
  • Olig1
  • oligo1
  • oligodendrocyte lineage transcription factor 1
  • oligodendrocyte transcription factor 1
  • oligodendrocyte-specific bHLH transcription factor 1

Background

Olig genes have been identified as the earliest known markers of oligodendrocyte lineage determination to date (Zhou et al., 2000). Olig1 is a transcription factor which promotes formation and maturation of oligodendrocytes, especially within the brain. It is expressed in the ventral spinal cord as early as 9.5 dpc and by 15.5 dpc, olig1 is dispersed throughout the gray matter. In the postnatal brain, it is present preferentially in the white matter, such as corpus callosum and cerebellar medulla. Olig1 has been demonstrated as necessary in the repair of brain lesions in patients with multiple sclerosis (Arnett et al. 2004).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Array NBP3-15326

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Bioinformatics

Gene Symbol OLIG1