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GGPS1 Antibody

Images

 
Western Blot: GGPS1 Antibody [NBP1-83368] - Analysis in control (vector only transfected HEK293T lysate) and GGPS1 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Immunohistochemistry-Paraffin: GGPS1 Antibody [NBP1-83368] - Staining of human liver shows no positivity in hepatocytes as expected.
Western Blot: GGPS1 Antibody [NBP1-83368] - Analysis in human cell line RT-4.
Immunohistochemistry-Paraffin: GGPS1 Antibody [NBP1-83368] - Staining of human pancreas shows low expression as expected.
Immunohistochemistry-Paraffin: GGPS1 Antibody [NBP1-83368] - Staining of human testis shows high expression.
Orthogonal Strategies: Immunohistochemistry-Paraffin: GGPS1 Antibody [NBP1-83368] - Staining in human testis and pancreas tissues using anti-GGPS1 antibody. Corresponding GGPS1 RNA-seq data are presented for the ...read more
Orthogonal Strategies: Immunohistochemistry-Paraffin: GGPS1 Antibody [NBP1-83368] - Analysis in human testis and skeletal muscle tissues. Corresponding GGPS1 RNA-seq data are presented for the same tissues.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

Order Details

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GGPS1 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: CEDLTEGKFSFPTIHAIWSRPESTQVQNILRQRTENIDIKKYCVHYLEDVGSFEYTRNTLKELEAKAYKQIDARGGNPELVALVKHLSKMFKE
Predicted Species
Mouse (91%), Rat (92%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GGPS1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
  • Western Blot 0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
GGPS1 Protein (NBP1-83368PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for GGPS1 Antibody

  • 6E)-farnesyl diphosphate synthase
  • dimethylallyltranstransferase
  • EC 2.5.1.1
  • EC 2.5.1.10
  • EC 2.5.1.29
  • Farnesyl diphosphate synthase
  • Farnesyltranstransferase
  • geranylgeranyl diphosphate synthase 1
  • Geranylgeranyl diphosphate synthase
  • geranylgeranyl pyrophosphate synthase
  • geranyltranstransferase
  • GGPP synthase
  • GGPPS
  • GGPPS1farnesyltranstransferase
  • GGPPSase

Background

GGPS1 is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol GGPS1