Nestin Antibody

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Nestin is a 240 kDa class VI intermediate filament protein that was first identified in neuroepithelial stem cells (1, 2). It has been used extensively as a marker to identify central nervous system (CNS) stem cell populations. In addition, Nestin has been found to be a marker for multi-lineage progenitor cells. Over the region used for immunization, rat Nestin shares 76% amino acid sequence homology with the mouse protein.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 3 confirmed species: Human, Mouse, Rat.

We have publications tested in 6 applications: ICC, IF, IHC, IHC-Fr, IHC-P, Western Blot.

Showing Publications 1 - 10 of 17. Show All 17 Publications. Collapse Publications.

Publications using AF2736	Applications	Species
Jim�nez-Madrona E, Morado-D�az CJ, Talaver�n R et al. Antiproliferative effect of boldine on neural progenitor cells and on glioblastoma cells Frontiers in Neuroscience 2023-08-16 [PMID: 37655012]
BC Fong, I Chakroun, MA Iqbal, S Paul, J Bastasic, D O'Neil, E Yakubovich, AT Bejjani, N Ahmadi, A Carter, A Clark, G Leone, DS Park, N Ghanem, R Vandenbosc, RS Slack The Rb/E2F axis is a key regulator of the molecular signatures instructing the quiescent and activated adult neural stem cell state Cell Reports, 2022-11-01;41(5):111578. 2022-11-01 [PMID: 36323247] (ICC, Mouse)	ICC	Mouse
Sofiane Miloudi, Maud Valensi, Mohamed El Sanharawi, Marc M. Abitbol, Francine Behar-Cohen, Claudine Versaux-Botteri Nestin contributes to laser choroidal and retinal neovascularization Mol Vis 2022-09-04 [PMID: 36284669]
O'Shea TM, Ao Y, Wang S et al. Lesion environments direct transplanted neural progenitors towards a wound repair astroglial phenotype in mice Nature Communications 2022-09-28 [PMID: 36171203]
Marissa A. Lithopoulos, Xavier Toussay, Shumei Zhong, Liqun Xu, Shamimunisa B. Mustafa, Julie Ouellette et al. Neonatal hyperoxia in mice triggers long-term cognitive deficits via impairments in cerebrovascular function and neurogenesis Journal of Clinical Investigation 2022-11-15 [PMID: 36136598]
L Chen, M Zhang, L Fang, X Yang, N Cao, L Xu, L Shi, Y Cao Coordinated regulation of the ribosome and proteasome by PRMT1 in the maintenance of neural stemness in cancer cells and neural stem cells The Journal of Biological Chemistry, 2021-10-04;297(5):101275. 2021-10-04 [PMID: 34619150] (IF, Mouse)	IF	Mouse
Alfonso Lavado, Ruchika Gangwar, Joshua Paré, Shibiao Wan, Yiping Fan, Xinwei Cao YAP/TAZ maintain the proliferative capacity and structural organization of radial glial cells during brain development Developmental Biology 2021-12-01 [PMID: 34419458]
Ayumu Sugiura, Tatsuhiro Shimizu, Takeshi Kameyama, Tomohiko Maruo, Shin Kedashiro, Muneaki Miyata et al. Identification of Sox2 and NeuN Double-Positive Cells in the Mouse Hypothalamic Arcuate Nucleus and Their Reduction in Number With Aging Frontiers in Aging Neuroscience 2021-03-11 [PMID: 33776740]
K Xi, Y Gu, J Tang, H Chen, Y Xu, L Wu, F Cai, L Deng, H Yang, Q Shi, W Cui, L Chen Microenvironment-responsive immunoregulatory electrospun fibers for promoting nerve function recovery Nat Commun, 2020-09-09;11(1):4504. 2020-09-09 [PMID: 32908131] (IHC, Rat)	IHC	Rat
S Cheng, T Liu, Y Hu, Y Xia, J Hou, C Huang, X Zou, J Liang, Y Stone Shi, Y Zheng, J Lu, G Chen Conditional inactivation of Pen-2 in the developing neocortex leads to rapid switch of apical progenitors to basal progenitors J. Neurosci., 2019-01-28;0(0):. 2019-01-28 [PMID: 30692224] (IHC-P, Mouse)	IHC-P	Mouse
Y Takamori, Y Hirahara, T Wakabayash, T Mori, T Koike, Y Kataoka, Y Tamura, S Kurebayash, K Kurokawa, H Yamada Differential expression of nuclear lamin subtypes in the neural cells of the adult rat cerebral cortex IBRO Rep, 2018-11-05;5(0):99-109. 2018-11-05 [PMID: 30505974] (IHC-Fr, Rat)	IHC-Fr	Rat
Wollenberg AL, O'Shea TM, Kim JH et al. Injectable polypeptide hydrogels via methionine modification for neural stem cell delivery Biomaterials 2018-09-01 [PMID: 29657091]
Takamori Y, Mori T, Wakabayashi T, Nagasaka Y, Matsuzaki T, Yamada H Nestin-positive microglia in adult rat cerebral cortex. Brain Res., 2009-03-21;1270(0):10-8. 2009-03-21 [PMID: 19306852] (IHC-Fr, Rat)	IHC-Fr	Rat
Gregorian C, Nakashima J, Le Belle J, Ohab J, Kim R, Liu A, Smith KB, Groszer M, Garcia AD, Sofroniew MV, Carmichael ST, Kornblum HI, Liu X, Wu H Pten deletion in adult neural stem/progenitor cells enhances constitutive neurogenesis. J. Neurosci., 2009-02-11;29(6):1874-86. 2009-02-11 [PMID: 19211894] (IHC-P, Mouse)	IHC-P	Mouse
Zoukhri D, Fix A, Alroy J, Kublin CL Mechanisms of murine lacrimal gland repair after experimentally induced inflammation. Invest. Ophthalmol. Vis. Sci., 2008-06-27;49(10):4399-406. 2008-06-27 [PMID: 18586880] (IHC-P, Western Blot, Mouse)	IHC-P, Western Blot	Mouse
Subburaju S, Aguilera G Vasopressin mediates mitogenic responses to adrenalectomy in the rat anterior pituitary. Endocrinology, 2007-04-05;148(7):3102-10. 2007-04-05 [PMID: 17412807] (IHC-Fr, Rat)	IHC-Fr	Rat
De Bank PA, Hou Q, Warner RM, Wood IV, Ali BE, Macneil S, Kendall DA, Kellam B, Shakesheff KM, Buttery LD Accelerated formation of multicellular 3-D structures by cell-to-cell cross-linking. Biotechnol. Bioeng., 2007-08-15;97(6):1617-25. 2007-08-15 [PMID: 17304565] (Western Blot, Human)	Western Blot	Human
Show All 17 Publications. Collapse Publications.

Images	Ratings	Applications	Species	Date	Details
	4 reviewed by: Verified Customer	IF	Rat	01/07/2015	View Summary Application Immunofluorescence Sample Tested See PMID 23399867 Species Rat
	4 reviewed by: Verified Customer	IF	Human	01/07/2015	View Summary Application Immunofluorescence Sample Tested See PMID 23996239 Species Human
	5 reviewed by: Verified Customer	IF	Rat	12/18/2014	View Summary Application Immunofluorescence Sample Tested transfected RN22 cells Species Rat
	5 reviewed by: Verified Customer	WB	Rat	12/18/2014	View Summary Application Western Blot Sample Tested RN22 cells Species Rat

Array AF2736

• Nestin Antibodies
• Nestin ELISA Kits
• Nestin Proteins