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MSX2 Antibody

Images

 
Immunohistochemistry-Paraffin: MSX2 Antibody [NBP1-85445] - Staining of human placenta shows strong nuclear positivity in trophoblastic cells.
Immunohistochemistry-Paraffin: MSX2 Antibody [NBP1-85445] - Staining of human urinary bladder shows weak nuclear positivity in urothelial cells.
Immunohistochemistry-Paraffin: MSX2 Antibody [NBP1-85445] - Staining of human endometrium shows moderate nuclear positivity in glandular cells.
Immunohistochemistry-Paraffin: MSX2 Antibody [NBP1-85445] - Staining of human liver shows low positivity in hepatocytes as expected.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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MSX2 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: SSLPFSVEALMSDKKPPKEASPLPAESASAGATLRPLLLSGHGAREAHSPGPLVKPFETASVKSENSEDGAAWMQEPGRYSPPPRHTSPTTCTLRKHKTNRKP
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MSX2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50-1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
MSX2 Protein (NBP1-85445PEP)
Publications
Read Publications using NBP1-85445.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for MSX2 Antibody

  • CRS2
  • CRS2parietal foramina 1
  • FPP
  • Homeobox protein Hox-8
  • homeobox protein MSX-2
  • Hox8
  • HOX8msh homeobox homolog 2 (Drosophila)
  • msh (Drosophila) homeo box homolog 2
  • msh homeo box 2
  • msh homeobox 2
  • msh homeobox homolog 2
  • MSH
  • MSX2
  • PFM
  • PFM1

Background

Msx2/Hox8 encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for MSX2 Antibody (NBP1-85445)(4)

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

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Blogs on MSX2

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Bioinformatics

Gene Symbol MSX2