NTera-2 human testicular embryonic carcinoma cell line either untreated (dark orange filled histogram) or treated with 5 µM Retinoic Acid for 6 days (light orange filled histogram) was stained with Mouse Anti-Human ...read more
12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Nestin Antibody (196908) [Phycoerythrin]
FLJ21841
NES
Nestin
Background
Nestin is a class VI intermediate filament protein (1, 2) that is expressed in stem cells of the central nervous system (CNS) (3) but not in mature CNS cells (4). Nestin expression is used extensively as a marker for CNS stem cells in the developing nervous system and in vitro cultured cells (5-10). Its transient expression is a critical step in the neural differentiation pathway (2). Nestin is also expressed in non-neural stem cell populations, such as pancreatic islet progenitors (11-13) and hematopoietic progenitors (14).
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Tohyama, T. et. al. (1992) Lab. Invest. 66:303.
Uchida, N. et al. (2000) Proc. Natl. Acad.Sci. USA 97:14720.
Frederiksen, K. et al. (1988) Neuron 1:439.
Cattaneo, E. et al. (1990) Nature 347:762.
Reynolds, B.A. and S. Weiss (1992) Science 255:1707.
Rietze, R.L. et al. (2001) Nature 412:736.
Carpenter, M.K. et al. (2001) Exp. Neurol 172:383.
Zulewski, H. et al. (2001) Diabetes 50:521.
Lumelsky, N. et al. (2001) Science 292:1389.
Lechner, A. et al. (2002) Biochem.Biophys. Res. Commun. 293:670.
Shih, C.C. et al. (2001) Blood 98:2412.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Nestin Antibody Products in Neuronal Cancer Research Nestin is a large class Vl intermediate filament protein predominantly expressed in the neuroepithelial stem cells of the embryonic central nervous system, although recent nestin antibody studies have shown it expressed in other cell types, including ... Read full blog post.
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