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Melanoma Marker (MART-1 + Tyrosinase + gp100) Antibody (M2-7C10 + M2-9E3 + T311 + HMB45) [DyLight 488]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF, IHC
Clone
M2-7C10 + M2-9E3 + T311 + HMB45
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 488

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-34681AF350
Alexa Fluor 405
NBP2-34681AF405
Alexa Fluor 488
NBP2-34681AF488
Alexa Fluor 532
NBP2-34681AF532
Alexa Fluor 594
NBP2-34681AF594
Alexa Fluor 647
NBP2-34681AF647
Alexa Fluor 700
NBP2-34681AF700
Alexa Fluor 750
NBP2-34681AF750
Biotin
NBP2-34681B
CoraFluor 1
NBP2-34681CL1
DyLight 350
NBP2-34681UV
DyLight 405
NBP2-34681V
DyLight 550
NBP2-34681R
DyLight 594
NBP2-34681DL594
DyLight 650
NBP2-34681C
DyLight 680
NBP2-34681FR
DyLight 755
NBP2-34681IR
FITC
NBP2-34681F
HRP
NBP2-34681H
Janelia Fluor 525
NBP2-34681JF525
Janelia Fluor 549
NBP2-34681JF549
Janelia Fluor 585
NBP2-34681JF585
Janelia Fluor 635
NBP2-34681JF635
Janelia Fluor 646
NBP2-34681JF646
Janelia Fluor 669
NBP2-34681JF669
Unconjugated
NBP2-34681-0.1mg
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-34681-0.1mg
IHC-Prediluted
NBP2-48257
Azide and BSA Free
NBP2-34681-0.1mg
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Melanoma Marker (MART-1 + Tyrosinase + gp100) Antibody (M2-7C10 + M2-9E3 + T311 + HMB45) [DyLight 488] Summary

Description
This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Immunogen
Recombinant Melanoma Marker (MART-1 + Tyrosinase + gp100) protein (M2-7C10; M2-9E3); Recombinant tyrosinase protein (T311); Extract of pigmented melanoma metastases from lymph nodes (HMB45)
Localization
Cytoplasmic
Marker
Melanoma Marker
Specificity
This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
Isotype
IgG2b Lambda/IgG2a Kappa/IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
MLANA
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Western Blot

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Array

  • MART1
  • MART-1
  • melan-A
  • MLANA

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol MLANA