Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody

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Immunocytochemistry/ Immunofluorescence: Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody [NBP2-57484] - Staining of human cell line A-431 shows localization to nucleoplasm.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: ARFSTASDMRFEDTFYGADIIQGERKRQRVLSSRFKNEYVADPVYRTFLKSSFQKKCQK
Predicted Species
Mouse (95%), Rat (95%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
KDM4C
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
Application Notes
ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Recombinant Protein Antigen (NBP2-57484PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for Lysine (K)-specific Demethylase 4C/KDM4C/JMJD2C Antibody

  • EC 1.14.11
  • EC 1.14.11.-
  • GASC-1 protein
  • GASC1
  • GASC1JmjC domain-containing histone demethylation protein 3C
  • Gene amplified in squamous cell carcinoma 1 protein
  • JHDM3C
  • JMJD2C
  • JMJD2CbA146B14.1
  • jumonji domain containing 2C
  • Jumonji domain-containing protein 2C
  • KDM4C
  • KIAA0780FLJ25949
  • Lysine (K)specific Demethylase 4C
  • Lysine (K)-specific Demethylase 4C
  • lysine-specific demethylase 4C

Background

JMJD2C is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol KDM4C