Home » Latent TGF-beta bp1 » Latent TGF-beta bp1 Antibodies » Latent TGF-beta bp1 Antibody (35409) [Unconjugated]
Novus Biologicals products are now on bio-techne.com

Latent TGF-beta bp1 Antibody (35409) [Unconjugated]

 (11 Publications)
 See All Related
Submit a Review

Images

 
There are currently no images for Latent TGF-beta bp1 Antibody (MAB388).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, AP
Clone
35409
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Allophycocyanin
IC388A
View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
IC388A
Carrier Free
MAB388-SP
Carrier Free
MAB388-500
Novus Biologicals is part of Bio-Techne

Shop this product on bio-techne.com

Novus Biologicals, part of Bio-Techne, offers 100% Guarantee

Latent TGF-beta bp1 Antibody (35409) [Unconjugated] Summary

Immunogen
Human platelet-derived large latent TGF-beta 1 complex
Specificity
Detects human LTBP-1 from the large latent TGF-beta 1 complex.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
LTBP1
Purity Statement
Protein A or G purified from ascites
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Immunoaffinity Purification
  • Western Blot 1 ug/mL
Publications
Read Publications using
MAB388 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Latent TGF-beta bp1 Antibody (35409) [Unconjugated]

  • Latent TGFbeta bp1
  • Latent TGF-beta bp1
  • latent transforming growth factor beta binding protein 1
  • latent-transforming growth factor beta-binding protein 1
  • LTBP1
  • LTBP-1
  • MGC163161
  • TGF-beta1-BP-1
  • Transforming growth factor beta-1-binding protein 1

Background

TGF-beta  is synthesized as high molecular weight latent complexes. In platelets, the large latent TGF-beta 1 complex is composed of three components: mature TGF-beta 1 dimer; latency associated peptide; and a latent TGF-beta binding protein (LTBP) (1-3).The cDNAs for four binding proteins (LTBP-1, -2, -3 and -4) have now been cloned (4-5).
  1. Miyazono, K. et al. (1991) EMBO J. 10:1091.
  2. Moren, A. et al. (1994) J. Biol. Chem. 269:32469.
  3. Yin, W. et al. (1995) J. Biol. Chem. 270:10147.
  4. Kanzaki, T. et al. (1990) Cell 61:1051.
  5. Saharinen, J. et al. (1998) J. Biol. Chem. 273:18459.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

TGF-beta 1
[Unconjugated]
7754-BH/CF
Bioactivity TGF-beta 1 [Unconjugated]
(53 Publications)
Species: Hu
Applications: BA
Latent TGF-beta
bp2/LTBP-2 Antibody
AF3850
Western Blot Latent TGF-beta bp2/LTBP-2 Antibody
(1 Review)
(2 Publications)
Species: Hu
Applications: WB
LTBP3
Overexpression Lysate
NBP2-09509
Western Blot LTBP3 Overexpression Lysate
Species: Hu
Applications: WB
Latent TGF-beta
bp4 Antibody
AF2885
Latent TGF-beta bp4 Antibody
(7 Publications)
Species: Mu
Applications: WB
Fibrillin 1
Antibody
NBP1-84722
Immunohistochemistry-Paraffin Fibrillin 1 Antibody
Immunohistochemistry-Paraffin Fibrillin 1 Antibody
Immunohistochemistry-Paraffin Fibrillin 1 Antibody
(4 Publications)
Species: Hu
Applications: ICC/IF, IHC, IHC-P
ACP2 Antibody
(M1-4A12)
H00000053-M01
Western Blot ACP2 Antibody (M1-4A12)
ELISA ACP2 Antibody (M1-4A12)
Western Blot ACP2 Antibody (M1-4A12)
Species: Hu
Applications: ELISA, ICC/IF, IHC, IHC-P, KD, WB
CEBP Beta Antibody
(47A1) - BSA Free
NBP1-04266
Western Blot CEBP Beta Antibody (47A1) - BSA Free
Western Blot CEBP Beta Antibody (47A1) - BSA Free
(1 Review)
Species: Hu
Applications: ELISA, ICC/IF, WB
CENPJ Antibody
(1A5)
H00055835-M02
Immunoprecipitation CENPJ Antibody (1A5)
Western Blot CENPJ Antibody (1A5)
Sandwich ELISA CENPJ Antibody (1A5)
Species: Hu
Applications: ELISA, IP, S-ELISA, WB
PICALM Antibody
NBP1-86658
Western Blot PICALM Antibody
Immunohistochemistry-Paraffin PICALM Antibody
Immunohistochemistry-Paraffin PICALM Antibody
(7 Publications)
Species: Hu, Mu, Rt
Applications: IHC, IHC-P, WB
LAP3 Antibody
NBP1-82847
Immunohistochemistry-Paraffin LAP3 Antibody
Immunohistochemistry-Paraffin LAP3 Antibody
Immunohistochemistry-Paraffin LAP3 Antibody
Species: Hu
Applications: ICC/IF, IHC, IHC-P, WB
Fibronectin
Antibody - BSA Free
NBP1-91258
Western Blot Fibronectin Antibody - BSA Free
Western Blot Fibronectin Antibody - BSA Free
Western Blot Fibronectin Antibody - BSA Free
(11 Reviews)
(56 Publications)
Species: Bv, Ca, Eq, Fe, Hu, Mu, Po, Rt
Applications: ICC/IF, IHC, IHC-Fr, IHC-P, Simple Western, WB
TGF-beta 1
[Unconjugated]
7754-BH/CF
Bioactivity TGF-beta 1 [Unconjugated]
(53 Publications)
Species: Hu
Applications: BA
Plasminogen
Antibody
NB600-930
Western Blot Plasminogen Antibody
Western Blot Plasminogen Antibody
Western Blot Plasminogen Antibody
(2 Reviews)
(6 Publications)
Species: Hu, Rt
Applications: ELISA, WB
Smad2/3 Antibody
[Unconjugated]
AF3797
Western Blot Smad2/3 Antibody [Unconjugated]
Chromatin Immunoprecipitation (ChIP) Smad2/3 Antibody [Unconjugated]
Immunocytochemistry Smad2/3 Antibody [Unconjugated]
(1 Review)
(24 Publications)
Species: Hu, Mu
Applications: ChIP, ICC, IHC, Simple Western, WB
Elastin Antibody
(BA-4)
NB100-2076
Immunohistochemistry-Paraffin Elastin Antibody (BA-4)
Immunohistochemistry-Paraffin Elastin Antibody (BA-4)
Immunohistochemistry-Paraffin Elastin Antibody (BA-4)
(2 Reviews)
(11 Publications)
Species: Bv, Fe, Hu, Rb
Applications: ICC/IF, IHC, IHC-Fr, IHC-P, WB
EGF [Unconjugated]
236-EG
SDS-PAGE EGF [Unconjugated]
Bioactivity EGF [Unconjugated]
Cell Culture EGF [Unconjugated]
(845 Publications)
Species: Hu
Applications: BA
TGF-beta 2
[Unconjugated]
302-B2
SDS-PAGE TGF-beta 2 [Unconjugated]
Bioactivity TGF-beta 2 [Unconjugated]
(86 Publications)
Species: Hu
Applications: BA
AHR Antibody
NB100-128
Immunocytochemistry/ Immunofluorescence AHR Antibody
Gel Super Shift Assays AHR Antibody
Immunohistochemistry-Paraffin AHR Antibody
(1 Review)
(17 Publications)
Species: Hu, Mu, Rt
Applications: ChIP, GS, ICC/IF, IHC, IHC-P, WB
MMP-14/MT1-MMP
Antibody (128527) [Un ...
MAB9181
Flow Cytometry MMP-14/MT1-MMP Antibody (128527) [Unconjugated]
Immunohistochemistry MMP-14/MT1-MMP Antibody (128527) [Unconjugated]
(11 Publications)
Species: Hu
Applications: CyTOF-ready, Flow, IHC, IP, WB
Latent TGF-beta
bp1 Antibody (35409) ...
MAB388
Latent TGF-beta bp1 Antibody (35409) [Unconjugated]
Species: Hu
Applications: WB, AP

Publications for Latent TGF-beta bp1 Antibody (MAB388)(11)

We have publications tested in 2 confirmed species: Human, Primate - Macaca mulatta (Rhesus Macaque).

We have publications tested in 6 applications: ICC, IHC, IHC-Fr, IHC-P, Immunoprecipitation, Western Blot.


Filter By Application
ICC
(4)
IHC
(1)
IHC-Fr
(1)
IHC-P
(1)
Immunoprecipitation
(1)
Western Blot
(5)
All Applications
Filter By Species
Human
(8)
Primate - Macaca mulatta (Rhesus Macaque)
(1)
All Species
Showing Publications 1 - 10 of 11. Show All 11 Publications.
Publications using MAB388 Applications Species
AJ Alshawaf, S Viventi, W Qiu, G D'Abaco, B Nayagam, M Erlichster, G Chana, I Everall, J Ivanusic, E Skafidas, M Dottori Phenotypic and Functional Characterization of Peripheral Sensory Neurons derived from Human Embryonic Stem Cells Sci Rep, 2018-01-12;8(1):603. 2018-01-12 [PMID: 29330377] (ICC, Human) ICC Human
ATRA modulates mechanical activation of TGF-? by pancreatic stellate cells Sci Rep, 2016-07-04;6(0):27639. 2016-07-04 [PMID: 27375161] (IHC, Human) IHC Human
Franco Klingberg, Melissa L. Chow, Anne Koehler, Stellar Boo, Lara Buscemi, Thomas M. Quinn et al. Prestress in the extracellular matrix sensitizes latent TGF-beta 1 for activation Journal of Cell Biology 10/27/2014 [PMID: 25332161]
Jessica Kast, Patrizia Hanecker, Nathalie Beaufort, Armin Giese, Anne Joutel, Martin Dichgans et al. Sequestration of latent TGF-beta binding protein 1 into CADASIL-related Notch3-ECD deposits Acta Neuropathologica Communications 12/1/2014 [PMID: 25190493]
Brophy T, Coller B, Ahamed J Identification of the thiol isomerase-binding peptide, mastoparan, as a novel inhibitor of shear-induced transforming growth factor beta1 (TGF-beta1) activation. J Biol Chem, 2013-03-05;288(15):10628-39. 2013-03-05 [PMID: 23463512] (Western Blot, Human) Western Blot Human
Willet J, Pichitsiri W, Jenkinson S, Brain J, Wood K, Alhasan A, Spielhofer J, Robertson H, Ali S, Kirby J Kidney transplantation: analysis of the expression and T cell-mediated activation of latent TGF-beta. J Leukoc Biol, 2012-11-27;93(4):471-8. 2012-11-27 [PMID: 23192429] (ICC, IHC-P, Human) ICC, IHC-P Human
Shen M, Siu S, Byrd S, Edelmann KH, Patel N, Ketchem RR, Mehlin C, Arnett HA, Hasegawa H Diverse functions of reactive cysteines facilitate unique biosynthetic processes of aggregate-prone interleukin-31. Exp. Cell Res., 2010-12-21;317(7):976-93. 2010-12-21 [PMID: 21182835] (Western Blot, Human) Western Blot Human
Massam-Wu T, Chiu M, Choudhury R Assembly of fibrillin microfibrils governs extracellular deposition of latent TGF beta. J. Cell. Sci., 2010-08-10;123(0):3006-18. 2010-08-10 [PMID: 20699357] (ICC, Immunoprecipitation, Western Blot, Human) ICC, Immunoprecipitation, Western Blot Human
Vehvilainen P, Hyytiainen M, Keski-Oja J Matrix association of latent TGF-beta binding protein-2 (LTBP-2) is dependent on fibrillin-1. J. Cell. Physiol., 2009-12-01;221(3):586-93. 2009-12-01 [PMID: 19681046] (ICC, Western Blot, Human) ICC, Western Blot Human
Gomez D, Al Haj Zen A, Borges LF, Philippe M, Gutierrez PS, Jondeau G, Michel JB, Vranckx R Syndromic and non-syndromic aneurysms of the human ascending aorta share activation of the Smad2 pathway. J. Pathol., 2009-05-01;218(1):131-42. 2009-05-01 [PMID: 19224541] (IHC-Fr, Human) IHC-Fr Human
Show All 11 Publications.

Reviews for Latent TGF-beta bp1 Antibody (MAB388) (0)

There are no reviews for Latent TGF-beta bp1 Antibody (MAB388). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for Latent TGF-beta bp1 Antibody (MAB388) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional Latent TGF-beta bp1 Products

Blogs on Latent TGF-beta bp1

There are no specific blogs for Latent TGF-beta bp1, but you can read our latest blog posts.
Read our latest blog and use the new citation tool on bio-techne.com

Contact Information

Product PDFs

  PDF SDS
  PDF Datasheet
  Request CofA

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Latent TGF-beta bp1 Antibody (35409) [Unconjugated] and receive a gift card or discount.


Bioinformatics

Gene Symbol LTBP1