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Melanoma Marker (MART-1 + Tyrosinase + gp100) Antibody (M2-7C10 + M2-9E3 + T311 + HMB45) [Janelia Fluor® 646]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF, IHC
Clone
M2-7C10 + M2-9E3 + T311 + HMB45
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 646

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-34681AF350
Alexa Fluor 405
NBP2-34681AF405
Alexa Fluor 488
NBP2-34681AF488
Alexa Fluor 532
NBP2-34681AF532
Alexa Fluor 594
NBP2-34681AF594
Alexa Fluor 647
NBP2-34681AF647
Alexa Fluor 700
NBP2-34681AF700
Alexa Fluor 750
NBP2-34681AF750
Biotin
NBP2-34681B
CoraFluor 1
NBP2-34681CL1
DyLight 350
NBP2-34681UV
DyLight 405
NBP2-34681V
DyLight 488
NBP2-34681G
DyLight 550
NBP2-34681R
DyLight 594
NBP2-34681DL594
DyLight 650
NBP2-34681C
DyLight 680
NBP2-34681FR
DyLight 755
NBP2-34681IR
FITC
NBP2-34681F
HRP
NBP2-34681H
Janelia Fluor 525
NBP2-34681JF525
Janelia Fluor 549
NBP2-34681JF549
Janelia Fluor 585
NBP2-34681JF585
Janelia Fluor 635
NBP2-34681JF635
Janelia Fluor 669
NBP2-34681JF669
Unconjugated
NBP2-34681-0.1mg
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-34681-0.1mg
IHC-Prediluted
NBP2-48257
Azide and BSA Free
NBP2-34681-0.1mg
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Melanoma Marker (MART-1 + Tyrosinase + gp100) Antibody (M2-7C10 + M2-9E3 + T311 + HMB45) [Janelia Fluor® 646] Summary

Immunogen
Recombinant Melanoma Marker (MART-1 + Tyrosinase + gp100) protein (M2-7C10; M2-9E3); Recombinant tyrosinase protein (T311); Extract of pigmented melanoma metastases from lymph nodes (HMB45)
Localization
Cytoplasmic
Marker
Melanoma Marker
Specificity
This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
Isotype
IgG2b Lambda/IgG2a Kappa/IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
MLANA
Purity
Protein A or G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Array

  • MART1
  • MART-1
  • melan-A
  • MLANA

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Bioinformatics

Gene Symbol MLANA