KMT3B/NSD1 Antibody

KMT3B/NSD1 is a histone methyltransferase that preferentially methylates Lys-36 of histone H3 and Lys-20 of histone H4. KMT3B/NSD1 can function as an androgen receptor coactivator and is capable of both negatively and positively influencing transcription. Mutations in KMT3B/NSD1 are responsible for Sotos syndrome, Weaver syndrome, Beckwith-Wiedemann syndrome, and a form of childhood leukemia. Alternate names for KMT3B/NSD1 include nuclear receptor binding SET domain protein 1, ARA267, ARA-267 androgen receptor-associated coregulator 267, STO, SOTOS, Sotos syndrome, and FLJ22263.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publication 1 - 1 of 1.

Publication using NB100-1744	Applications	Species
Quintana RM, Dupuy AJ, Bravo A et al. A transposon-based analysis of gene mutations related to skin cancer development. J Invest Dermatol 2013-01-01 [PMID: 22832494]

Array NB100-1744

• KMT3B/NSD1 Antibodies
• KMT3B/NSD1 Proteins